An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients

Mitochondrial complex activity in permeabilised cells of chronic fatigue syndrome patients using two cell types

(2019) Cara Tomas et al.   PeerJ

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Comprehensive Review

(2019) Mateo Cortes Rivera et al.   Diagnostics

Assessing cellular energy dysfunction in CFS/ME using a commercially available laboratory test

(2019) Cara Tomas et al.   Scientific Reports

Myalgic encephalomyelitis/chronic fatigue syndrome patients exhibit altered T cell metabolism and cytokine associations

(2019) Alexandra H. Mandarano et al.   JOURNAL OF CLINICAL INVESTIGATION

Reduced glycolytic reserve in isolated natural killer cells from Myalgic encephalomyelitis/chronic fatigue syndrome patients: A preliminary investigation

(2018)   ASIAN PACIFIC JOURNAL OF ALLERGY AND IMMUNOLOGY

Pharmacological activation of AMPK and glucose uptake in cultured human skeletal muscle cells from patients with ME/CFS

(2018) Audrey E. Brown et al.   BIOSCIENCE REPORTS

Weighting of orthostatic intolerance time measurements with standing difficulty score stratifies ME/CFS symptom severity and analyte detection

(2018) Alice M. Richardson et al.   Journal of Translational Medicine

Insights into myalgic encephalomyelitis/chronic fatigue syndrome phenotypes through comprehensive metabolomics

(2018) Dorottya Nagy-Szakal et al.   Scientific Reports

EBV reduces autophagy, intracellular ROS and mitochondria to impair monocyte survival and differentiation

(2018) M.S. Gilardini Montani et al.   Autophagy

Metabolic profiling of a myalgic encephalomyelitis/chronic fatigue syndrome discovery cohort reveals disturbances in fatty acid and lipid metabolism

(2017) Arnaud Germain et al.   Molecular BioSystems

Cellular bioenergetics is impaired in patients with chronic fatigue syndrome

(2017) Cara Tomas et al.   PLoS One

The ATPase Inhibitory Factor 1 (IF1): A master regulator of energy metabolism and of cell survival

(2016) Javier García-Bermúdez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

4E-BP1, a multifactor regulated multifunctional protein

(2016) Xiaoyu Qin et al.   CELL CYCLE

Immortalized Parkinson's disease lymphocytes have enhanced mitochondrial respiratory activity

(2016) Sarah J. Annesley et al.   Disease Models & Mechanisms

Mitochondrial DNA variants correlate with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome

(2016) Paul Billing-Ross et al.   Journal of Translational Medicine

Novel Blood Biomarkers Are Associated with White Matter Lesions in Fragile X- Associated Tremor/Ataxia Syndrome

(2016) Danuta Z. Loesch et al.   Neurodegenerative Diseases

Metabolic features of chronic fatigue syndrome

(2016) Robert K. Naviaux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A systems study reveals concurrent activation of AMPK and mTOR by amino acids

(2016) Piero Dalle Pezze et al.   Nature Communications

Genome-wide association analysis identifies genetic variations in subjects with myalgic encephalomyelitis/chronic fatigue syndrome

(2016) K A Schlauch et al.   Translational Psychiatry

Bottom-up proteomics suggests an association between differential expression of mitochondrial proteins and chronic fatigue syndrome

(2016) F Ciregia et al.   Translational Psychiatry

mTOR coordinates protein synthesis, mitochondrial activity and proliferation

(2015) Masahiro Morita et al.   CELL CYCLE

Metabolic profiling reveals anomalous energy metabolism and oxidative stress pathways in chronic fatigue syndrome patients

(2015) Christopher W. Armstrong et al.   Metabolomics

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Neuroinflammation: Ways in Which the Immune System Affects the Brain

(2015) Richard M. Ransohoff et al.   Neurotherapeutics

Abnormalities of AMPK Activation and Glucose Uptake in Cultured Skeletal Muscle Cells from Individuals with Chronic Fatigue Syndrome

(2015) Audrey E. Brown et al.   PLoS One

The Opposing Actions of Target of Rapamycin and AMP-Activated Protein Kinase in Cell Growth Control

(2015) Sravanth K. Hindupur et al.   Cold Spring Harbor Perspectives in Biology

miR-14 Regulates Autophagy during Developmental Cell Death by Targeting ip3-kinase 2

(2014) Charles Nelson et al.   MOLECULAR CELL

Mitochondrial dysfunctions in Myalgic Encephalomyelitis / chronic fatigue syndrome explained by activated immuno-inflammatory, oxidative and nitrosative stress pathways

(2013) Gerwyn Morris et al.   METABOLIC BRAIN DISEASE

The B cell transcription program mediates hypomethylation and overexpression of key genes in Epstein-Barr virus-associated proliferative conversion

(2013) Henar Hernando et al.   GENOME BIOLOGY

Investigation of the freely available easy-to-use software ‘EZR’ for medical statistics

(2012) Y Kanda   BONE MARROW TRANSPLANTATION

Target of Rapamycin (TOR) in Nutrient Signaling and Growth Control

(2011) Robbie Loewith et al.   GENETICS

Myalgic encephalomyelitis: International Consensus Criteria

(2011) B. M. Carruthers et al.   JOURNAL OF INTERNAL MEDICINE

Mitochondrial enzymes discriminate between mitochondrial disorders and chronic fatigue syndrome

(2011) Bart Smits et al.   MITOCHONDRION

AMP-activated protein kinase: nature's energy sensor

(2011) David Carling et al.   Nature Chemical Biology

AMP-activated protein kinase (AMPK)  1 2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise

(2011) H. M. O'Neill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E

(2010) Andrew C. Hsieh et al.   CANCER CELL

4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in Tumors

(2010) Qing-Bai She et al.   CANCER CELL

Patients with chronic fatigue syndrome performed worse than controls in a controlled repeated exercise study despite a normal oxidative phosphorylation capacity

(2010) Ruud CW Vermeulen et al.   Journal of Translational Medicine

mTORC1-Mediated Cell Proliferation, But Not Cell Growth, Controlled by the 4E-BPs

(2010) R. J. O. Dowling et al.   SCIENCE

Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dye

(2010) Meav-Lang J Lay et al.   Virology Journal

IF1, the endogenous regulator of the F1Fo-ATPsynthase, defines mitochondrial volume fraction in HeLa cells by regulating autophagy

(2009) Michelangelo Campanella et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Utility of lymphoblastoid cell lines

(2009) L. Sie et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Molecular mechanisms of mTOR-mediated translational control

(2009) Xiaoju Max Ma et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Replicative aging down-regulates the myogenic regulatory factors in human myoblasts

(2008) Anne Bigot et al.   BIOLOGY OF THE CELL