Verteporfin inhibits oxidative phosphorylation and induces cell death specifically in glioma stem cells

AS602801 Sensitizes Ovarian Cancer Stem Cells to Paclitaxel by Down-regulating MDR1

(2019) MASAHIRO YAMAMOTO et al.   ANTICANCER RESEARCH

BMP9 counteracts the tumorigenic and pro-angiogenic potential of glioblastoma

(2018) Elena Porcù et al.   CELL DEATH AND DIFFERENTIATION

AS602801, an Anti-Cancer Stem Cell Drug Candidate, Suppresses Gap-junction Communication Between Lung Cancer Stem Cells and Astrocytes

(2018) KENTA KURAMOTO et al.   ANTICANCER RESEARCH

A Small-molecule Kinase Inhibitor, CEP-1347, Inhibits Survivin Expression and Sensitizes Ovarian Cancer Stem Cells to Paclitaxel

(2018) KEITA TOGASHI et al.   ANTICANCER RESEARCH

Involvement of GLUT1-mediated glucose transport and metabolism in gefitinib resistance of non-small-cell lung cancer cells

(2018) Shuhei Suzuki et al.   Oncotarget

Verteporfin selectively kills hypoxic glioma cells through iron-binding and increased production of reactive oxygen species

(2018) Katherine L. Eales et al.   Scientific Reports

Role of inhibitor of yes-associated protein 1 in triple-negative breast cancer with taxol-based chemoresistance

(2018) Ying Li et al.   CANCER SCIENCE

Verteporfin Inhibits Cell Proliferation and Induces Apoptosis in Human Leukemia NB4 Cells without Light Activation

(2017) Min Chen et al.   International Journal of Medical Sciences

Plasma concentrations of atovaquone given to immunocompromised patients to prevent Pneumocystis jirovecii

(2017) Christine Robin et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antitumor activity of gemcitabine against high-grade meningioma in vitro and in vivo

(2017) Hiroyuki Takeda et al.   Oncotarget

Licochalcone A specifically induces cell death in glioma stem cells via mitochondrial dysfunction

(2017) Kenta Kuramoto et al.   FEBS Open Bio

Verteporfin inhibits growth of human glioma in vitro without light activation

(2017) Ahmad Al-Moujahed et al.   Scientific Reports

Aripiprazole, an Antipsychotic and Partial Dopamine Agonist, Inhibits Cancer Stem Cells and Reverses Chemoresistance

(2016) SHUHEI SUZUKI et al.   ANTICANCER RESEARCH

Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth

(2016) Baoli Hu et al.   CELL

The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo

(2016) Masashi Okada et al.   Oncotarget

IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance

(2016) Amanda L. Rinkenbaugh et al.   Oncotarget

Repurposing atovaquone: Targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells

(2016) Marco Fiorillo et al.   Oncotarget

Mitochondrial diseases

(2016) Gráinne S. Gorman et al.   Nature Reviews Disease Primers

Nutrient deprivation-related OXPHOS/glycolysis interconversion via HIF-1α/C-MYC pathway in U251 cells

(2015) Zhongjian Liu et al.   TUMOR BIOLOGY

Cancer stem cells from epithelial ovarian cancer patients privilege oxidative phosphorylation, and resist glucose deprivation

(2015) Anna Pastò et al.   Oncotarget

Metabolic differences in breast cancer stem cells and differentiated progeny

(2014) Erina Vlashi et al.   BREAST CANCER RESEARCH AND TREATMENT

JNK contributes to temozolomide resistance of stem-like glioblastoma cells via regulation of MGMT expression

(2013) MASASHI OKADA et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Roles for MYC in the Establishment and Maintenance of Pluripotency

(2013) J. Chappell et al.   Cold Spring Harbor Perspectives in Medicine

Mitochondrial transcription factor A regulates mitochondrial transcription initiation, DNA packaging, and genome copy number

(2012) Christopher T. Campbell et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Imp2 controls oxidative phosphorylation and is crucial for preserving glioblastoma cancer stem cells

(2012) M. Janiszewska et al.   GENES & DEVELOPMENT

Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation

(2012) Kenta Kuramoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting JNK for therapeutic depletion of stem-like glioblastoma cells

(2012) Ken-ichiro Matsuda et al.   Scientific Reports

Glioma-Initiating Cell Elimination by Metformin Activation of FOXO3 via AMPK

(2012) Atsushi Sato et al.   Stem Cells Translational Medicine

Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ

(2011) Diana Whitaker-Menezes et al.   CELL CYCLE

Targeting the Mitochondria Activates Two Independent Cell Death Pathways in Ovarian Cancer Stem Cells

(2011) A. B. Alvero et al.   MOLECULAR CANCER THERAPEUTICS

Metabolic state of glioma stem cells and nontumorigenic cells

(2011) E. Vlashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TGF-β Receptor Inhibitors Target the CD44high/Id1high Glioma-Initiating Cell Population in Human Glioblastoma

(2010) Judit Anido et al.   CANCER CELL

Verteporfin-photoinduced apoptosis in HepG2 cells mediated by reactive oxygen and nitrogen species intermediates

(2010) Jeng-Fong Chiou et al.   FREE RADICAL RESEARCH

TGF-β Increases Glioma-Initiating Cell Self-Renewal through the Induction of LIF in Human Glioblastoma

(2009) Silvia Peñuelas et al.   CANCER CELL

Metformin Selectively Targets Cancer Stem Cells, and Acts Together with Chemotherapy to Block Tumor Growth and Prolong Remission

(2009) H. A. Hirsch et al.   CANCER RESEARCH

Intravital Microscopic Analysis of Vascular Perfusion and Macromolecule Extravasation after Photodynamic Vascular Targeting Therapy

(2008) Chong He et al.   PHARMACEUTICAL RESEARCH