Hypoxia‐induced HE4 in tubular epithelial cells promotes extracellular matrix accumulation and renal fibrosis via NF‐κB

Human Epididymis Protein 4: A Novel Biomarker for Lupus Nephritis and Chronic Kidney Disease in Systemic Lupus Erythematosus

(2016) Zaixing Yang et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

A mechanistic link between renal ischemia and fibrosis

(2016) Tetsuhiro Tanaka   Medical Molecular Morphology

High glucose induces rat mesangial cells proliferation and MCP-1 expression via ROS-mediated activation of NF-κB pathway, which is inhibited by eleutheroside E

(2015) Xiuqin Yang et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Fibroblasts in fibrosis: novel roles and mediators

(2014) Ryan T. Kendall et al.   Frontiers in Pharmacology

Sesquiterpene Lactones and Their Derivatives Inhibit High Glucose-Induced NF-κB Activation and MCP-1 and TGF-β1 Expression in Rat Mesangial Cells

(2013) Qian-Qian Jia et al.   MOLECULES

Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis

(2013) Valerie S LeBleu et al.   NATURE MEDICINE

Molecular targets for treatment of kidney fibrosis

(2012) Peter Y. Chuang et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Extracellular Matrix and Fibroblast Communication Following Myocardial Infarction

(2012) Yonggang Ma et al.   Journal of Cardiovascular Translational Research

Hypoxia-inducible factor signaling in the development of tissue fibrosis

(2011) Debra F. Higgins et al.   CELL CYCLE

Comparison of Serum Human Epididymis Protein 4 with Cancer Antigen 125 as a Tumor Marker in Patients with Malignant and Nonmalignant Diseases

(2011) J. M. Escudero et al.   CLINICAL CHEMISTRY

Tissue inhibitor of metalloproteinases (TIMPs) in heart failure

(2011) Linn Moore et al.   HEART FAILURE REVIEWS

Overexpression of MMP-9 and HIF-1α in Breast Cancer Cells under Hypoxic Conditions

(2011) Jae Young Choi et al.   Journal of Breast Cancer

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Hypoxia-inducible factor-1α induces Twist expression in tubular epithelial cells subjected to hypoxia, leading to epithelial-to-mesenchymal transition

(2009) Shiren Sun et al.   KIDNEY INTERNATIONAL

Matrix metalloproteinases and matrix receptors in progression and reversal of kidney disease: therapeutic perspectives

(2008) Pierre Ronco et al.   KIDNEY INTERNATIONAL

Chronic hypoxia as a mechanism of progression of chronic kidney diseases: from hypothesis to novel therapeutics

(2008) Leon G. Fine et al.   KIDNEY INTERNATIONAL