MiR‐144 protects the heart from hyperglycemia‐induced injury by regulating mitochondrial biogenesis and cardiomyocyte apoptosis

MiR-30c/PGC-1β protects against diabetic cardiomyopathy via PPARα

(2019) Zhongwei Yin et al.   Cardiovascular Diabetology

Hyperglycemia-Driven Inhibition of AMP-Activated Protein Kinase α2 Induces Diabetic Cardiomyopathy by Promoting Mitochondria-AssociatedEndoplasmic Reticulum Membranes in vivo

(2019) Shengnan Wu et al.   CIRCULATION

Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy

(2019) Mingming Tong et al.   CIRCULATION RESEARCH

Early dysregulation of cardiac-specific microRNA-208a is linked to maladaptive cardiac remodelling in diabetic myocardium

(2019) Shruti Rawal et al.   Cardiovascular Diabetology

Activation of Mitophagy in High-Fat Diet–Induced Diabetic Cardiomyopathy

(2019) Inna Rabinovich-Nikitin et al.   CIRCULATION RESEARCH

MiR-451 antagonist protects against cardiac fibrosis in streptozotocin-induced diabetic mouse heart

(2019) Cui Liang et al.   LIFE SCIENCES

Differential effect of glucose on ER-mitochondria Ca2+ exchange participates to insulin secretion and to glucotoxicity-mediated dysfunction of β cells.

(2019) Florian Dingreville et al.   DIABETES

Intensive Glucose Control in Patients with Type 2 Diabetes — 15-Year Follow-up

(2019) Peter D. Reaven et al.   NEW ENGLAND JOURNAL OF MEDICINE

Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation

(2018) I van der Pluijm et al.   CARDIOVASCULAR RESEARCH

Emerging Actors in Diabetic Cardiomyopathy: Heartbreaker Biomarkers or Therapeutic Targets?

(2018) Xavier Palomer et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Rac1 Modulates Endothelial Function and Platelet Aggregation in Diabetes Mellitus

(2018) Gabriele Giacomo Schiattarella et al.   Journal of the American Heart Association

Mitochondria-targeting drug conjugates for cytotoxic, anti-oxidizing and sensing purposes: current strategies and future perspectives

(2018) Gantumur Battogtokh et al.   Acta Pharmaceutica Sinica B

MiR-21 protected against diabetic cardiomyopathy induced diastolic dysfunction by targeting gelsolin

(2018) Beibei Dai et al.   Cardiovascular Diabetology

Of mice and men: models and mechanisms of diabetic cardiomyopathy

(2018) Christian Riehle et al.   BASIC RESEARCH IN CARDIOLOGY

MiR-133a Mimic Alleviates T1DM-Induced Systolic Dysfunction in Akita: An MRI-Based Study

(2018) Shyam Sundar Nandi et al.   Frontiers in Physiology

Recombinant human glucagon-like peptide-1 protects against chronic intermittent hypoxia by improving myocardial energy metabolism and mitochondrial biogenesis

(2018) Lichan Tao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate

(2017) Ning Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miR-146a mediates inflammatory changes and fibrosis in the heart in diabetes

(2017) Biao Feng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

SIRT1 Activation by Resveratrol Alleviates Cardiac Dysfunction via Mitochondrial Regulation in Diabetic Cardiomyopathy Mice

(2017) Sai Ma et al.   Oxidative Medicine and Cellular Longevity

Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway

(2017) Yuehong Wang et al.   Cell Death & Disease

Hsp20-Mediated Activation of Exosome Biogenesis in Cardiomyocytes Improves Cardiac Function and Angiogenesis in Diabetic Mice

(2016) Xiaohong Wang et al.   DIABETES

Mitochondrial biogenesis and clearance: a balancing act

(2016) Christina Ploumi et al.   FEBS Journal

Hyperglycemia-induced changes in miRNA expression patterns in epicardial adipose tissue of piglets

(2016) Ewa Ocłoń et al.   JOURNAL OF ENDOCRINOLOGY

Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging

(2016) Sherif F. Nagueh et al.   JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY

MicroRNA-200c modulates DUSP-1 expression in diabetes-induced cardiac hypertrophy

(2016) Gurinder Bir Singh et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

miR-30c and miR-181a synergistically modulate p53–p21 pathway in diabetes induced cardiac hypertrophy

(2016) Satish K. Raut et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Inhibiting microRNA-144 abates oxidative stress and reduces apoptosis in hearts of streptozotocin-induced diabetic mice

(2015) Manli Yu et al.   CARDIOVASCULAR PATHOLOGY

Mitochondrial biogenesis and dynamics in the developing and diseased heart

(2015) Gerald W. Dorn et al.   GENES & DEVELOPMENT

Kruppel-like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis

(2015) Xudong Liao et al.   JOURNAL OF CLINICAL INVESTIGATION

Noncoding RNAs as regulators of cardiomyocyte proliferation and death

(2015) Maria-Teresa Piccoli et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Doppler Echocardiographic Measurements in Normal Chinese Adults (EMINCA): a prospective, nationwide, and multicentre study

(2015) Gui-Hua Yao et al.   European Heart Journal-Cardiovascular Imaging

Rac-1 as a New Therapeutic Target in Cerebro- and Cardio-Vascular Diseases

(2014) Albino Carrizzo et al.   CURRENT DRUG TARGETS

Molecular mechanisms of diabetic cardiomyopathy

(2014) Heiko Bugger et al.   DIABETOLOGIA

MicroRNAs as Therapeutic Targets and Biomarkers of Cardiovascular Disease

(2014) E. N. Olson   Science Translational Medicine

After the banquet

(2013) Jianhui Zhu et al.   Autophagy

Impaired mitochondrial biogenesis due to dysfunctional adiponectin-AMPK-PGC-1α signaling contributing to increased vulnerability in diabetic heart

(2013) Wenjun Yan et al.   BASIC RESEARCH IN CARDIOLOGY

Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1

(2012) Xiaohong Wang et al.   CARDIOVASCULAR RESEARCH

MicroRNAs in Stress Signaling and Human Disease

(2012) Joshua T. Mendell et al.   CELL

Rac1 Is a Novel Regulator of Contraction-Stimulated Glucose Uptake in Skeletal Muscle

(2012) L. Sylow et al.   DIABETES

Diabetic cardiomyopathy and metabolic remodeling of the heart

(2012) Pavan K. Battiprolu et al.   LIFE SCIENCES

AMP-activated protein kinase enhances the phagocytic ability of macrophages and neutrophils

(2011) Hong-Beom Bae et al.   FASEB JOURNAL

Transient upregulation of PGC-1α diminishes cardiac ischemia tolerance via upregulation of ANT1

(2010) Edward G. Lynn et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

PGC-1α plays a functional role in exercise-induced mitochondrial biogenesis and angiogenesis but not fiber-type transformation in mouse skeletal muscle

(2009) Tuoyu Geng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Contribution of Impaired Myocardial Insulin Signaling to Mitochondrial Dysfunction and Oxidative Stress in the Heart

(2009) Sihem Boudina et al.   CIRCULATION

Rac1 Is Required for Cardiomyocyte Apoptosis During Hyperglycemia

(2009) E. Shen et al.   DIABETES

Regulation of Rac1 by Simvastatin in Endothelial Cells

(2009) Ruqin Kou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human Heart

(2009) Ethan J. Anderson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Transcriptional control of mitochondrial biogenesis: the central role of PGC-1 

(2008) R. Ventura-Clapier et al.   CARDIOVASCULAR RESEARCH

Retinoic Acid Leads to Cytoskeletal Rearrangement through AMPK-Rac1 and Stimulates Glucose Uptake through AMPK-p38 MAPK in Skeletal Muscle Cells

(2008) Yun Mi Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY