An engineered variant of SETD3 methyltransferase alters target specificity from histidine to lysine methylation

Post-translational modifications and chromatin dynamics

(2019) Thomas O. Tolsma et al.   Essays in Biochemistry

KMT9 monomethylates histone H4 lysine 12 and controls proliferation of prostate cancer cells

(2019) Eric Metzger et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structural insights into SETD3-mediated histidine methylation on β-actin

(2019) Qiong Guo et al.   eLife

Lysine methylation signaling of non-histone proteins in the nucleus

(2019) Dan Levy   CELLULAR AND MOLECULAR LIFE SCIENCES

Introduction to the multi-author review on methylation in cellular physiology

(2019) David Shechter   CELLULAR AND MOLECULAR LIFE SCIENCES

Enterovirus pathogenesis requires the host methyltransferase SETD3

(2019) Jonathan Diep et al.   Nature Microbiology

Human HemK2/KMT9/N6AMT1 is an active protein methyltransferase, but does not act on DNA in vitro, in the presence of Trm112

(2019) Clayton B. Woodcock et al.   Cell Discovery

Structural basis for the target specificity of actin histidine methyltransferase SETD3

(2019) Shaobo Dai et al.   Nature Communications

SETD3 is an actin histidine methyltransferase that prevents primary dystocia

(2018) Alex W. Wilkinson et al.   NATURE

SETD3 protein is the actin-specific histidine N-methyltransferase

(2018) Sebastian Kwiatkowski et al.   eLife

Substrate Specificity of the HEMK2 Protein Glutamine Methyltransferase and Identification of Novel Substrates

(2016) Denis Kusevic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methyltransferase-Glo: a universal, bioluminescent and homogenous assay for monitoring all classes of methyltransferases

(2016) Kevin Hsiao et al.   Epigenomics

Nonhistone Lysine Methylation in the Regulation of Cancer Pathways

(2016) Scott M. Carlson et al.   Cold Spring Harbor Perspectives in Medicine

Use of knowledge-based restraints inphenix.refineto improve macromolecular refinement at low resolution

(2012) Jeffrey J. Headd et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The SET8 H4K20 protein lysine methyltransferase has a long recognition sequence covering seven amino acid residues

(2012) Srikanth Kudithipudi et al.   BIOCHIMIE

Specificity Analysis-Based Identification of New Methylation Targets of the SET7/9 Protein Lysine Methyltransferase

(2011) Arunkumar Dhayalan et al.   CHEMISTRY & BIOLOGY

Structural basis of SETD6-mediated regulation of the NF-kB network via methyl-lysine signaling

(2011) Yanqi Chang et al.   NUCLEIC ACIDS RESEARCH

Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling

(2010) Dan Levy et al.   NATURE IMMUNOLOGY

Rubisco in complex with Rubisco large subunit methyltransferase

(2009) S. Raunser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Analysis of the Substrate Specificity of the Dim-5 Histone Lysine Methyltransferase Using Peptide Arrays

(2008) Philipp Rathert et al.   CHEMISTRY & BIOLOGY

HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1

(2008) Sabine Figaro et al.   FEBS LETTERS

Protein lysine methyltransferase G9a acts on non-histone targets

(2008) Philipp Rathert et al.   Nature Chemical Biology