Targeting tumor interstitial fluid pressure: will it yield novel successful therapies for solid tumors?

The beginning of the end for conventional RECIST — novel therapies require novel imaging approaches

(2019) Mirjam Gerwing et al.   Nature Reviews Clinical Oncology

Mechanosensitive ion channels push cancer progression

(2019) Zoltán Pethő et al.   CELL CALCIUM

Tumor Vasculatures: A New Target for Cancer Immunotherapy

(2019) Zhigang Liu et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Tumor Heterogeneity Underlies Differential Cisplatin Sensitivity in Mouse Models of Small-Cell Lung Cancer

(2019) Franziska Böttger et al.   Cell Reports

Targeting the invincible barrier for drug delivery in solid cancers: interstitial fluid pressure

(2018) Steven K. Libutti et al.   Oncotarget

An Implantable Wireless Interstitial Pressure Sensor With Integrated Guyton Chamber: in vivo Study in Solid Tumors

(2016) Seung Hyun Song et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Spatial Measurements of Perfusion, Interstitial Fluid Pressure and Liposomes Accumulation in Solid Tumors

(2016) Shawn Stapleton et al.   Jove-Journal of Visualized Experiments

Interstitial Fluid Pressure Correlates Clinicopathological Factors of Lung Cancer

(2015) Takeshi Mori et al.   Annals of Thoracic and Cardiovascular Surgery

A pilot study of the effects of mild systemic heating on human head and neck tumour xenografts: Analysis of tumour perfusion, interstitial fluid pressure, hypoxia and efficacy of radiation therapy

(2015) Timothy B. Winslow et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Pseudoprogression and Immune-Related Response in Solid Tumors

(2015) Victoria L. Chiou et al.   JOURNAL OF CLINICAL ONCOLOGY

Associations of chemo- and radio-resistant phenotypes with the gap junction, adhesion and extracellular matrix in a three-dimensional culture model of soft sarcoma

(2015) Chujie Bai et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Drug sensitivity in cancer cell lines is not tissue-specific

(2015) Samira Jaeger et al.   Molecular Cancer

Tumor Interstitial Fluid Pressure as an Early-Response Marker for Anticancer Therapeutics

(2015) Stephane Ferretti et al.   NEOPLASIA

Vascular Endothelial Growth Factor Signaling in Hypoxia and Inflammation

(2014) S. Ramakrishnan et al.   Journal of Neuroimmune Pharmacology

Tumor Interstitial Fluid Pressure—A Link between Tumor Hypoxia, Microvascular Density, and Lymph Node Metastasis

(2014) Einar K. Rofstad et al.   NEOPLASIA

Bevacizumab-Induced Normalization of Blood Vessels in Tumors Hampers Antibody Uptake

(2013) M. Arjaans et al.   CANCER RESEARCH

Benefits of Vascular Normalization Are Dose and Time Dependent--Letter

(2013) Y. Huang et al.   CANCER RESEARCH

High interstitial fluid pressure promotes tumor progression through inducing lymphatic metastasis-related protein expressions in oral squamous cell carcinoma

(2013) T. Yu et al.   Clinical & Translational Oncology

High tumor interstitial fluid pressure identifies cervical cancer patients with improved survival from radiotherapy plus cisplatin versus radiotherapy alone

(2013) Michael F. Milosevic et al.   INTERNATIONAL JOURNAL OF CANCER

VEGFA and tumour angiogenesis

(2013) L. Claesson-Welsh et al.   JOURNAL OF INTERNAL MEDICINE

Epithelial-mesenchymal transition: focus on metastatic cascade, alternative splicing, non-coding RNAs and modulating compounds

(2013) Timur R Samatov et al.   Molecular Cancer

Vascular Hyperpermeability, Angiogenesis, and Stroma Generation

(2013) J. A. Nagy et al.   Cold Spring Harbor Perspectives in Medicine

Is it time for a new paradigm for systemic cancer treatment? Lessons from a century of cancer chemotherapy

(2013) Sarah Crawford   Frontiers in Pharmacology

Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases

(2012) M. Shibuya   JOURNAL OF BIOCHEMISTRY

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Are Metastases from Metastases Clinical Relevant? Computer Modelling of Cancer Spread in a Case of Hepatocellular Carcinoma

(2012) Anja Bethge et al.   PLoS One

High Interstitial Fluid Pressure Is Associated with Low Tumour Penetration of Diagnostic Monoclonal Antibodies Applied for Molecular Imaging Purposes

(2012) Markus Heine et al.   PLoS One

Role of tumor vascular architecture in drug delivery

(2011) Ajit S. Narang et al.   ADVANCED DRUG DELIVERY REVIEWS

Trastuzumab has anti-metastatic and anti-angiogenic activity in a spontaneous metastasis xenograft model of esophageal adenocarcinoma

(2011) Tobias Lange et al.   CANCER LETTERS

Investigations on the Usefulness of CEACAMs as Potential Imaging Targets for Molecular Imaging Purposes

(2011) Markus Heine et al.   PLoS One

Vascular endothelial growth factors and vascular permeability

(2010) D. O. Bates   CARDIOVASCULAR RESEARCH

Microvascular fluid exchange and the revised Starling principle

(2010) J. Rodney Levick et al.   CARDIOVASCULAR RESEARCH

Interstitial fluid pressure in tumors: therapeutic barrier and biomarker of angiogenesis

(2008) Sarah Jane Lunt et al.   Future Oncology

Measuring interstitial fluid pressure with fiberoptic pressure transducers

(2008) Ugur Ozerdem   MICROVASCULAR RESEARCH