Review
Immunology
Theo Wirth, Nathalie Balandraud, Laurent Boyer, Pierre Lafforgue, Thao Pham
Summary: PsA diagnosis and treatment is often delayed, resulting in joint damage and disability. Research has identified potential biomarkers to improve PsA diagnosis and prognosis, but further studies are needed to evaluate their performance.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Rheumatology
Wenhui Xie, Hong Huang, Lanlan Ji, Zhuoli Zhang
Summary: Pregnant women with psoriasis and PsA have a higher risk of adverse maternal outcomes, but not adverse neonatal outcomes. Close monitoring of the mothers' clinical status before and during pregnancy is recommended.
Article
Immunology
Weize Gao, Zhan Wang, Wenshuai Li, Yongxin Li, Mingjun Liu
Summary: This review systematically demonstrates the research progress of psoriasis-related biomarkers and elaborates their related mechanisms in the pathological development of psoriasis and psoriatic arthritis. In addition, we summarize the development of biologic therapies for psoriasis and psoriatic arthritis in order to drive the broader discussion of psoriasis as an autoimmune-mediated inflammatory skin disease.
INTERNATIONAL IMMUNOPHARMACOLOGY
(2023)
Review
Medicine, General & Internal
Ailing Zou, Yongjun Chen, Nian Shi, Yu Ye
Summary: Biological therapies may increase the risk of herpes zoster in patients with psoriasis and psoriatic arthritis, especially tumor necrosis factor-alpha inhibitors. Younger age and female gender may be risk factors for developing herpes zoster.
Article
Multidisciplinary Sciences
Hyung Jin Hahn, Sang Gyu Kwak, Dong-Kyu Kim, Jong-Yeup Kim
Summary: Research indicates that individuals with Behcet disease are more likely to develop psoriasis, with higher risk seen in male BD patients and older individuals. Additionally, Behcet disease patients are also more prone to developing psoriatic arthritis.
SCIENTIFIC REPORTS
(2021)
Review
Rheumatology
Aravinthan Loganathan, Narainraj Kamalaraj, Carlos El-Haddad, Kevin Pile
Summary: The prevalence of MetS is significantly higher in PsA populations compared to PsO and RA populations. Patients with PsA are 1.62 times more likely to have MetS compared to PsO populations, and 1.66 times more likely compared to RA populations. Further studies are needed to determine if addressing metabolic components in MetS offers therapeutic benefits in terms of disease activity and cardiovascular health in PsA, RA, and PsO populations.
INTERNATIONAL JOURNAL OF RHEUMATIC DISEASES
(2021)
Article
Psychiatry
Miaolan Guo, Jing Su, Shaoyan Zheng, Baixin Chen
Summary: Psoriasis is associated with poor sleep quality and higher risk for sleep disturbance, especially among patients with psoriatic arthritis, severe psoriasis, shorter duration of psoriasis, and younger age. Patients with psoriasis are also more likely to experience insomnia, restless legs syndrome (RLS), and depression.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2024)
Review
Biochemistry & Molecular Biology
Irmina Olejniczak-Staruch, Magdalena Ciazynska, Dorota Sobolewska-Sztychny, Joanna Narbutt, Malgorzata Skibinska, Aleksandra Lesiak
Summary: Numerous scientific studies have shown significant skin and gut dysbiosis in patients with psoriasis, with changes in abundance of specific bacterial taxa. Treatments for psoriasis have been found to significantly influence skin and gut microbiome, with orally administered probiotics having a positive impact on the course of the disease. Further research is needed to understand the influence of microbiome on the development of inflammatory skin diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Dermatology
Yan Xie, Yang Liu, Yi Liu
Summary: The combination of biologics with methotrexate (MTX) showed better clinical efficiency for treating psoriasis compared to biologic monotherapy, without an increased risk of severe adverse events. However, there was no significant difference in clinical efficiency for the treatment of PsA, indicating a need for further studies to address relevant issues.
DERMATOLOGIC THERAPY
(2021)
Article
Cell Biology
Fridha Viridiana Villalpando-Vargas, Juan Jose Rivera-Valdes, Anabell Alvarado-Navarro, Selene Guadalupe Huerta-Olvera, Jose Macias-Barragan, Erika Martinez-Lopez, Omar Graciano-Machuca
Summary: The T allele and TT genotype of the IL-17F rs763780 polymorphism may be associated with a decreased risk of psoriasis, while other polymorphisms in IL-17A, IL-17F, and IL-17RA showed no association with Ps.
INFLAMMATION RESEARCH
(2021)
Review
Health Care Sciences & Services
Yu-Wen Huang, Jing-Wun Lu, Tai-Li Chen
Summary: Bone health in patients with psoriatic disease has been a focus recently, with studies investigating volumetric bone mineral density (vBMD) using high-resolution peripheral quantitative computed tomography (HR-pQCT). A systematic review and meta-analysis of 780 patients found that those with psoriatic disease had lower average vBMD compared to controls. However, results for trabecular vBMD and cortical vBMD were inconclusive due to small sample sizes. Further research is needed to clarify the relationship between psoriasis and bone microstructure.
Article
Public, Environmental & Occupational Health
Holly R. Harris, Karen Moreno Nascimento Korkes, Tricia Li, Marina Kvaskoff, Eunyoung Cho, Luiz Fernando Carvalho, Abrar A. Qureshi, Mauricio Abrao, Stacey A. Missmer
Summary: A bidirectional association between endometriosis and psoriasis with PsA was found in this study. Psoriasis with concomitant PsA was associated with a higher risk of laparoscopically confirmed endometriosis, while the diagnosis of endometriosis was suggestive of subsequent risk of psoriasis with PsA.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2022)
Review
Medicine, General & Internal
Fei Qi, Yaqi Tan, Amin Yao, Xutong Yang, Yanling He
Summary: Psoriatic disease is a spectrum of diseases affecting both skin and musculoskeletal features, with a considerable number of patients progressing from cutaneous psoriasis to psoriatic arthritis. The use of proteomics technologies provides a unique opportunity to explore potential biomarkers for psoriatic arthritis.
FRONTIERS IN MEDICINE
(2021)
Article
Medicine, General & Internal
Ningyuan Liu, Danni Su, Keshuai Liu, Binbin Liu, Shibo Wang, Xiaoyan Zhang
Summary: This study aims to synthesize current evidence on the impact of IL-17/IL-17R inhibitors on atherosclerosis in PSO and PSA, providing updated evidence to evaluate the effectiveness of IL-17/IL-17R inhibitors as a solution to atherosclerosis in comorbidity with PSO and PSA.
Article
Immunology
Guillaume Larid, Adriana Delwail, Thomas Dalle, Philippe Vasseur, Christine Silvain, Jean-Francois Jegou, Franck Morel, Jean-Claude Lecron, Elisabeth Gervais
Summary: Psoriatic arthritis (PsA) and cutaneous psoriasis (PsO) exhibit distinct cytokine production profiles, which are influenced by clinical phenotype and metabolic syndrome.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Medical Laboratory Technology
Jorge Hernandez-Bello, Miroslaba Rodriguez-Puente, Jorge Gutierrez-Cuevas, Samuel Garcia-Arellano, Jose Francisco Munoz-Valle, Mary Fafutis-Morris, Delfina Guadalupe Villanueva-Quintero, Anabell Alvarado-Navarro
Summary: The study found significant differences in genotypic and allelic frequencies for the MIF -173 G>C polymorphism, with carriers of the GC genotype and the C allele having higher odds of developing PP. The 6C haplotype was also associated with increased PP risk, and the -173 CC genotype was linked to elevated MIF serum levels.
JOURNAL OF CLINICAL LABORATORY ANALYSIS
(2021)
Article
Cell Biology
Fridha Viridiana Villalpando-Vargas, Juan Jose Rivera-Valdes, Anabell Alvarado-Navarro, Selene Guadalupe Huerta-Olvera, Jose Macias-Barragan, Erika Martinez-Lopez, Omar Graciano-Machuca
Summary: The T allele and TT genotype of the IL-17F rs763780 polymorphism may be associated with a decreased risk of psoriasis, while other polymorphisms in IL-17A, IL-17F, and IL-17RA showed no association with Ps.
INFLAMMATION RESEARCH
(2021)
Article
Pharmacology & Pharmacy
M. J. Bermudez-Guzman, J. M. Jimenez-Vargas, L. D. Possani, F. Zamudio, G. Orozco-Gutierrez, E. Oceguera-Contreras, J. N. Enriquez-Vara, O. F. Vazquez-Vuelvas, P. E. Garcia-Villalvazo, L. L. Valdez-Velazquez
Summary: The venom of the scorpion Centruroides tecomanus contains two new peptides, Ct-IT1 and Ct-IT2, which are toxic to insects. These peptides have a high toxicity to crickets, causing paralysis even in small amounts. The relative abundance of these peptides in the venom is also significant. The comparison of their molecular masses and N-terminal sequences revealed similarities with peptides from other scorpion venoms. Additionally, the 3D structure analysis showed similarities with known insect toxins from scorpions. These findings suggest that Ct-IT1 and CtIT2 toxins have the potential to be used as a biological control method for pests that affect economically important crops.
Article
Engineering, Environmental
Eden Oceguera-Contreras, Oscar Aguilar-Juarez, David Oseguera-Galindo, Jose Macias-Barragan, Gerardo Ortiz-Torres, Maria Luisa Pita-Lopez, Jorge Dominguez, Igor Titov, Amine Kamen
Summary: This study established the optimal operational conditions for hydrogen production using vermicomposting-tea and sugarcane molasses as substrate, providing guidance for pilot and industrial-scale operations.
Article
Medicine, General & Internal
Karen Pesqueda-Cendejas, Isela Parra-Rojas, Paulina E. Mora-Garcia, Margarita Montoya-Buelna, Adolfo Ruiz-Ballesteros, Monica R. Meza-Meza, Bertha Campos-Lopez, Melissa Rivera-Escoto, Barbara Vizmanos-Lamotte, Sergio Cerpa-Cruz, Ulises de la Cruz-Mosso
Summary: This study found that high levels of C-reactive protein (CRP) were associated with increased cardiometabolic risk and clinical disease activity in systemic lupus erythematosus (SLE) patients.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Chemistry, Applied
Jesse Y. Rumbo Morales, Gerardo Ortiz-Torres, Rodolfo Omar Dominguez Garcia, Carlos Alberto Torres Cantero, Manuela Calixto Rodriguez, Estela Sarmiento-Bustos, Eden Oceguera-Contreras, Alberto Arturo Flores Hernandez, Julio Cesar Rodriguez Cerda, Yehoshua Aguilar Molina, Mario Martinez Garcia
Summary: This article focuses on the production and purification of compounds such as bioethanol, biohydrogen, medical oxygen, and biomethane through the Pressure Swing Adsorption (PSA) process. By studying different adsorbents, PSA configurations, and relevant variables, it is possible to achieve high-purity biofuel production.
ADSORPTION SCIENCE & TECHNOLOGY
(2022)
Article
Genetics & Heredity
Monica R. Meza-Meza, Barbara Vizmanos, Melissa Rivera-Escoto, Adolfo Ruiz-Ballesteros, Karen Pesqueda-Cendejas, Isela Parra-Rojas, Margarita Montoya-Buelna, Sonia Luquin, Bertha Campos-Lopez, Paulina E. Mora-Garcia, Sergio Cerpa-Cruz, Ulises De la Cruz-Mosso
Summary: The study found that the TT FokI VDR genotype is associated with high VDR expression and clinical disease activity in systemic lupus erythematosus patients.
Article
Rheumatology
Karen Pesqueda-Cendejas, Isela Parra-Rojas, Monica R. Meza-Meza, Paulina E. Mora-Garcia, Bertha Campos-Lopez, Adolfo Ruiz-Ballesteros, Margarita Montoya-Buelna, Melissa Rivera-Escoto, Jose M. Moreno-Ortiz, Luis A. Bautista-Herrera, Sergio Cerpa-Cruz, Ulises De la Cruz-Mosso
Summary: The -717 A>G CRP polymorphism is associated with high CRP levels and high CVD risk in Mexican-mestizo SLE patients.
CLINICAL RHEUMATOLOGY
(2023)
Review
Nutrition & Dietetics
Karen Pesqueda-Cendejas, Melissa Rivera-Escoto, Monica R. Meza-Meza, Bertha Campos-Lopez, Isela Parra-Rojas, Margarita Montoya-Buelna, Ulises de la Cruz-mosso
Summary: Systemic lupus erythematosus (SLE) is characterized by a bimodal mortality pattern related to clinical disease activity and cardiovascular disease (CVD). The high prevalence of CVD in SLE patients is believed to be caused by the complex interaction between traditional and non-traditional CVD risk factors. Additionally, nutritional approaches have the potential to reduce SLE severity and organ damage by modulating the development of CVD risk factors.
Article
Medicine, Research & Experimental
Jose Alvaro Lomeli-Nieto, Jose Francisco Munoz-Valle, Jose Eduardo Navarro-Zarza, Christian Johana Banos-Hernandez, Samuel Garcia-Arellano, Anabell Alvarado-Navarro, Brian Uriel Anaya-Macias, Edith Oregon-Romero, Carlos Eduardo Fuentes-Baez, Isela Parra-Rojas, Jorge Hernandez-Bello
Summary: Systemic Sclerosis (SSc), a chronic autoimmune disease, is characterized by immune disorder, microvascular damage, and fibrosis. This study found that the variants +869T > C and +915G > C in the TGFB1 gene are associated with an increased risk of SSc in the Southern Mexican population. Furthermore, these genetic variants were shown to result in lower mRNA expression of TGFB1.
CLINICAL AND EXPERIMENTAL MEDICINE
(2023)
Review
Immunology
Jose Macias-Barragan, Margarita Montoya-Buelna, Moises Enciso-Vargas, Liliana Alvarado-Ruiz, Eden Oceguera-Contreras, Aracely Suggey Guerra-Renteria, Omar Graciano-Machuca
Summary: This meta-analysis study found a significant association between the KIR2DS1 gene and susceptibility to psoriasis, while the KIR2DS4 and 3DL1 genes were found to be protective against psoriasis.
IMMUNOLOGICAL INVESTIGATIONS
(2022)
