14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation

TET2 stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer

(2019) Hao Chen et al.   CELL RESEARCH

Ascorbic acid–induced TET activation mitigates adverse hydroxymethylcytosine loss in renal cell carcinoma

(2019) Niraj Shenoy et al.   JOURNAL OF CLINICAL INVESTIGATION

Restoration of 5‐hydroxymethylcytosine by ascorbate blocks kidney tumour growth

(2018) Guangzhe Ge et al.   EMBO REPORTS

Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer

(2018) Di Wu et al.   NATURE

Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress

(2017) Yang W. Zhang et al.   MOLECULAR CELL

TET-mediated active DNA demethylation: mechanism, function and beyond

(2017) Xiaoji Wu et al.   NATURE REVIEWS GENETICS

TET2 binds the androgen receptor and loss is associated with prostate cancer

(2016) M L Nickerson et al.   ONCOGENE

14-3-3-Pred: improved methods to predict 14-3-3-binding phosphopeptides

(2015) Fábio Madeira et al.   BIOINFORMATICS

Inhibition of AMP Kinase by the Protein Phosphatase 2A Heterotrimer, PP2APpp2r2d

(2015) Biny K. Joseph et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of TET Protein Stability by Calpains

(2014) Yu Wang et al.   Cell Reports

Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer

(2013) Parthasarathy Seshacharyulu et al.   CANCER LETTERS

Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation

(2013) Lulu Hu et al.   CELL

Activation of NF- B signalling by fusicoccin-induced dimerization

(2012) M. Skwarczynska et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

14-3-3 and its binding partners are regulators of protein–protein interactions during spermatogenesis

(2009) Shengyi Sun et al.   JOURNAL OF ENDOCRINOLOGY

Acquired mutations in TET2 are common in myelodysplastic syndromes

(2009) Saskia M C Langemeijer et al.   NATURE GENETICS

Mutation inTET2in Myeloid Cancers

(2009) François Delhommeau et al.   NEW ENGLAND JOURNAL OF MEDICINE