Scaling factors for thein vitro-in vivoextrapolation (IV-IVE) of renal drug and xenobiotic glucuronidation clearance

Transcriptional regulation of human UDP-glucuronosyltransferase genes

(2014) Dong Gui Hu et al.   DRUG METABOLISM REVIEWS

Targeted Quantitative Proteomics for the Analysis of 14 UGT1As and -2Bs in Human Liver Using NanoUPLC–MS/MS with Selected Reaction Monitoring

(2013) John K. Fallon et al.   JOURNAL OF PROTEOME RESEARCH

Expression of UGT2B7 is driven by two mutually exclusive promoters and alternative splicing in human tissues

(2013) Vincent Ménard et al.   Pharmacogenetics and Genomics

The influence of kidney function on dapagliflozin exposure, metabolism and pharmacodynamics in healthy subjects and in patients with type 2 diabetes mellitus

(2012) Sreeneeranj Kasichayanula et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Quantification of Human Uridine-Diphosphate Glucuronosyl Transferase 1A Isoforms in Liver, Intestine, and Kidney Using Nanobore Liquid Chromatography–Tandem Mass Spectrometry

(2011) David E. Harbourt et al.   ANALYTICAL CHEMISTRY

Bovine Serum Albumin Decreases Km Values of Human UDP-Glucuronosyltransferases 1A9 and 2B7 and Increases Vmax Values of UGT1A9

(2011) N. Manevski et al.   DRUG METABOLISM AND DISPOSITION

Effects of Ketamine on Human UDP-Glucuronosyltransferases In Vitro Predict Potential Drug-Drug Interactions Arising from Ketamine Inhibition of Codeine and Morphine Glucuronidation

(2011) V. Uchaipichat et al.   DRUG METABOLISM AND DISPOSITION

Characterization of Niflumic Acid as a Selective Inhibitor of Human Liver Microsomal UDP-Glucuronosyltransferase 1A9: Application to the Reaction Phenotyping of Acetaminophen Glucuronidation

(2011) J. O. Miners et al.   DRUG METABOLISM AND DISPOSITION

Quantitative distribution of mRNAs encoding the 19 human UDP-glucuronosyltransferase enzymes in 26 adult and 3 fetal tissues

(2011) Michael H. Court et al.   XENOBIOTICA

Renal cortical and medullary blood flow responses to altered NO availability in humans

(2010) Mads Damkjær et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Renal UDP-glucuronosyltransferases and the glucuronidation of xenobiotics and endogenous mediators

(2010) Kathleen M. Knights et al.   DRUG METABOLISM REVIEWS

Immunohistochemical expression of conjugating UGT1A-derived isoforms in normal and tumoral drug-metabolizing tissues in humans

(2010) Judith Bellemare et al.   JOURNAL OF PATHOLOGY

The prediction of drug-glucuronidation parameters in humans: UDP-glucuronosyltransferase enzyme-selective substrate and inhibitor probes for reaction phenotyping andin vitro–in vivoextrapolation of drug clearance and drug-drug interaction potential

(2009) John O. Miners et al.   DRUG METABOLISM REVIEWS

How is mRNA expression predictive for protein expression? A correlation study on human circulating monocytes

(2008) Yanfang Guo et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

Determination of mRNA Expression of Human UDP-Glucuronosyltransferases and Application for Localization in Various Human Tissues by Real-Time Reverse Transcriptase-Polymerase Chain Reaction

(2008) S. Ohno et al.   DRUG METABOLISM AND DISPOSITION

Expression of UGT1A and UGT2B mRNA in Human Normal Tissues and Various Cell Lines

(2008) A. Nakamura et al.   DRUG METABOLISM AND DISPOSITION

Prediction of Drug Clearance by Glucuronidation from in Vitro Data: Use of Combined Cytochrome P450 and UDP-Glucuronosyltransferase Cofactors in Alamethicin-Activated Human Liver Microsomes

(2008) P. J. Kilford et al.   DRUG METABOLISM AND DISPOSITION

The "Albumin Effect" and Drug Glucuronidation: Bovine Serum Albumin and Fatty Acid-Free Human Serum Albumin Enhance the Glucuronidation of UDP-Glucuronosyltransferase (UGT) 1A9 Substrates but Not UGT1A1 and UGT1A6 Activities

(2008) A. Rowland et al.   DRUG METABOLISM AND DISPOSITION