Intrathecal Injection in a Rat Model: A Potential Route to Deliver Human Wharton’s Jelly-Derived Mesenchymal Stem Cells into the Brain

Mesenchymal Stem Cells: A Potential Therapeutic Approach for Amyotrophic Lateral Sclerosis?

(2019) Agnese Gugliandolo et al.   Stem Cells International

Cerebrospinal fluid from Alzheimer’s disease patients as an optimal formulation for therapeutic application of mesenchymal stem cells in Alzheimer’s disease

(2019) Jeongmin Lee et al.   Scientific Reports

Intrathecal cell therapy with autologous stromal cells increases cerebral glucose metabolism and can offer a new approach to the treatment of Alzheimer's type dementia

(2019) JESÚS VAQUERO et al.   CYTOTHERAPY

Safety and Feasibility of Repeated Intrathecal Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells in Patients with Neurological Diseases

(2019) Kuang Pan et al.   Stem Cells International

Fate of nanoparticles in the central nervous system after intrathecal injection in healthy mice

(2019) K. T. Householder et al.   Scientific Reports

The Effect of Human Mesenchymal Stem Cells Derived from Wharton’s Jelly in Spinal Cord Injury Treatment Is Dose-Dependent and Can Be Facilitated by Repeated Application

(2018) Petr Krupa et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Safety and tracking of intrathecal allogeneic mesenchymal stem cell transplantation in healthy and diseased horses

(2018) Danielle Jaqueta Barberini et al.   Stem Cell Research & Therapy

Intrathecal Injection of Allogenic Bone Marrow-Derived Mesenchymal Stromal Cells in Treatment of Patients with Severe Ischemic Stroke: Study Protocol for a Randomized Controlled Observer-Blinded Trial

(2018) Lingna Deng et al.   Translational Stroke Research

In vivo distribution of U87MG cells injected into the lateral ventricle of rats with spinal cord injury

(2018) Jeong-Seob Won et al.   PLoS One

Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer’s Disease Model

(2017) Na Kyung Lee et al.   Scientific Reports

CSF, blood-brain barrier, and brain drug delivery

(2016) William M. Pardridge   Expert Opinion on Drug Delivery

From blood–brain barrier to blood–brain interface: new opportunities for CNS drug delivery

(2016) William A. Banks   NATURE REVIEWS DRUG DISCOVERY

Distribution of human umbilical cord blood–derived mesenchymal stem cells (hUCB-MSCs) in canines after intracerebroventricular injection

(2016) Sang Eon Park et al.   NEUROBIOLOGY OF AGING

Distribution of human umbilical cord blood-derived mesenchymal stem cells in the Alzheimer’s disease transgenic mouse after a single intravenous injection

(2016) Sang Eon Park et al.   NEUROREPORT

Intra-Arterially Delivered Mesenchymal Stem Cells Are Not Detected in the Brain Parenchyma in an Alzheimer’s Disease Mouse Model

(2016) Na Kyung Lee et al.   PLoS One

GDF-15 Secreted from Human Umbilical Cord Blood Mesenchymal Stem Cells Delivered Through the Cerebrospinal Fluid Promotes Hippocampal Neurogenesis and Synaptic Activity in an Alzheimer's Disease Model

(2015) Dong Hyun Kim et al.   STEM CELLS AND DEVELOPMENT

Phase I Trial of Repeated Intrathecal Autologous Bone Marrow-Derived Mesenchymal Stromal Cells in Amyotrophic Lateral Sclerosis

(2015) Ki-Wook Oh et al.   Stem Cells Translational Medicine

Human Mesenchymal Stem Cells Modulate Inflammatory Cytokines after Spinal Cord Injury in Rat

(2014) Lucia Urdzíková et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

From Blood to the Brain: Can Systemically Transplanted Mesenchymal Stem Cells Cross the Blood-Brain Barrier?

(2013) Linan Liu et al.   Stem Cells International

Possible induction of acute disseminated encephalomyelitis (ADEM)-like demyelinating illness by intrathecal mesenchymal stem cell injection

(2012) Nirmeen A. Kishk et al.   JOURNAL OF CLINICAL NEUROSCIENCE

CNS Penetration of Intrathecal-Lumbar Idursulfase in the Monkey, Dog and Mouse: Implications for Neurological Outcomes of Lysosomal Storage Disorder

(2012) Pericles Calias et al.   PLoS One

Autologous Mesenchymal Stem Cell Therapy in Progressive Multiple Sclerosis: An Open Label Study

(2012) Mandana Mohyeddin Bonab et al.   Current Stem Cell Research & Therapy

Soluble intracellular adhesion molecule-1 secreted by human umbilical cord blood-derived mesenchymal stem cell reduces amyloid-β plaques

(2011) J-Y Kim et al.   CELL DEATH AND DIFFERENTIATION

The MSC: An Injury Drugstore

(2011) Arnold I. Caplan et al.   Cell Stem Cell

Direct and Indirect Contribution of Human Embryonic Stem Cell–Derived Hepatocyte-Like Cells to Liver Repair in Mice

(2011) Dong–Hun Woo et al.   GASTROENTEROLOGY

Safety and Immunological Effects of Mesenchymal Stem Cell Transplantation in Patients With Multiple Sclerosis and Amyotrophic Lateral Sclerosis

(2010) Dimitrios Karussis et al.   ARCHIVES OF NEUROLOGY

Teratomas from pluripotent stem cells: A clinical hurdle

(2010) Chui-Yee Fong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: A pilot study

(2010) Bassem Yamout et al.   JOURNAL OF NEUROIMMUNOLOGY

Repetitive Intrathecal Catheter Delivery of Bone Marrow Mesenchymal Stromal Cells Improves Functional Recovery in a Rat Model of Contusive Spinal Cord Injury

(2010) Dasa Cizkova et al.   JOURNAL OF NEUROTRAUMA

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Dose-dependent efficacy of ALS-human mesenchymal stem cells transplantation into cisterna magna in SOD1-G93A ALS mice

(2009) Heejaung Kim et al.   NEUROSCIENCE LETTERS

Deconstructing Stem Cell Tumorigenicity: A Roadmap to Safe Regenerative Medicine

(2009) Paul S. Knoepfler   STEM CELLS

Taking stem cells to the clinic: Major challenges

(2008) Ariff Bongso et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo

(2008) Evert Kroon et al.   NATURE BIOTECHNOLOGY