The regulatory proteins DSCR6 and Ezh2 oppositely regulate Stat3 transcriptional activity in mesoderm patterning during Xenopus development

PRC2 functions in development and congenital disorders

(2019) Orla Deevy et al.   DEVELOPMENT

Collagen triple helix repeat containing 1a (Cthrc1a) regulates cell adhesion and migration during gastrulation in zebrafish

(2019) Xiao-Ning Cheng et al.   EXPERIMENTAL CELL RESEARCH

STAT3: a multifaceted oncoprotein

(2018) Aleks C. Guanizo et al.   GROWTH FACTORS

Leukemia inhibitory factor signaling in Xenopus embryo: Insights from gain of function analysis and dominant negative mutant of the receptor

(2018) Sandra Jalvy et al.   DEVELOPMENTAL BIOLOGY

Responses to Cytokines and Interferons that Depend upon JAKs and STATs

(2017) George R. Stark et al.   Cold Spring Harbor Perspectives in Biology

Leucine repeat adaptor protein 1 interacts with Dishevelled to regulate gastrulation cell movements in zebrafish

(2017) Xiao-Ning Cheng et al.   Nature Communications

PRC2 specifies ectoderm lineages and maintains pluripotency in primed but not naïve ESCs

(2017) Yongli Shan et al.   Nature Communications

Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3

(2017) Yongxin Yu et al.   Stem Cell Reports

STAT3 signaling drives EZH2 transcriptional activation and mediates poor prognosis in gastric cancer

(2016) Yuan-Ming Pan et al.   Molecular Cancer

Snail2/Slug cooperates with Polycomb repressive complex 2 (PRC2) to regulate neural crest development

(2015) C.-L. Tien et al.   DEVELOPMENT

STAT3-driven transcription depends upon the dimethylation of K49 by EZH2

(2015) Maupali Dasgupta et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Specification of anteroposterior axis by combinatorial signaling during Xenopus development

(2015) Clémence Carron et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors

(2014) T. Zhang et al.   DEVELOPMENT

Down syndrome cell adhesion molecule is important for early development inXenopus tropicalis

(2014) Heidi D. Morales Diaz   GENESIS

Critical Role for Lysine 685 in Gene Expression Mediated by Transcription Factor Unphosphorylated STAT3

(2014) Maupali Dasgupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT3 Target Genes Relevant to Human Cancers

(2014) Richard Carpenter et al.   Cancers

Phosphorylation of EZH2 Activates STAT3 Signaling via STAT3 Methylation and Promotes Tumorigenicity of Glioblastoma Stem-like Cells

(2013) Eunhee Kim et al.   CANCER CELL

Regulation of STAT signaling by acetylation

(2013) Shougang Zhuang   CELLULAR SIGNALLING

Polycomb repressive complex PRC2 regulates Xenopus retina development downstream of Wnt/ -catenin signaling

(2013) I. Aldiri et al.   DEVELOPMENT

The Xenopus homologue of Down syndrome critical region protein 6 drives dorsoanterior gene expression and embryonic axis formation by antagonising polycomb group proteins

(2013) H.-Y. Li et al.   DEVELOPMENT

Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity

(2013) Karin J. Ferrari et al.   MOLECULAR CELL

PRC2 directly methylates GATA4 and represses its transcriptional activity

(2012) A. He et al.   GENES & DEVELOPMENT

Down's-syndrome-related kinase Dyrk1A modulates the p120-catenin-Kaiso trajectory of the Wnt signaling pathway

(2012) J. Y. Hong et al.   JOURNAL OF CELL SCIENCE

High mobility group B proteins regulate mesoderm formation and dorsoventral patterning during zebrafish and Xenopus early development

(2012) Jian-Meng Cao et al.   MECHANISMS OF DEVELOPMENT

EZH2 Generates a Methyl Degron that Is Recognized by the DCAF1/DDB1/CUL4 E3 Ubiquitin Ligase Complex

(2012) Ji Min Lee et al.   MOLECULAR CELL

EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent

(2012) K. Xu et al.   SCIENCE

The Polycomb complex PRC2 and its mark in life

(2011) Raphaël Margueron et al.   NATURE

Lysine methylation of promoter-bound transcription factors and relevance to cancer

(2010) George R Stark et al.   CELL RESEARCH

Geminin cooperates with Polycomb to restrain multi-lineage commitment in the early embryo

(2010) J.-W. Lim et al.   DEVELOPMENT

The RNA-binding protein Seb4/RBM24 is a direct target of MyoD and is required for myogenesis during Xenopus early development

(2010) Hong-Yan Li et al.   MECHANISMS OF DEVELOPMENT

Reversible methylation of promoter-bound STAT3 by histone-modifying enzymes

(2010) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Jarid2/Jumonji Coordinates Control of PRC2 Enzymatic Activity and Target Gene Occupancy in Pluripotent Cells

(2009) Jamy C. Peng et al.   CELL

Down syndrome critical region protein 5 regulates membrane localization of Wnt receptors, Dishevelled stability and convergent extension in vertebrate embryos

(2009) M. Shao et al.   DEVELOPMENT

Self-regulation of Stat3 activity coordinates cell-cycle progression and neural crest specification

(2009) Massimo Nichane et al.   EMBO JOURNAL

Lineage-Specific Polycomb Targets and De Novo DNA Methylation Define Restriction and Potential of Neuronal Progenitors

(2008) Fabio Mohn et al.   MOLECULAR CELL