Alveolar-Capillary Membrane-Related Pulmonary Cells as a Target in Endotoxin-Induced Acute Lung Injury

Endothelial cell-cell adhesion and signaling

(2017) Camilla Cerutti et al.   EXPERIMENTAL CELL RESEARCH

Low concentration of oleic acid exacerbates LPS-induced cell death and inflammation in human alveolar epithelial cells

(2017) Altug Kucukgul et al.   EXPERIMENTAL LUNG RESEARCH

The P2X7 Receptor in Infection and Inflammation

(2017) Francesco Di Virgilio et al.   IMMUNITY

Site-specific and endothelial-mediated dysfunction of the alveolar-capillary barrier in response to lipopolysaccharides

(2017) Harshavardhan Janga et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Apoptosis and surfactant protein-C expression inhibition induced by lipopolysaccharide in AEC II cell may associate with NF-κB pathway

(2017) Jinle Lin et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

LPS enhances TLR4 expression and IFN-γ production via the TLR4/IRAK/NF-κB signaling pathway in rat pulmonary arterial smooth muscle cells

(2017) Pengyan Wang et al.   Molecular Medicine Reports

Porphyromonas gingivalis lipopolysaccharides act exclusively through TLR4 with a resilience between mouse and human

(2017) Brice Nativel et al.   Scientific Reports

Lung morphometry: the link between structure and function

(2016) Ewald R. Weibel   CELL AND TISSUE RESEARCH

Safety and Tolerability of Alveolar Type II Cell Transplantation in Idiopathic Pulmonary Fibrosis

(2016) Anna Serrano-Mollar et al.   CHEST

Antimicrobial Peptides and Innate Lung Defenses

(2016) Pieter S. Hiemstra et al.   CHEST

Surfactant proteins A and D are related to severity of the disease, pathogenic bacteria and comorbidity in patients with chronic rhinosinusitis with and without nasal polyps

(2016) B. Uhliarova et al.   CLINICAL OTOLARYNGOLOGY

Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype

(2016) James Ross Cooper et al.   PLoS One

Divergent fibroblast growth factor signaling pathways in lung fibroblast subsets: where do we go from here?

(2015) Jordi Ruiz-Camp et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

The lung communication network

(2015) Davide Losa et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Lipopolysaccharide Induces Alveolar Macrophage Necrosis via CD14 and the P2X7 Receptor Leading to Interleukin-1α Release

(2015) Jargalsaikhan Dagvadorj et al.   IMMUNITY

Plasticity of Hopx+ type I alveolar cells to regenerate type II cells in the lung

(2015) Rajan Jain et al.   Nature Communications

Structure-function relationships in pulmonary surfactant membranes: From biophysics to therapy

(2014) Elena Lopez-Rodriguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling

(2014) Agnieszka Płóciennikowska et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

RAGE/NF-κB Pathway Mediates Lipopolysaccharide-Induced Inflammation in Alveolar Type I Epithelial Cells Isolated from Neonate Rats

(2014) Yuhong Li et al.   INFLAMMATION

Macrophage Dysfunction and Susceptibility to Pulmonary Pseudomonas aeruginosa Infection in Surfactant Protein C-Deficient Mice

(2014) S. W. Glasser et al.   JOURNAL OF IMMUNOLOGY

Pulmonary Surfactant Protein A Regulates TLR Expression and Activity in Human Macrophages

(2014) L. N. Henning et al.   JOURNAL OF IMMUNOLOGY

Interleukin-6 Modulation of Intestinal Epithelial Tight Junction Permeability Is Mediated by JNK Pathway Activation of Claudin-2 Gene

(2014) Rana Al-Sadi et al.   PLoS One

Fibrosis of two: Epithelial cell-fibroblast interactions in pulmonary fibrosis

(2013) Norihiko Sakai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

On the essentiality of lipopolysaccharide to Gram-negative bacteria

(2013) Ge Zhang et al.   CURRENT OPINION IN MICROBIOLOGY

Pulmonary surfactant protein A-induced changes in the molecular conformation of bacterial deep-rough LPS lead to reduced activity on human macrophages

(2013) Susanne P Keese et al.   Innate Immunity

Alveolar macrophage phagocytic activity is enhanced with LPS priming, and combined stimulation of LPS and lipoteichoic acid synergistically induce pro-inflammatory cytokines in pigs

(2013) Mohammad Ariful Islam et al.   Innate Immunity

Alveolar epithelial cells: Master regulators of lung homeostasis

(2013) Loïc Guillot et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Differential effects of insulin and dexamethasone on pulmonary surfactant-associated genes and proteins in A549 and H441 cells and lung tissue

(2013) ZDENEK RUCKA et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

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(2013) Frederic Reynier et al.   MOLECULAR MEDICINE

Differential Response of Primary Alveolar Type I and Type II Cells to LPS Stimulation

(2013) Mandi H. Wong et al.   PLoS One

Liposomal Lipopolysaccharide Initiates TRIF-Dependent Signaling Pathway Independent of CD14

(2013) Sachiko Watanabe et al.   PLoS One

Cytoplasmic LPS Activates Caspase-11: Implications in TLR4-Independent Endotoxic Shock

(2013) J. A. Hagar et al.   SCIENCE

Role of CD14 in host protection against infections and in metabolism regulation

(2013) Ivan Zanoni et al.   Frontiers in Cellular and Infection Microbiology

P2X7 Receptors: Channels, Pores and More

(2012) C. Volonte et al.   CNS & Neurological Disorders-Drug Targets

Type I Alveolar Epithelial Cells Mount Innate Immune Responses during Pneumococcal Pneumonia

(2012) K. Yamamoto et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide Induces Lung Fibroblast Proliferation through Toll-Like Receptor 4 Signaling and the Phosphoinositide3-Kinase-Akt Pathway

(2012) Zhengyu He et al.   PLoS One

Expression of Toll-like receptors and downstream genes in lipopolysaccharide-induced porcine alveolar macrophages

(2012) Mohammad Ariful Islam et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

HIF and the Lung

(2011) Larissa A. Shimoda et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung Fibrosis

(2011) Michael A. Gibbons et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

LPS-Stimulated Cytokine Production in Type I Cells Is Modulated by the Renin–Angiotensin System

(2011) Mandi H. Wong et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Bacterial Lipopolysaccharide Promotes Destabilization of Lung Surfactant-Like Films

(2011) Olga Cañadas et al.   BIOPHYSICAL JOURNAL

CD14 Controls the LPS-Induced Endocytosis of Toll-like Receptor 4

(2011) Ivan Zanoni et al.   CELL

Ion transporting proteins of human bronchial epithelium

(2011) Renata Toczyłowska-Mamińska et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Macrophages in Allergic Asthma: Fine-Tuning Their Pro- and Anti-Inflammatory Actions for Disease Resolution

(2011) Ana Paula Moreira et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Innate Immune Responses to Bacterial Ligands in the Peripheral Human Lung – Role of Alveolar Epithelial TLR Expression and Signalling

(2011) Andrew J. Thorley et al.   PLoS One

C terminus of the P2X7 receptor: treasure hunting

(2011) Helio Miranda Costa-Junior et al.   Purinergic Signalling

Lipopolysaccharide-induced lung injury: Role of P2X7 receptor

(2011) Leonardo C. Monção-Ribeiro et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Acute Lung Injury: How Macrophages Orchestrate Resolution of Inflammation and Tissue Repair

(2011) Susanne Herold et al.   Frontiers in Immunology

Epithelial repair mechanisms in the lung

(2010) Lynn M. Crosby et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Lipopolysaccharide induces apoptotic insults to human alveolar epithelial A549 cells through reactive oxygen species-mediated activation of an intrinsic mitochondrion-dependent pathway

(2010) Chi-Yuan Chuang et al.   ARCHIVES OF TOXICOLOGY

Assessment of Cell Line Models of Primary Human Cells by Raman Spectral Phenotyping

(2010) Robin J. Swain et al.   BIOPHYSICAL JOURNAL

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Lipopolysaccharide inhibits macrophage phagocytosis of apoptotic neutrophils by regulating the production of tumour necrosis factor α and growth arrest-specific gene 6

(2010) Xueying Feng et al.   IMMUNOLOGY

Acute Lung Injury: Epidemiology, Pathogenesis, and Treatment

(2010) Elizabeth R. Johnson et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Immune and Inflammatory Mechanisms of Atherosclerosis

(2009) Elena Galkina et al.   Annual Review of Immunology

Toll-like receptor 4 mediates lipopolysaccharide-induced collagen secretion by phosphoinositide3-kinase-akt pathway in fibroblasts during acute lung injury

(2009) ZhengYu He et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

The structural basis of lipopolysaccharide recognition by the TLR4–MD-2 complex

(2009) Beom Seok Park et al.   NATURE

MOLECULAR MECHANISMS OF PROPOFOL-INVOLVED SUPPRESSION OF NO BIOSYNTHESIS AND INDUCIBLE iNOS GENE EXPRESSION IN LPS-STIMULATED MACROPHAGE-LIKE RAW 264.7 CELLS

(2009) Chao-Jen Lee et al.   SHOCK

Molecular mechanisms of lipopolysaccharide-caused induction of surfactant protein-A gene expression in human alveolar epithelial A549 cells

(2009) Chi-Yuan Chuang et al.   TOXICOLOGY LETTERS

Acute lung injury and cell death: how many ways can cells die?

(2008) Peter S. Tang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Lung Inflammation Induced by Lipoteichoic Acid or Lipopolysaccharide in Humans

(2008) Jacobien J. Hoogerwerf et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Attenuation of Bleomycin-Induced Lung Fibrosis by Oxymatrine Is Associated with Regulation of Fibroblast Proliferation and Collagen Production in Primary Culture

(2008) Xiaohong Chen et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

SP-A Permeabilizes Lipopolysaccharide Membranes by Forming Protein Aggregates that Extract Lipids from the Membrane

(2008) Olga Cañadas et al.   BIOPHYSICAL JOURNAL

TLRs and innate immunity

(2008) B. A. Beutler   BLOOD

Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

(2008) Yumiko Imai et al.   CELL

Synthetic Pulmonary Surfactant Preparations: New Developments and Future Trends

(2008) Ismael Mingarro et al.   CURRENT MEDICINAL CHEMISTRY

Protective role of the lung collectins surfactant protein A and surfactant protein D in airway inflammation

(2008) Angela Haczku   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis

(2008) Hong Xia et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A critical function for CD200 in lung immune homeostasis and the severity of influenza infection

(2008) Robert J Snelgrove et al.   NATURE IMMUNOLOGY

Recognition of Heptoses and the Inner Core of Bacterial Lipopolysaccharides by Surfactant Protein D†

(2007) Hua Wang et al.   BIOCHEMISTRY