Resident alveolar macrophage‐derived vesicular SOCS3 dampens allergic airway inflammation

Novel inhaled pan-JAK inhibitor, LAS194046, reduces allergen-induced airway inflammation, late asthmatic response and pSTATs activation in Brown Norway rats.

(2019) Marta Calbet et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Macrophage dysfunction in the pathogenesis and treatment of asthma

(2017) Michael Fricker et al.   EUROPEAN RESPIRATORY JOURNAL

Mechanisms and modulation of microvesicle uptake in a model of alveolar cell communication

(2017) Daniel J. Schneider et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative Regulation of Cytokine Signaling in Immunity

(2017) Akihiko Yoshimura et al.   Cold Spring Harbor Perspectives in Biology

Targeting the JAK-STAT pathway in the treatment of ‘Th2-high’ severe asthma

(2016) Kara Vale   Future Medicinal Chemistry

Alveolar Epithelial Cell–Derived Prostaglandin E2Serves as a Request Signal for Macrophage Secretion of Suppressor of Cytokine Signaling 3 during Innate Inflammation

(2016) Jennifer M. Speth et al.   JOURNAL OF IMMUNOLOGY

FoxO1 regulates allergic asthmatic inflammation through regulating polarization of the macrophage inflammatory phenotype

(2016) Sangwoon Chung et al.   Oncotarget

Recruited Alveolar Macrophages, in Response to Airway Epithelial–Derived Monocyte Chemoattractant Protein 1/CCL2, Regulate Airway Inflammation and Remodeling in Allergic Asthma

(2015) Yong Gyu Lee et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

SOCS3 Silencing Attenuates Eosinophil Functions in Asthma Patients

(2015) Mª Zafra et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling

(2015) Emilie Bourdonnay et al.   JOURNAL OF EXPERIMENTAL MEDICINE

AT-RvD1 Modulates CCL-2 and CXCL-8 Production and NF-κB, STAT-6, SOCS1, and SOCS3 Expression on Bronchial Epithelial Cells Stimulated with IL-4

(2015) Jhony Robison de Oliveira et al.   Biomed Research International

Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles

(2014) Marina Colombo et al.   Annual Review of Cell and Developmental Biology

Resident Alveolar Macrophages Suppress, whereas Recruited Monocytes Promote, Allergic Lung Inflammation in Murine Models of Asthma

(2014) Zbigniew Zasłona et al.   JOURNAL OF IMMUNOLOGY

Sessile alveolar macrophages communicate with alveolar epithelium to modulate immunity

(2014) Kristin Westphalen et al.   NATURE

Prostaglandin E2 suppresses allergic sensitization and lung inflammation by targeting the E prostanoid 2 receptor on T cells

(2013) Zbigniew Zasłona et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Janus kinase 1/3 signaling pathways are key initiators of TH2 differentiation and lung allergic responses

(2013) Shigeru Ashino et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Characterization of Macrophage Phenotypes in Three Murine Models of House-Dust-Mite-Induced Asthma

(2013) Christina Draijer et al.   MEDIATORS OF INFLAMMATION

The airway epithelium in asthma

(2012) Bart N Lambrecht et al.   NATURE MEDICINE

The sentinel role of the airway epithelium in asthma pathogenesis

(2011) Stephen T. Holgate   IMMUNOLOGICAL REVIEWS

Fluticasone propionate and Salmeterol combination induces SOCS-3 expression in airway epithelial cells

(2011) Najmunnisa Nasreen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Effects of a Janus kinase inhibitor, pyridone 6, on airway responses in a murine model of asthma

(2010) Yuko Matsunaga et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophages

(2009) Barbro N. Melgert et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Characterization of immortalized MARCO and SR-AI/II-deficient murine alveolar macrophage cell lines

(2008) Hongwei Zhou et al.   Particle and Fibre Toxicology