Animal Models of Chronic Cerebral Hypoperfusion: From Mouse to Primate

Chronic cerebral hypoperfusion shifts the equilibrium of amyloid β oligomers to aggregation-prone species with higher molecular weight

(2019) Taro Bannai et al.   Scientific Reports

Asymptomatic carotid stenosis is associated with mobility and cognitive dysfunction and heightens falls in older adults

(2019) Vicki L. Gray et al.   JOURNAL OF VASCULAR SURGERY

The pathology and pathophysiology of vascular dementia

(2018) Raj N. Kalaria   NEUROPHARMACOLOGY

Dementia and Atrial Fibrillation: Pathophysiological Mechanisms and Therapeutic Implications

(2018) Romain Chopard et al.   AMERICAN JOURNAL OF MEDICINE

Limb Ischemic Conditioning Improved Cognitive Deficits via eNOS-Dependent Augmentation of Angiogenesis after Chronic Cerebral Hypoperfusion in Rats

(2018) Changhong Ren et al.   Aging and Disease

High Systolic Blood Pressure Induces Cerebral Microvascular Endothelial Dysfunction, Neurovascular Unit Damage, and Cognitive Decline in Mice

(2018) Olivia de Montgolfier et al.   HYPERTENSION

A mouse model of subcortical vascular dementia reflecting degeneration of cerebral white matter and microcirculation

(2017) Eek-Sung Lee et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

The effects of environmental enrichment on white matter pathology in a mouse model of chronic cerebral hypoperfusion

(2017) Yoshiki Hase et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion

(2017) Yoshiki Hase et al.   Journal of Neuroinflammation

Focal Solute Trapping and Global Glymphatic Pathway Impairment in a Murine Model of Multiple Microinfarcts

(2017) Minghuan Wang et al.   JOURNAL OF NEUROSCIENCE

Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion

(2017) Akihiro Kitamura et al.   Scientific Reports

Neuropathological diagnosis of vascular cognitive impairment and vascular dementia with implications for Alzheimer’s disease

(2016) Raj N. Kalaria   ACTA NEUROPATHOLOGICA

Vascular cognitive impairment and dementia

(2016) Philip B. Gorelick et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Vascular cognitive impairment: Modeling a critical neurologic disease in vitro and in vivo

(2016) Alex M. Helman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cilostazol reduces blood brain barrier dysfunction, white matter lesion formation and motor deficits following chronic cerebral hypoperfusion

(2016) Hamidreza Edrissi et al.   BRAIN RESEARCH

Animal Models of Vascular Cognitive Impairment and Dementia (VCID)

(2016) Jennifer Gooch et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Heart failure and risk of dementia: a Danish nationwide population-based cohort study

(2016) Kasper Adelborg et al.   EUROPEAN JOURNAL OF HEART FAILURE

Strong Impact of Chronic Cerebral Hypoperfusion on Neurovascular Unit, Cerebrovascular Remodeling, and Neurovascular Trophic Coupling in Alzheimer’s Disease Model Mouse

(2016) Jingwei Shang et al.   JOURNAL OF ALZHEIMERS DISEASE

Vascular Contributions to Cognitive Impairment and Dementia

(2016) Jeremy B. Madigan et al.   STROKE

Substantial Reduction of Parenchymal Cerebral Blood Flow in Mice with Bilateral Common Carotid Artery Stenosis

(2016) Yorito Hattori et al.   Scientific Reports

Rodent Models of Vascular Cognitive Impairment

(2016) Yi Yang et al.   Translational Stroke Research

Chronic cerebral hypoperfusion enhances Tau hyperphosphorylation and reduces autophagy in Alzheimer’s disease mice

(2016) Lifeng Qiu et al.   Scientific Reports

Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia

(2015) Aiqing Chen et al.   BRAIN

Models and mechanisms of vascular dementia

(2015) Poornima Venkat et al.   EXPERIMENTAL NEUROLOGY

A Novel Mouse Model of Subcortical Infarcts with Dementia

(2015) Y. Hattori et al.   JOURNAL OF NEUROSCIENCE

Vascular dementia

(2015) John T O'Brien et al.   LANCET

Hippocampal volume and shape in pure subcortical vascular dementia

(2015) Geon Ha Kim et al.   NEUROBIOLOGY OF AGING

Physical activity, motor function, and white matter hyperintensity burden in healthy older adults

(2015) D. A. Fleischman et al.   NEUROLOGY

Adrenomedullin promotes differentiation of oligodendrocyte precursor cells into myelin-basic-protein expressing oligodendrocytes under pathological conditions in vitro

(2015) Takakuni Maki et al.   Stem Cell Research

Association Between Atrial Fibrillation and Dementia in the General Population

(2015) Renée F. A. G. de Bruijn et al.   JAMA Neurology

Bilateral Common Carotid Artery Occlusion in the Rat as a Model of Retinal Ischaemia

(2014) Yingxiang Huang et al.   NEURO-OPHTHALMOLOGY

Silent Information Regulator 2 Homolog 1 Counters Cerebral Hypoperfusion Injury by Deacetylating Endothelial Nitric Oxide Synthase

(2014) Yorito Hattori et al.   STROKE

An MRI-Histological Study of White Matter in Stroke-Free SHRSP

(2013) John F Brittain et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Mouse Models to Study the Effect of Cardiovascular Risk Factors on Brain Structure and Cognition

(2013) Diewertje I Bink et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Proximal Cerebral Arteries Develop Myogenic Responsiveness in Heart Failure via Tumor Necrosis Factor-α–Dependent Activation of Sphingosine-1-Phosphate Signaling

(2012) Jingli Yang et al.   CIRCULATION

Hypertension Induces Brain β-Amyloid Accumulation, Cognitive Impairment, and Memory Deterioration Through Activation of Receptor for Advanced Glycation End Products in Brain Vasculature

(2012) Daniela Carnevale et al.   HYPERTENSION

Carotid artery disease and cognitive impairment

(2012) Vida Demarin et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Vascular dementia

(2012) Amos D. Korczyn et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Cerebral amyloid β(42) deposits and microvascular pathology in ageing baboons

(2011) M. Ndung'u et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

The Influence of Chronic Cerebral Hypoperfusion on Cognitive Function and Amyloid β Metabolism in APP Overexpressing Mice

(2011) Mahito Yamada et al.   PLoS One

Vascular Contributions to Cognitive Impairment and Dementia

(2011) Philip B. Gorelick et al.   STROKE

Angiogenic and Vasoprotective Effects of Adrenomedullin on Prevention of Cognitive Decline After Chronic Cerebral Hypoperfusion in Mice

(2011) Takakuni Maki et al.   STROKE

Pre-treatment of adrenomedullin suppresses cerebral edema caused by transient focal cerebral ischemia in rats detected by magnetic resonance imaging

(2010) Takashi Kondoh et al.   BRAIN RESEARCH BULLETIN

Experimental models of vascular dementia and vascular cognitive impairment: a systematic review

(2010) Nadim S. Jiwa et al.   JOURNAL OF NEUROCHEMISTRY

Role of neuroinflammation in hypertension-induced brain amyloid pathology

(2010) Daniela Carnevale et al.   NEUROBIOLOGY OF AGING

Nonhypotensive Dose of Telmisartan Attenuates Cognitive Impairment Partially Due to Peroxisome Proliferator-Activated Receptor-γ Activation in Mice With Chronic Cerebral Hypoperfusion

(2010) Kazuo Washida et al.   STROKE

Early Protective Effect of Bone Marrow Mononuclear Cells Against Ischemic White Matter Damage Through Augmentation of Cerebral Blood Flow

(2010) Youshi Fujita et al.   STROKE

A Mouse Model Characterizing Features of Vascular Dementia With Hippocampal Atrophy

(2010) Keiko Nishio et al.   STROKE

Do in vivo Experimental Models Reflect Human Cerebral Small Vessel Disease? a Systematic Review

(2008) Atticus H Hainsworth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Incidence and survival of dementia in a general population of Japanese elderly: the Hisayama study

(2008) Y Matsui et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY