Alternatives to allogeneic platelet transfusion

Mortality from trauma haemorrhage and opportunities for improvement in transfusion practice

(2016) S. J. Stanworth et al.   BRITISH JOURNAL OF SURGERY

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial

(2016) M Irem Baharoglu et al.   LANCET

Comprehensive review of platelet storage methods for use in the treatment of active hemorrhage

(2016) Elissa M. Milford et al.   TRANSFUSION

Bioenergetic profiling of platelet mitochondria during storage: 4°C storage extends platelet mitochondrial function and viability

(2016) James A. Bynum et al.   TRANSFUSION

Platelets regulate vascular endothelial stability: assessing the storage lesion and donor variability of apheresis platelets

(2016) Gyulnar Baimukanova et al.   TRANSFUSION

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

(2016) Thomas Moreau et al.   Nature Communications

Platelet transfusions in platelet consumptive disorders are associated with arterial thrombosis and in-hospital mortality

(2015) R. Goel et al.   BLOOD

British Committee for Standards in Haematology Guidelines on the Identification and Management of Pre-Operative Anaemia

(2015) Alwyn Kotzé et al.   BRITISH JOURNAL OF HAEMATOLOGY

Microparticle analysis in disorders of hemostasis and thrombosis

(2015) Micah J. Mooberry et al.   CYTOMETRY PART A

Risk of bleeding and use of platelet transfusions in patients with hematologic malignancies: recurrent event analysis

(2015) S. J. Stanworth et al.   HAEMATOLOGICA

CLIP (cryopreserved vs. liquid platelets for surgical bleeding): Protocol for a randomised controlled trial

(2015) Alistair Royse et al.   Heart Lung and Circulation

Autologous Stem-Cell Transplantation Without Hematopoietic Support for the Treatment of Hematologic Malignancies in Jehovah's Witnesses

(2015) Patricia A. Ford et al.   JOURNAL OF CLINICAL ONCOLOGY

Blocking neutrophil diapedesis prevents hemorrhage during thrombocytopenia

(2015) Carina Hillgruber et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Viscoelastic measurements of platelet function, not fibrinogen function, predicts sensitivity to tissue-type plasminogen activator in trauma patients

(2015) H. B. Moore et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Restrictive versus liberal blood transfusion for acute upper gastrointestinal bleeding (TRIGGER): a pragmatic, open-label, cluster randomised feasibility trial

(2015) Vipul Jairath et al.   LANCET

Liberal or Restrictive Transfusion after Cardiac Surgery

(2015) Gavin J. Murphy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Blood transfusion: summary of NICE guidance

(2015) S. Padhi et al.   BMJ-British Medical Journal

Blood transfusion: summary of NICE guidance

(2015) S. Padhi et al.   BMJ-British Medical Journal

Risk of bleeding and use of platelet transfusions in patients with hematologic malignancies: recurrent event analysis

(2015) S. J. Stanworth et al.   HAEMATOLOGICA

Engineered Trehalose Permeable to Mammalian Cells

(2015) Alireza Abazari et al.   PLoS One

Pre-operative anaemia

(2014) B. Clevenger et al.   ANAESTHESIA

Recombinant Human Factor VIIa for Alveolar Hemorrhage Following Allogeneic Stem Cell Transplantation

(2014) Jason M. Elinoff et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Functional factor XIII-A is exposed on the stimulated platelet surface

(2014) J. L. Mitchell et al.   BLOOD

Desmopressin in treatment of haematological disorders and in prevention of surgical bleeding

(2014) Peter J. Svensson et al.   BLOOD REVIEWS

Safety and efficacy of thrombopoietin-receptor agonists in myelodysplastic syndromes: a systematic review and meta-analysis of randomized controlled trials

(2014) Anca Prica et al.   BRITISH JOURNAL OF HAEMATOLOGY

Plasmin Cleavage of von Willebrand Factor as an Emergency Bypass for ADAMTS13 Deficiency in Thrombotic Microangiopathy

(2014) Claudia Tersteeg et al.   CIRCULATION

Anti-VCAM-1 SAINT-O-Somes enable endothelial-specific delivery of siRNA and downregulation of inflammatory genes in activated endothelium in vivo

(2014) Piotr S. Kowalski et al.   JOURNAL OF CONTROLLED RELEASE

Fibrinogen and platelet contributions to clot formation

(2014) Lucy Z. Kornblith et al.   Journal of Trauma and Acute Care Surgery

Complement activation-related pseudoallergy: A stress reaction in blood triggered by nanomedicines and biologicals

(2014) Janos Szebeni   MOLECULAR IMMUNOLOGY

Lower versus Higher Hemoglobin Threshold for Transfusion in Septic Shock

(2014) Lars B. Holst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intravenously administered nanoparticles increase survival following blast trauma

(2014) M. M. Lashof-Sullivan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular microparticle and thrombogram phenotypes in the Prospective Observational Multicenter Major Trauma Transfusion (PROMMTT) Study: Correlation with coagulopathy

(2014) Nena Matijevic et al.   THROMBOSIS RESEARCH

Impact of prophylactic platelet transfusions on bleeding events in patients with hematologic malignancies: a subgroup analysis of a randomized trial (CME)

(2014) Simon J. Stanworth et al.   TRANSFUSION

Treatment with fibrinogen γ-chain peptide-coated, adenosine 5′-diphosphate-encapsulated liposomes as an infusible hemostatic agent against active liver bleeding in rabbits with acute thrombocytopenia

(2014) Kohsuke Hagisawa et al.   TRANSFUSION

The hemostatic activity of cryopreserved platelets is mediated by phosphatidylserine-expressing platelets and platelet microparticles

(2014) Lacey Johnson et al.   TRANSFUSION

Where did platelets go in 2012? A survey of platelet transfusion practice in the North of England

(2014) A. Charlton et al.   TRANSFUSION MEDICINE

Review of In Vivo Studies of Dimethyl Sulfoxide Cryopreserved Platelets

(2014) Sherrill J. Slichter et al.   TRANSFUSION MEDICINE REVIEWS

Hematocrit and flow rate regulate the adhesion of platelets to von Willebrand factor

(2013) Hsieh Chen et al.   Biomicrofluidics

Red blood cells mediate the onset of thrombosis in the ferric chloride murine model

(2013) J. D. Barr et al.   BLOOD

Eltrombopag restores trilineage hematopoiesis in refractory severe aplastic anemia that can be sustained on discontinuation of drug

(2013) R. Desmond et al.   BLOOD

Antifibrinolytic agents in current anaesthetic practice

(2013) E Ortmann et al.   BRITISH JOURNAL OF ANAESTHESIA

Eltrombopag Increases Platelet Numbers in Thrombocytopenic Patients With HCV Infection and Cirrhosis, Allowing for Effective Antiviral Therapy

(2013) Nezam H. Afdhal et al.   GASTROENTEROLOGY

Efficacy and safety of recombinant factor XIII on reducing blood transfusions in cardiac surgery: A randomized, placebo-controlled, multicenter clinical trial

(2013) Keyvan Karkouti et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Intravenous hemostats: challenges in translation to patients

(2013) Margaret Lashof-Sullivan et al.   Nanoscale

A No-Prophylaxis Platelet-Transfusion Strategy for Hematologic Cancers

(2013) Simon J. Stanworth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transfusion Strategies for Acute Upper Gastrointestinal Bleeding

(2013) Càndid Villanueva et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hemostatic Function of Apheresis Platelets Stored at 4°C and 22°C

(2013) Kristin M. Reddoch et al.   SHOCK

Thrombosomes: a platelet-derived hemostatic agent for control of noncompressible hemorrhage

(2013) G. Michael Fitzpatrick et al.   TRANSFUSION

Primary hemostatic capacity of whole blood: a comprehensive analysis of pathogen reduction and refrigeration effects over time

(2013) Heather F. Pidcoke et al.   TRANSFUSION

2012 Update to The Society of Thoracic Surgeons Guideline on Use of Antiplatelet Drugs in Patients Having Cardiac and Noncardiac Operations

(2012) Victor A. Ferraris et al.   ANNALS OF THORACIC SURGERY

Approaches to synthetic platelet analogs

(2012) Christa L. Modery-Pawlowski et al.   BIOMATERIALS

Prothrombin activation in blood coagulation: the erythrocyte contribution to thrombin generation

(2012) M. F. Whelihan et al.   BLOOD

Recombinant factor XIII: a safe and novel treatment for congenital factor XIII deficiency

(2012) A. Inbal et al.   BLOOD

Combination of recombinant factor VIIa and fibrinogen corrects clot formation in primary immune thrombocytopenia at very low platelet counts

(2012) Ole H. Larsen et al.   BRITISH JOURNAL OF HAEMATOLOGY

Guideline on the management of bleeding in patients on antithrombotic agents

(2012) Mike Makris et al.   BRITISH JOURNAL OF HAEMATOLOGY

Plasmin as a proinflammatory cell activator

(2012) T. Syrovets et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Platelet transfusion for reversal of dual antiplatelet therapy in patients requiring urgent surgery: a pilot study

(2012) T. THIELE et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Reversal of the anti-platelet effects of aspirin and clopidogrel

(2012) C. LI et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A randomized controlled trial evaluating recovery and survival of 6% dimethyl sulfoxide-frozen autologous platelets in healthy volunteers

(2012) Larry J. Dumont et al.   TRANSFUSION

Effect of tranexamic acid on surgical bleeding: systematic review and cumulative meta-analysis

(2012) K. Ker et al.   BMJ-British Medical Journal

Lytic Resistance of Fibrin Containing Red Blood Cells

(2011) Nikolett Wohner et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The antifibrinolytic function of factor XIII is exclusively expressed through  2-antiplasmin cross-linking

(2011) S. R. Fraser et al.   BLOOD

Platelet apoptosis by cold-induced glycoprotein Ibα clustering

(2010) D. E. VAN DER WAL et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial

(2010)   LANCET

Intranasal Desmopressin Versus Blood Transfusion in Cirrhotic Patients With Coagulopathy Undergoing Dental Extraction: A Randomized Controlled Trial

(2009) Carmen M. Stanca et al.   JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY

Evaluation of lyophilized platelets as an infusible hemostatic agent in experimental non-compressible hemorrhage in swine

(2009) J. S. HAWKSWORTH et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Intravenous Hemostat: Nanotechnology to Halt Bleeding

(2009) J. P. Bertram et al.   Science Translational Medicine

Novel and unexpected clearance mechanisms for cold platelets

(2009) Viktoria Rumjantseva et al.   TRANSFUSION AND APHERESIS SCIENCE

Blutgerinnungsfaktor-XIII-Substitution bei akuter Leukämie: Ergebnisse einer randomisierten und kontrollierten Studie*

(2008) H. Rasche et al.   DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT

Development of fibrinogen γ-chain peptide-coated, adenosine diphosphate-encapsulated liposomes as a synthetic platelet substitute

(2008) Y. OKAMURA et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Control of Endothelial Targeting and Intracellular Delivery of Therapeutic Enzymes by Modulating the Size and Shape of ICAM-1-targeted Carriers

(2008) Silvia Muro et al.   MOLECULAR THERAPY

Apheresis donors and platelet function: inherent platelet responsiveness influences platelet quality

(2008) Stephen F. Garner et al.   TRANSFUSION

The Coagulopathy of Trauma: A Review of Mechanisms

(2008) John R. Hess et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Preconditions of Hemostasis in Trauma: A Review. The Influence of Acidosis, Hypocalcemia, Anemia, and Hypothermia on Functional Hemostasis in Trauma

(2008) Heiko Lier et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Correction of the Bleeding Time With Lyophilized Platelet Infusions in Dogs on Cardiopulmonary Bypass

(2007) Arthur P. Bode et al.   CLINICAL AND APPLIED THROMBOSIS-HEMOSTASIS