Cryptotanshinone from the Salvia miltiorrhiza Bunge Attenuates Ethanol-Induced Liver Injury by Activation of AMPK/SIRT1 and Nrf2 Signaling Pathways

Salvia Miltiorrhiza Ameliorates Liver Fibrosis by Activating Hepatic Natural Killer Cells in Vivo and in Vitro

(2018) Yuan Peng et al.   Frontiers in Pharmacology

Alcohol inhibits T-cell glucose metabolism and hepatitis in ALDH2-deficient mice and humans: roles of acetaldehyde and glucocorticoids

(2018) Yanhang Gao et al.   GUT

Gomisin N Alleviates Ethanol-Induced Liver Injury through Ameliorating Lipid Metabolism and Oxidative Stress

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Sirt1: Role Under the Condition of Ischemia/Hypoxia

(2016) Xiaofei Meng et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Rutin ameliorates diabetic neuropathy by lowering plasma glucose and decreasing oxidative stress via Nrf2 signaling pathway in rats

(2016) Ruifeng Tian et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Dioscin alleviates BDL- and DMN-induced hepatic fibrosis via Sirt1/Nrf2-mediated inhibition of p38 MAPK pathway

(2016) Lina Gu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nuclear transcription factor Nrf2 suppresses prostate cancer cells growth and migration through upregulating ferroportin

(2016) Dong Xue et al.   Oncotarget

Characteristics and Antioxidant Effect of Garlic in the Fermentation of Cheonggukjang by Bacillus amyloliquefaciens MJ1-4

(2016) Jeong Hwan Kim et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Melatonin Upregulates the Activity of AMPK and Attenuates Lipid Accumulation in Alcohol-induced Rats

(2015) Bei-bei Rui et al.   ALCOHOL AND ALCOHOLISM

Hepatoprotective effect of mulberry water extracts on ethanol-induced liver injury via anti-inflammation and inhibition of lipogenesis in C57BL/6J mice

(2013) Chang-Chieh Tang et al.   FOOD AND CHEMICAL TOXICOLOGY

Mouse model of chronic and binge ethanol feeding (the NIAAA model)

(2013) Adeline Bertola et al.   Nature Protocols

Suppression of acute ethanol-induced hepatic steatosis by docosahexaenoic acid is associated with downregulation of stearoyl-CoA desaturase 1 and inflammatory cytokines

(2013) Li-Li Huang et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

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Role of Nrf2 in preventing ethanol-induced oxidative stress and lipid accumulation

(2012) Kai Connie Wu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Alcoholic Liver Disease: Pathogenesis and New Therapeutic Targets

(2011) Bin Gao et al.   GASTROENTEROLOGY

Cryptotanshinone inhibits LPS-induced proinflammatory mediators via TLR4 and TAK1 signaling pathway

(2011) Xin Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Dynamics of Nrf2 and Keap1 in ARE-MediatedNQO1Expression by Wasabi 6-(Methylsulfinyl)hexyl Isothiocyanate

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Activation of peroxisome proliferator activated receptor alpha ameliorates ethanol induced steatohepatitis in mice

(2011) Lingbo Kong et al.   Lipids in Health and Disease

Alcoholic liver disease: pathogenesis and new targets for therapy

(2011) José Altamirano et al.   Nature Reviews Gastroenterology & Hepatology

Interleukin-22 treatment ameliorates alcoholic liver injury in a murine model of chronic-binge ethanol feeding: Role of signal transducer and activator of transcription 3

(2010) Sung Hwan Ki et al.   HEPATOLOGY

Cryptotanshinone Suppressed Inflammatory Cytokines Secretion in RAW264.7 Macrophages through Inhibition of the NF-κB and MAPK Signaling Pathways

(2010) Shu Tang et al.   INFLAMMATION

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

Protective effects of saponins from the root of Platycodon grandiflorum against fatty liver in chronic ethanol feeding via the activation of AMP-dependent protein kinase

(2009) Tilak Khanal et al.   FOOD AND CHEMICAL TOXICOLOGY

Ethanol-induced liver injury and changes in sulfur amino acid metabolomics in glutathione peroxidase and catalase double knockout mice

(2009) Sun J. Kim et al.   JOURNAL OF HEPATOLOGY

AMPK in Health and Disease

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Effects of tanshinone IIA on the hepatotoxicity and gene expression involved in alcoholic liver disease

(2008) Hu-Quan Yin et al.   ARCHIVES OF PHARMACAL RESEARCH

Salvia miltiorrhiza Bunge and its active component cryptotanshinone protects primary cultured rat hepatocytes from acute ethanol-induced cytotoxicity and fatty infiltration

(2008) Hu-Quan Yin et al.   FOOD AND CHEMICAL TOXICOLOGY

Nuclear Factor-Eythroid 2–Related Factor 2 Prevents Alcohol-Induced Fulminant Liver Injury

(2008) Jutta Lamlé et al.   GASTROENTEROLOGY

Cytochrome P450 2E1 contributes to ethanol-induced fatty liver in mice

(2008) Yongke Lu et al.   HEPATOLOGY

SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1

(2008) Fan Lan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase

(2008) Xiuyun Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model

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