Mice Lacking the Matrilin Family of Extracellular Matrix Proteins Develop Mild Skeletal Abnormalities and Are Susceptible to Age-Associated Osteoarthritis

Aggrecan Hypomorphism Compromises Articular Cartilage Biomechanical Properties and Is Associated with Increased Incidence of Spontaneous Osteoarthritis

(2019) Paolo Alberton et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Osteoarthritis Severely Decreases the Elasticity and Hardness of Knee Joint Cartilage: A Nanoindentation Study

(2019) Mieloch et al.   Journal of Clinical Medicine

Downregulation of microRNA-448 inhibits IL-1β-induced cartilage degradation in human chondrocytes via upregulation of matrilin-3

(2018) Hao Yang et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Detecting Genetics Modifiers of Spondyloepimetaphyseal Dysplasia with Joint Laxity (SEMDJL) in the Caucasian Afrikaner community

(2018) Emile R Chimusa et al.   HUMAN MOLECULAR GENETICS

Targeted proteomics of hip articular cartilage in OA and fracture patients

(2018) Shahrzad Hosseininia et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Extracellular Distribution of Collagen II and Perifibrillar Adapter Proteins in Healthy and Osteoarthritic Human Knee Joint Cartilage

(2017) Sara Firner et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Intra-articular Delivery of Antago-miR-483-5p Inhibits Osteoarthritis by Modulating Matrilin 3 and Tissue Inhibitor of Metalloproteinase 2

(2017) Hua Wang et al.   MOLECULAR THERAPY

Forced exercise-induced osteoarthritis is attenuated in mice lacking the small leucine-rich proteoglycan decorin

(2016) Tobias Gronau et al.   ANNALS OF THE RHEUMATIC DISEASES

Extracellular matrix protein Matrilin-4 regulates stress-induced HSC proliferation via CXCR4

(2016) Hannah Uckelmann et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Early changes in morphology, bone mineral density and matrix composition of vertebrae lead to disc degeneration in aged collagen IX −/− mice

(2016) Matthias Kamper et al.   MATRIX BIOLOGY

Structural and mechanical properties of the proliferative zone of the developing murine growth plate cartilage assessed by atomic force microscopy

(2016) Carina Prein et al.   MATRIX BIOLOGY

Deficient Mechanical Activation of Anabolic Transcripts and Post-Traumatic Cartilage Degeneration in Matrilin-1 Knockout Mice

(2016) Yupeng Chen et al.   PLoS One

Insights into osteoarthritis progression revealed by analyses of both knee tibiofemoral compartments

(2015) C.-H. Chou et al.   OSTEOARTHRITIS AND CARTILAGE

Matrilin-3 Chondrodysplasia Mutations Cause Attenuated Chondrogenesis, Premature Hypertrophy and Aberrant Response to TGF-β in Chondroprogenitor Cells

(2014) Chathuraka Jayasuriya et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Matrilin-3 Inhibits Chondrocyte Hypertrophy as a Bone Morphogenetic Protein-2 Antagonist

(2014) Xu Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Matrilin-2 Is a Widely Distributed Extracellular Matrix Protein and a Potential Biomarker in the Early Stage of Osteoarthritis in Articular Cartilage

(2014) Shukun Zhang et al.   Biomed Research International

Comparative Proteomic Analysis of Normal and Collagen IX Null Mouse Cartilage Reveals Altered Extracellular Matrix Composition and Novel Components of the Collagen IX Interactome

(2013) Bent Brachvogel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The matrilin-3 VWA1 domain modulates interleukin-6 release from primary human chondrocytes

(2013) A.R. Klatt et al.   OSTEOARTHRITIS AND CARTILAGE

Loss of NAC1 Expression Is Associated with Defective Bony Patterning in the Murine Vertebral Axis

(2013) Kai Lee Yap et al.   PLoS One

Matrilin-3 switches from anti- to pro-anabolic upon integration to the extracellular matrix

(2012) Jean-Baptiste Vincourt et al.   MATRIX BIOLOGY

Matrilin-3 Induction of IL-1 receptor antagonist Is required for up-regulating collagen II and aggrecan and down-regulating ADAMTS-5 gene expression

(2012) Chathuraka T Jayasuriya et al.   ARTHRITIS RESEARCH & THERAPY

Loss of matrilin 1 does not exacerbate the skeletal phenotype in a mouse model of multiple epiphyseal dysplasia caused by a Matn3 V194D mutation

(2011) Peter A. Bell et al.   ARTHRITIS AND RHEUMATISM

An unfolded protein response is the initial cellular response to the expression of mutant matrilin-3 in a mouse model of multiple epiphyseal dysplasia

(2010) Seema Nundlall et al.   CELL STRESS & CHAPERONES

The matrilins: Modulators of extracellular matrix assembly

(2010) Andreas R. Klatt et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Polymorphisms in the Matrilin-1 Gene and Risk of Mandibular Prognathism in Koreans

(2010) J.Y. Jang et al.   JOURNAL OF DENTAL RESEARCH

Mouse Gestation Length Is Genetically Determined

(2010) Stephen A. Murray et al.   PLoS One

Combined role of type IX collagen and cartilage oligomeric matrix protein in cartilage matrix assembly: Cartilage oligomeric matrix protein counteracts type IX collagen–induced limitation of cartilage collagen fibril growth in mouse chondrocyte cultures

(2009) K. Blumbach et al.   ARTHRITIS AND RHEUMATISM

Cartilage and Bone Extracellular Matrix

(2009) Chiara Gentili/snm et al.   CURRENT PHARMACEUTICAL DESIGN

Matrilin-3 activates the expression of osteoarthritis-associated genes in primary human chondrocytes

(2009) Andreas R. Klatt et al.   FEBS LETTERS

The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration

(2009) D. Malin et al.   JOURNAL OF CELL SCIENCE

Increased expression of matrilin-3 not only in osteoarthritic articular cartilage but also in cartilage-forming tumors, and down-regulation of SOX9 via epidermal growth factor domain 1-dependent signaling

(2008) Jean-Baptiste Vincourt et al.   ARTHRITIS AND RHEUMATISM

The Role of Cartilage Oligomeric Matrix Protein (COMP) in Skeletal Disease

(2008) K. Posey et al.   CURRENT DRUG TARGETS

Collagen IX-deficiency seriously compromises growth cartilage development in mice

(2008) R DREIER et al.   MATRIX BIOLOGY

Enhancing and maintaining chondrogenesis of synovial fibroblasts by cartilage extracellular matrix protein matrilins

(2008) M. Pei et al.   OSTEOARTHRITIS AND CARTILAGE

Ablation of collagen IX and COMP disrupts epiphyseal cartilage architecture

(2007) K BLUMBACH et al.   MATRIX BIOLOGY