Review
Pharmacology & Pharmacy
Hui Zhao, Ya-Long Feng, Ming Wang, Jing-Jing Wang, Tian Liu, Jun Yu
Summary: Angelica dahurica root is a well-known edible medicinal herb in China. It contains numerous active compounds, including coumarins and volatile oils. Modern pharmacological studies have shown that the root of A. dahurica and its active components have various bioactivities, such as anti-inflammatory, anti-tumor, anti-oxidant, analgesic, and effects on the cardiovascular system and neuroprotection.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Agricultural Engineering
Liangliang Han, Libo Zhang, Yuedong He, Lijing Liao, Junde Li, Sheng Xu, Yucheng Zhao, Xiaohong Bian, Yuanzheng Xia
Summary: As a popular medicinal plant, Angelica dahurica has garnered attention in herbal medicine due to its active compounds, furanocoumarins (FCs), which have antioxidant, anti-tumor, and anti-virus activities. However, the enzymes responsible for the biosynthesis of FCs have not been identified. This study screened six prenyltransferase-coding sequences and identified two C-PTs (AdPT1, 2) and one O-PT (AdPT3) that are involved in the conversion of different compounds. The study also conducted structural analysis and mutagenesis experiments, revealing important amino acids for the activity of AdPT1. This study provides insights into the biosynthetic pathways of FCs in A. dahurica for further evolutionary studies.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Biochemistry & Molecular Biology
Dong Ryun Gu, Hyun Yang, Seong Cheol Kim, Youn-Hwan Hwang, Hyunil Ha
Summary: Angelica dahurica radix has traditional use in China and Korea for treating headaches, cold-damp pain, and skin diseases. This study found that the water extract of Angelica dahurica radix effectively inhibits osteoclast differentiation and alleviates bone loss.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Fisheries
Yihang Liu, Xiaopin Tan, Yiling Zhang, Fei Ling, Tianqiang Liu, Gaoxue Wang
Summary: The study found that isoimperatorin from Angelica dahurica showed significant efficacy in eradicating Gyrodactylus kobayashii in goldfish, reducing infection prevalence and intensity without causing significant toxicity to the host. Isoimperatorin damaged the tegument of G. kobayashii and disrupted its homeostasis, providing insufficient energy for the parasite, which led to promising anthelmintic effects.
Article
Medicine, General & Internal
Yafang Zhang, Zhehong Li, Junqiang Wei, Lingwei Kong, Mingze Song, Yange Zhang, Xiangyu Xiao, Haiying Cao, Yu Jin
Summary: This study investigated the potential mechanism of Angelica dahurica in the treatment of osteosarcoma using network pharmacology and molecular docking methods. The results showed that Angelica dahurica can treat osteosarcoma through multiple targets and pathways, affecting the proliferation, apoptosis, migration, infiltration, and angiogenesis of osteosarcoma. Certain components have the potential to become treatment drugs for osteosarcoma and improve the 5-year survival rate.
Article
Pharmacology & Pharmacy
Yonghui Hu, Sisi Lei, Zhiyue Yan, Zhibo Hu, Jun Guo, Hang Guo, Bei Sun, Congqing Pan
Summary: The study utilized network pharmacology and in vivo validation to investigate how Angelica dahurica promotes faster wound healing in diabetic patients through anti-inflammatory effects, specifically by regulating the polarization of M1 and M2 subtypes of macrophages.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Honglin Wang, Xuelian Wang, Linan Zhou, Shaojie Zhang, Lijun An, Jiahe Bao, Zhengguo Li, Yanjun Sun, Yuhao Li, Jianlin Cui, Da-Qing Jin, Jie Zhang, Jing Xu, Yuanqiang Guo
Summary: ADP80-2, a water-soluble polysaccharide obtained from Angelica dahurica, exhibits immunomodulatory effects by enhancing phagocytosis and nitric oxide production in macrophages. Its discovery holds promise for the development of novel immunomodulatory agents.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Review
Chemistry, Multidisciplinary
Qingquan Wang, Yanan Li, Shengguang Wang, Zedong Xiang, Weichao Dong, Xiaoyu Li, Yumin Wei, Peng Gao, Long Dai
Summary: This review systematically summarizes and evaluates the traditional applications, botany, chemistry, and pharmacology of Angelica dahurica (AD). AD has been extensively used for its medicinal uses, with imperatorin (IMP) as the bioactive compound responsible for its therapeutic effects. AD not only has medical effects but can also be used as food condiments and accessories.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Engineering, Chemical
Zheng Qin, Xinying Li, Lei Yan, Pengle Cheng, Ying Huang
Summary: This paper introduces a deep learning method, YOLOX_am, to address the detection and sorting issues of Angelica dahurica tablets. The proposed model combines the fast detection ability of YOLOX with the feature weighting ability of the attention mechanism, achieving high accuracy and real-time sorting.
JOURNAL OF FOOD PROCESS ENGINEERING
(2023)
Article
Plant Sciences
Rong Huang, Yinrong Liu, Jianling Chen, Zuyu Lu, Jiajia Wang, Wei He, Zhi Chao, Enwei Tian
Summary: This study evaluated the levels of genetic variation and differentiation within and between wild and cultivated populations of Angelica dahurica using microsatellite markers. The results suggest that the domestication process is likely the major factor resulting in the loss of genetic diversity in cultivated populations and in significant genetic differentiation from the wild populations.
Article
Multidisciplinary Sciences
Qinghua Wu, Qi Yan, Lan Jiang, Cuiping Chen, Xulong Huang, Xinglong Zhu, Tao Zhou, Jiang Chen, Jie Yan, Feiyan Wen, Jin Pei
Summary: This study used LC-MS/MS based targeted metabolomics analysis to investigate the effects of freeze-drying and oven-drying on Angelica dahurica. It identified 193 metabolites as key differential metabolites, most of which were upregulated under oven drying. It also found significant changes in the PAL metabolic pathway.
SCIENTIFIC REPORTS
(2023)
Article
Genetics & Heredity
Xiaodong Zhang, Caixia Li, Zhanchao Hao, Yongjiang Liu
Summary: Angelica dahurica roots have a long history of use in traditional Chinese medicine due to their high coumarin content. In this study, transcriptome analysis and weighted gene co-expression network analysis (WGCNA) were used to identify key genes and gene modules involved in coumarin and terpenoid backbone biosynthesis. KEGG enrichment analysis was also conducted to explore crucial pathways in coumarin biosynthesis. The findings provide valuable insights into the biosynthesis of coumarin in A. dahurica, which can facilitate future research and potential applications in traditional Chinese medicine and synthetic biology strategies.
Article
Biochemical Research Methods
Huan Shi, Ya-Qing Chang, Xie Feng, Gui-Ya Yang, Yu-Guang Zheng, Qian Zheng, Lan-Lan Zhang, Dan Zhang, Long Guo
Summary: This study compared the chemical compositions of Angelica dahurica (BZ) and Angelica dahurica var. formosana (HBZ) and identified chemical markers for their discrimination. The results showed that while the chemical compositions of BZ and HBZ were similar, there were significant differences in the contents of bioactive coumarins. Chemometric analysis identified five coumarins that could be used as chemical markers to distinguish the two botanical origins. This study provides valuable information for understanding the chemical differences between BZ and HBZ and offers feasible methods for quality evaluation and discrimination of herbal medicines of multiple botanical sources.
PHYTOCHEMICAL ANALYSIS
(2022)
Article
Integrative & Complementary Medicine
Yuh-Huey Chao, Wan-Ting Yang, Ming-Chang Li, Fwu-Lin Yang, Ru-Ping Lee
Summary: The study indicated that treatment with Angelica dahurica and Rheum officinale could enhance wound healing in diabetic rats by altering the healing pattern toward that of nondiabetic rats.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2021)
Article
Genetics & Heredity
Liqiang Zhao, Shengxiang Zhang, Chunmiao Shan, Yuanyuan Shi, Huan Wu, Jiawen Wu, Daiyin Peng
Summary: This study revealed the transcriptome information of Angelica dahurica and identified key genes related to coumarin biosynthesis. The research laid the foundation for further exploration of this biosynthetic pathway.
Article
Agriculture, Multidisciplinary
Ping Yang, Huanlu Song, Lijin Wang, Hao Jing
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Shang Su, Li-Jin Wang, Jian-Wei Ni, Yong-Hang Geng, Xin-Qiao Xu
CHEMISTRY & BIODIVERSITY
(2020)
Article
Chemistry, Applied
Kunlun Guo, Qiaojun Wang, Tianze Xia, Lijin Wang, Huanlu Song, Lixue Yang
Summary: Odor is a key factor in assessing the quality of beef tallow, and the temperature of smelting directly affects its odor characteristics. By using SPME-GC-O-MS and sensory evaluation, this study investigated the impact of different smelting temperatures (110-160 degrees C) on the formation of odor compounds. A total of 37 odor compounds were identified, with aldehydes being the most abundant. As the smelting temperature increased, the proportion of aldehydes and alcohols increased, while that of acids decreased. Sensory evaluation, as well as the content and number of odor compounds, were highest at 155 degrees C. Through OPLS and OAV analysis, 1-octen-3-ol, (E)-2-octenal, (E)-2-nonenal, and nonanal were found to be the most distinguishable odor compounds at different smelting temperatures.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Chemistry, Applied
Gordon. J. McDougall, Alexandre Foito, Gary Dobson, Ceri Austin, Julie Sungurtas, Shang Su, Lijin Wang, Chengyong Feng, Shanshan Li, Liangsheng Wang, Wei Wei, J. William Allwood, Derek Stewart
Article
Food Science & Technology
Yonghong Ye, Songyan Zheng, Yuanxing Wang
Summary: In this study, the changes of aroma components in Gannan navel orange during growth were systematically studied using HS-SPME-GC-MS. Key aroma components and markers were identified. These findings contribute to a better understanding of the dynamic variation of aroma compounds during navel orange growth and have potential for industrial applications.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Jia Xu, Yayuan Zhang, Mengke Zhang, Xinlin Wei, Yiming Zhou
Summary: This study evaluated the effects of glucosamine selenium on summer-autumn tea, showing that it can enhance nutritional quality, improve sensory characteristics, and increase plant adaptation to environmental changes and abiotic stresses.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Yuanming Chu, Zhaoyang Ding, Jing Xie
Summary: This study investigated the use of ice glazing containing D-sodium erythorbate (DSE) and vacuum packaging to maintain the quality of large yellow croaker during frozen storage. The results showed that vacuum packaging effectively inhibited ice crystal growth and minimized water loss, while the combination of vacuum packaging and 0.3% DSE-infused ice glazing maintained freshness indicators at low levels throughout the 300-day storage period. This combination was considered the most effective in preserving the quality of the fish.
FOOD RESEARCH INTERNATIONAL
(2024)
Review
Food Science & Technology
Md. Ashikur Rahman, Shirin Akter, Md. Ashrafudoulla, Md. Anamul Hasan Chowdhury, A. G. M. Sofi Uddin Mahamud, Si Hong Park, Sang-Do Ha
Summary: This comprehensive review aims to provide insights into the mechanisms and key factors influencing biofilm formation by A. hydrophila in the food industry. It explores the molecular processes involved in various stages of biofilm formation and investigates the impact of intrinsic factors and environmental conditions on biofilm architecture and resilience. The article also highlights the potential of bibliometric analysis in conceptualizing the research landscape and identifying knowledge gaps in A. hydrophila biofilm research.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Chujing Wang, Wenni Tian, Zengliu Song, Qun Wang, Yong Cao, Jie Xiao
Summary: Solid lipid ratio in emulsions has significant effects on colloidal stability, mucus permeability, and bioavailability in vivo. Higher solid lipid ratio improves intestinal stability but reduces mucus permeability.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Dacai Zhong, Liping Kang, Juan Liu, Xiang Li, Li Zhou, Luqi Huang, Zidong Qiu
Summary: In this study, a novel online extraction electrospray ionization mass spectrometry method was developed to comprehensively characterize complex foods. Meanwhile, a characteristic marker screening method and chemometrics modeling were used for the accurate authentication of highly-similar foods. This research has significant implications for ensuring food quality and safety.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Qiannan Zhao, Jinyi Yang, Jiahui Li, Lei Zhang, Xiaohai Yan, Tianli Yue, Yahong Yuan
Summary: This study investigated the transport and hypoglycemic effects of phenolics in mulberry leaves using an in vitro digestion model. The results showed that digested phenolics had higher absorbability and could inhibit glucose digestion and absorption. Phenolics also regulated glucose metabolism. Luteoforol and p-coumaric acid were found to be the primary phenolics strongly correlated with the hypoglycemic ability of mulberry leaves.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Yanyun Cao, Qingling Wang, Jinou Lin, Yin-Yi Ding, Jianzhong Han
Summary: This study investigated the effects of gallic acid (GA) and epigallocatechin gallate (EGCG) at different ratios on the gel properties of calcium induced-whey protein emulsion gel. It was found that GA and EGCG could promote gel formation, increase gel strength, and delay the release of emulsified oil droplets.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Monique Martins Strieder, Vitor Lacerda Sanches, Mauricio Ariel Rostagno
Summary: This study proposed an integrated and automated procedure for extracting, separating, and quantifying bioactive compounds from coffee co-products. By optimizing the extraction, separation, and analysis method, real-time analysis was achieved. The results suggest that coupling different techniques can efficiently extract, separate, and analyze phenolic compounds, providing an integrated method to produce high-added value ingredients for various applications.
FOOD RESEARCH INTERNATIONAL
(2024)
Article
Food Science & Technology
Kyu Sang Sim, Hyoyoung Kim, Suel Hye Hur, Tae Woong Na, Ji Hye Lee, Ho Jin Kim
Summary: Geographical origin plays a crucial role in determining the quality and safety of agricultural products. In this study, ICP analysis was used to determine the inorganic elemental content of onions and identify their geographical origin. Chemometric methods were applied to analyze the ICP results, and the accuracy of distinguishing between Korean and Chinese onions was found to be excellent. The findings suggest that this method can be beneficial for identifying agricultural products.
FOOD RESEARCH INTERNATIONAL
(2024)
