Article
Nutrition & Dietetics
Run-Yang Zhang, Jing-Hao Gao, Yi-Lin Shi, Yi-Fei Lan, Hua-Min Liu, Wen-Xue Zhu, Xue-De Wang
Summary: In this study, sesame hull polysaccharides (SHP) were successfully extracted using ultrasound-assisted alkali extraction methods. Three purified polysaccharide fractions were obtained, with SHP-2 being the dominant fraction. It was found that SHP-2 had a high yield and contained various types of polysaccharides. This study provides useful basic data for the development of applications for sesame seed hull polysaccharides in the food and pharmaceutical industries.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Guoyong Yu, Jing Zhao, Yunlu Wei, Linlin Huang, Fei Li, Yu Zhang, Quanhong Li
Summary: In this study, subcritical water (SCW) was used to modify pumpkin polysaccharides, leading to changes in rheological and emulsifying properties. Different treatment temperatures resulted in variations in molecular weight distribution and enhanced antioxidant activity. The results demonstrate that SCW treatment is an effective method for improving solution properties and antioxidant activity of pumpkin polysaccharides.
Article
Chemistry, Applied
Shiqiang Wang, Gang Li, Xinfei Zhang, Yuqian Wang, Yi Qiang, Bulei Wang, Jiabin Zou, Junfeng Niu, Zhezhi Wang
Summary: Polysaccharides obtained from Polygonatum sibiricum (PSP) were purified and characterized in this study. The PSP1 sample had the highest content and best solubility. The main sugar residue linkages were identified as 1)-beta-D-Fruf-(2 -> 1)-beta-D-Fruf-(2 -> 1), 1 -> -beta-D-Fruf-(2 -> 6)alpha-D-Glcp (1 ->,-> 4)-beta-D-Manp-(1 -> 4)-beta-D-Manp-(1 -> and -> 6)-beta-D-Glcp-(1 -> 4)-beta-D-Manp-(1 ->. Branch chain analysis revealed the presence of -> 1,6)-beta-D-Fruf-(2 ->, beta-D-Fruf-(2 ->,-> 1,6)-beta-D-Fruf-(2 ->,-> 6)-beta-D-Fruf(2 -> linkages, with the link site at position C-6. In vitro antioxidant activity tests showed that PSP1 had scavenging effects on DPPH, hydroxyl radical, superoxide anion radical, and exhibited a specific chelating ability for ferrous ions. These findings suggest that P. sibiricum polysaccharides may possess potential antioxidant properties.
CARBOHYDRATE POLYMERS
(2022)
Article
Biotechnology & Applied Microbiology
Na Wang, Lumei Dai, Zishuo Chen, Tao Li, Jiayi Wu, Houbo Wu, Hualian Wu, Wenzhou Xiang
Summary: Microalgal polysaccharides, particularly from Rhodosorus sp. SCSIO-45730, were successfully extracted and characterized in terms of physicochemical properties and antioxidant activities. The polysaccharides showed high sulfate and uronic acid content, along with strong scavenging activities, indicating their potential as antioxidants in various industries.
JOURNAL OF APPLIED PHYCOLOGY
(2022)
Article
Food Science & Technology
Hui-Rong Yang, Lian-Hong Chen, Ying-Jie Zeng
Summary: The novel homogeneous polysaccharide extracted from Tricholoma matsutake demonstrated strong antioxidant activity and inhibition on alpha-glucosidase and a-amylase activities. Furthermore, treatment with this polysaccharide significantly improved glucose consumption, glycogen synthesis, and the activities of various enzymes in insulin-resistant-human hepatoma cell line (IR-HepG2), suggesting great potential in managing type 2 diabetes mellitus.
Article
Biochemistry & Molecular Biology
Yingying Liu, Yongjun Kan, Yating Huang, Chang Jiang, Li Zhao, Juan Hu, Wensheng Pang
Summary: This study investigated the physicochemical and antidiabetic characteristics of Pseudostellaria heterophylla polysaccharides (PF40). The results showed that PF40 had an amorphous form and good thermal stability. Experimental studies demonstrated that PF40 could improve insulin resistance symptoms and maintain intestinal immune homeostasis. These findings provide important insights into the structure and antidiabetic properties of Pseudostellaria heterophylla polysaccharides, which may contribute to its industrial development in the future.
Article
Food Science & Technology
Feng Li, Yu Jin, Jun Wang, Huaide Xu
Summary: This study isolated two polysaccharides, MSP1-1 and MSP1-2, from mushrooms of the Morchella genus, and found that they exhibit good thermal stability and antioxidant activity. MSP1-1 is a glucan, while MSP1-2 is a galactomannan with a network structure, which is observed for the first time.
Article
Food Science & Technology
Tingxue Zhao, Qingying Dong, Huabin Zhou, Hailong Yang
Summary: Sargassum fusiforme can be best preserved in terms of nutrients and bioactivity through freeze-drying, and microwave drying shows potential as an alternative method with shorter processing time. However, sun drying and hot air drying result in quality loss, including the loss of pigments and bioactive compounds.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Agricultural Engineering
Yuntao Liu, Daiwen Chen, Xiaoyu Duan, Mingyue Zhang, Cheng Li, Zhiqing Zhang, Bin Hu, Aiping Liu, Qin Li, Hong Chen, Zizhong Tang, Wenjuan Wu, Daiwen Chen
Summary: Polysaccharides (CCPs-1 and CCPs-2) were isolated and purified from Craterellus cornucopioides, containing different molar ratios of sugars. Structural analysis revealed that these polysaccharides were primarily connected by mannose with (1 -> 3)-linked and exhibited significant antioxidant activity, especially cmCCPs-2.
INDUSTRIAL CROPS AND PRODUCTS
(2021)
Article
Chemistry, Applied
Chen Shen, Teng Wang, Feng Guo, Kunlai Sun, Bin Wang, Jie Wang, Zefeng Zhang, Xing Zhang, Yuqin Zhao, Yin Chen
Summary: A novel heteropolysaccharide fraction (SP0.1-1) was isolated from Sea buckthorn berries, with a specific composition and structure. Supplementing with SP0.1-1 extended fruit flies' lifespan, enhanced antioxidant enzyme activities, and reduced oxidative damage, showing potential for sea buckthorn polysaccharide products development.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Multidisciplinary
Heping Hui, Weijun Gao
Summary: Four polysaccharides (BJP50, BJP60, BJP70, and BJP80) were extracted from Herba Patriniae through ethanol precipitation. They exhibited distinct physicochemical characteristics and antioxidant activities, with BJP80 and BJP70 showing higher scavenging capacities for free radicals.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Fabian A. Figueroa, Roberto T. Abdala-Diaz, Claudia Perez, Virginia Casas-Arrojo, Aleksandra Nesic, Cecilia Tapia, Carla Duran, Oscar Valdes, Carolina Parra, Gaston Bravo-Arrepol, Luis Soto, Jose Becerra, Gustavo Cabrera-Barjas
Summary: This study aims to isolate and characterize the polysaccharide fractions from Codium bernabei, a green alga found on Chilean coasts. The extracted fractions were mainly composed of sulfated galactan unit and exhibited antioxidant, anticoagulant, and antitumor activities. The findings suggest the potential biotechnological application of sulfated galactan polysaccharides from Chilean marine resources.
Article
Chemistry, Physical
Fanfan Wang, Shuhong Ye, Yan Ding, Zhiyang Ma, Qike Zhao, Min Zang, Yue Li
Summary: Ginkgo biloba leaves polysaccharide is considered as an important functional factor with an acidic polysaccharide structure, containing various glycosidic linkages, and showing strong antioxidant activities.
JOURNAL OF MOLECULAR STRUCTURE
(2022)
Review
Food Science & Technology
Yin Zhou, Xinxin Chen, Tingting Chen, Xiaoqiang Chen
Summary: This review examines the relationships between the sources, structural properties, and antibacterial activity of plant polysaccharides. The structural features of plant polysaccharides are closely tied to their antibacterial activity, and they can exert antibacterial effects through various mechanisms. This review will guide future applications of plant polysaccharides.
TRENDS IN FOOD SCIENCE & TECHNOLOGY
(2022)
Article
Food Science & Technology
Jingjie Wang, Shuo Shi, Fangfei Li, Xin Du, Baohua Kong, Hao Wang, Xiufang Xia
Summary: This study investigated the physicochemical properties and antioxidant activity of sea cucumber gonadal polysaccharide extracted using enzymatic, ultrasound, and ultrasound-assisted enzymatic methods. The results showed that the polysaccharide extracted by the ultrasound-assisted enzymatic method had higher total sugar and sulfate group content compared to other extraction methods. The antioxidant activity of the ultrasound-assisted enzymatic extracted polysaccharide was also higher in the tested concentration range.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)