Maternal regulation of SATB2 in osteo‐progeniters impairs skeletal development in offspring

Enhancer of zeste homolog 2 (Ezh2) controls bone formation and cell cycle progression during osteogenesis in mice

(2018) Amel Dudakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Maternal obesity impairs skeletal development in adult offspring

(2018) Jin-Ran Chen et al.   JOURNAL OF ENDOCRINOLOGY

Clinical and molecular consequences of disease-associated de novo mutations in SATB2

(2017) Hemant Bengani et al.   GENETICS IN MEDICINE

Maternal Macronutrient Consumption and the Developmental Origins of Metabolic Disease in the Offspring

(2017) Stephanie Kereliuk et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structure, mechanism, and regulation of polycomb repressive complex 2

(2017) Lindsay E. Moritz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma–Induced Epigenetic Suppression of Osteoblast Differentiation

(2017) Juraj Adamik et al.   MOLECULAR CANCER RESEARCH

Maternal Obesity Programs Senescence Signaling and Glucose Metabolism in Osteo-Progenitors From Rat and Human

(2016) Jin-Ran Chen et al.   ENDOCRINOLOGY

Enhancer of Zeste Homolog 2 Inhibition Stimulates Bone Formation and Mitigates Bone Loss Caused by Ovariectomy in Skeletally Mature Mice

(2016) Amel Dudakovic et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of EZH2 Prevents the Shift of Osteoporotic MSC Fate to Adipocyte and Enhances Bone Formation During Osteoporosis

(2016) Huan Jing et al.   MOLECULAR THERAPY

What determines the switch between atrophic and neovascular forms ofage related macular degeneration? - the role of BMP4 induced senescence

(2016) DanHong Zhu et al.   Aging-US

Soy Protein Isolate Inhibits High-Fat Diet-Induced Senescence Pathways in Osteoblasts to Maintain Bone Acquisition in Male Rats

(2015) Jin-Ran Chen et al.   ENDOCRINOLOGY

Transcriptomic and epigenomic landscapes during cell fusion in BeWo trophoblast cells

(2015) Kartik Shankar et al.   PLACENTA

The Interaction between Epigenetics, Nutrition and the Development of Cancer

(2015) Karen Bishop et al.   Nutrients

Maternal Dietary Patterns during Pregnancy in Relation to Offspring Forearm Fractures: Prospective Study from the Danish National Birth Cohort

(2015) Sesilje Petersen et al.   Nutrients

Distinct adipogenic differentiation phenotypes of human umbilical cord mesenchymal cells dependent on adipogenic conditions

(2014) Jessica Saben et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Programming of Osteoporosis and Impact on Osteoporosis Risk

(2013) ELAINE M. DENNISON et al.   CLINICAL OBSTETRICS AND GYNECOLOGY

Maternal Obesity Induces Epigenetic Modifications to Facilitate Zfp423 Expression and Enhance Adipogenic Differentiation in Fetal Mice

(2013) Q.-Y. Yang et al.   DIABETES

Soy protein isolates prevent loss of bone quantity associated with obesity in rats through regulation of insulin signaling in osteoblasts

(2013) Jin-Ran Chen et al.   FASEB JOURNAL

EZH2andKDM6AAct as an Epigenetic Switch to Regulate Mesenchymal Stem Cell Lineage Specification

(2013) Sarah Hemming et al.   STEM CELLS

The Insulin-Like Growth Factor System in Bone

(2012) Masanobu Kawai et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs

(2012) Jiekai Chen et al.   NATURE GENETICS

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

Inhibition of fetal bone development through epigenetic down-regulation of HoxA10 in obese rats fed high-fat diet

(2011) Jin-Ran Chen et al.   FASEB JOURNAL

Osteoblast-specific Transcription Factor Osterix (Osx) Is an Upstream Regulator of Satb2 during Bone Formation

(2011) Wanjin Tang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation

(2011) Jason Gertz et al.   PLoS Genetics

Epigenetics of programmed obesity: alteration in IUGR rat hepatic IGF1 mRNA expression and histone structure in rapid vs. delayed postnatal catch-up growth

(2010) Darran N. Tosh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells

(2010) Yongkun Wei et al.   NATURE CELL BIOLOGY

Obesity Reduces Bone Density Associated with Activation of PPARγ and Suppression of Wnt/β-Catenin in Rapidly Growing Male Rats

(2010) Jin-Ran Chen et al.   PLoS One

Histone H3K27 methyltransferase Ezh2 represses Wnt genes to facilitate adipogenesis

(2010) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gestational high saturated fat diet alters C57BL/6 mouse perinatal skeletal formation

(2009) Chengya Liang et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

SATB2 interacts with chromatin-remodeling molecules in differentiating cortical neurons

(2008) Andrea B. Gyorgy et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Maternal obesity at conception programs obesity in the offspring

(2007) Kartik Shankar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Diet-Induced Obesity in Female Mice Leads to Offspring Hyperphagia, Adiposity, Hypertension, and Insulin Resistance

(2007) Anne-Maj Samuelsson et al.   HYPERTENSION