The GR-ANXA1 pathway is a pathological player and a candidate target in epilepsy

Annexin A1-derived peptide Ac2-26 in a pilocarpine-induced status epilepticus model: anti-inflammatory and neuroprotective effects

(2019) Alexandre D. Gimenes et al.   Journal of Neuroinflammation

Functional deficiency in endogenous interleukin-1 receptor antagonist in patients with febrile infection-related epilepsy syndrome

(2019) Benjamin D. S. Clarkson et al.   ANNALS OF NEUROLOGY

A pericyte‐glia scarring develops at the leaky capillaries in the hippocampus during seizure activity

(2019) Wendy Klement et al.   EPILEPSIA

Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy

(2019) Annamaria Vezzani et al.   Nature Reviews Neurology

Annexin-A1: Therapeutic Potential in Microvascular Disease

(2019) Gareth S. D. Purvis et al.   Frontiers in Immunology

Peripherally derived T regulatory and γδ T cells have opposing roles in the pathogenesis of intractable pediatric epilepsy

(2018) Dan Xu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Systemic autoinflammation with intractable epilepsy managed with interleukin-1 blockade

(2018) Allen D. DeSena et al.   Journal of Neuroinflammation

Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature

(2018) Wendy Klement et al.   NEUROBIOLOGY OF DISEASE

Hepatic and hippocampal cytochrome P450 enzyme overexpression during spontaneous recurrent seizures

(2017) Leonie Runtz et al.   EPILEPSIA

Identification of two phosphorylation sites essential for annexin A1 in blood–brain barrier protection after experimental intracerebral hemorrhage in rats

(2016) Zhong Wang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Resolution of inflammation: a new therapeutic frontier

(2016) James N. Fullerton et al.   NATURE REVIEWS DRUG DISCOVERY

New selective glucocorticoid receptor modulators reverse amyloid-β peptide–induced hippocampus toxicity

(2016) Fanny Pineau et al.   NEUROBIOLOGY OF AGING

Infiltrating monocytes promote brain inflammation and exacerbate neuronal damage after status epilepticus

(2016) Nicholas H. Varvel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Annexin A1 and the Resolution of Inflammation: Modulation of Neutrophil Recruitment, Apoptosis, and Clearance

(2016) Michelle Amantéa Sugimoto et al.   Journal of Immunology Research

Annexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice

(2015) P G Trentin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effectiveness of a hybrid corticosteroid treatment regimen on refractory childhood seizures and a review of other corticosteroid treatments

(2015) Dewi P. Bakker et al.   EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY

Resolution Pharmacology: Opportunities for Therapeutic Innovation in Inflammation

(2015) Mauro Perretti et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet

(2015) Dennis H. M. Kusters et al.   PLoS One

Losartan prevents acquired epilepsy via TGF-β signaling suppression

(2014) Guy Bar-Klein et al.   ANNALS OF NEUROLOGY

Annexin A1: potential for glucocorticoid sparing in RA

(2013) Yuan H. Yang et al.   Nature Reviews Rheumatology

Annexin Peptide Ac2-26 Suppresses TNFα-Induced Inflammatory Responses via Inhibition of Rac1-Dependent NADPH Oxidase in Human Endothelial Cells

(2013) Hitesh M. Peshavariya et al.   PLoS One

Identification of an essential endogenous regulator of blood-brain barrier integrity, and its pathological and therapeutic implications

(2013) E. Cristante et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory pathways of seizure disorders

(2013) Nicola Marchi et al.   TRENDS IN NEUROSCIENCES

Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation

(2012) Erwin A. van Vliet et al.   EPILEPSIA

Efficacy of Anti-Inflammatory Therapy in a Model of Acute Seizures and in a Population of Pediatric Drug Resistant Epileptics

(2011) Nicola Marchi et al.   PLoS One

The role of inflammation in epilepsy

(2010) Annamaria Vezzani et al.   Nature Reviews Neurology

Annexin-1 Regulates Macrophage IL-6 and TNF via Glucocorticoid-Induced Leucine Zipper

(2009) Y. H. Yang et al.   JOURNAL OF IMMUNOLOGY

The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders

(2009) Elisabeth B. Binder   PSYCHONEUROENDOCRINOLOGY