PCAF ‐mediated acetylation of ISX recruits BRD 4 to promote epithelial‐mesenchymal transition

Risk factors for bone metastasis in patients with primary lung cancer

(2019) Yujie Niu et al.   MEDICINE

EMT is associated with an epigenetic signature of ECM remodeling genes

(2019) Paul Peixoto et al.   Cell Death & Disease

Open Chromatin, Epigenetic Plasticity, and Nuclear Organization in Pluripotency

(2019) Sharon Schlesinger et al.   DEVELOPMENTAL CELL

Inhibition of BRD4 suppresses the malignancy of breast cancer cells via regulation of Snail

(2019) Linlin Lu et al.   CELL DEATH AND DIFFERENTIATION

Exosome‐transmitted p120‐catenin suppresses hepatocellular carcinoma progression via STAT3 pathways

(2019) Zhangjun Cheng et al.   MOLECULAR CARCINOGENESIS

Chronic Obstructive Pulmonary Disease in Lung Cancer Patients: Prevalence, Underdiagnosis, and Clinical Characterization

(2018) Cecilia Mouronte-Roibás et al.   RESPIRATION

Histone Lysine and Genomic Targets of Histone Acetyltransferases in Mammals

(2018) Anne K. Voss et al.   BIOESSAYS

TIP60-dependent acetylation of the SPZ1-TWIST complex promotes epithelial–mesenchymal transition and metastasis in liver cancer

(2018) Li-Ting Wang et al.   ONCOGENE

Targeting Brd4 for cancer therapy: inhibitors and degraders

(2018) Yingchao Duan et al.   MedChemComm

BRD4 and Cancer: going beyond transcriptional regulation

(2018) Benedetta Donati et al.   Molecular Cancer

Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC

(2016) Shen-Nien Wang et al.   Oncotarget

BRD4 Phosphorylation Regulates HPV E2-Mediated Viral Transcription, Origin Replication, and Cellular MMP-9 Expression

(2016) Shwu-Yuan Wu et al.   Cell Reports

PCAF-primed EZH2 acetylation regulates its stability and promotes lung adenocarcinoma progression

(2015) Junhu Wan et al.   NUCLEIC ACIDS RESEARCH

The Mechanisms behind the Therapeutic Activity of BET Bromodomain Inhibition

(2014) Junwei Shi et al.   MOLECULAR CELL

EMT Twists the Road to PI3K

(2014) M. J. Niederst et al.   Cancer Discovery

PCAF ubiquitin ligase activity inhibits Hedgehog/Gli1 signaling in p53-dependent response to genotoxic stress

(2013) D Mazzà et al.   CELL DEATH AND DIFFERENTIATION

Vimentin expression predicts the occurrence of metastases in non small cell lung carcinomas

(2013) Maryline Dauphin et al.   LUNG CANCER

Phospho Switch Triggers Brd4 Chromatin Binding and Activator Recruitment for Gene-Specific Targeting

(2013) Shwu-Yuan Wu et al.   MOLECULAR CELL

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

Defining and searching for structural motifs using DeepView/Swiss-PdbViewer

(2012) Maria U Johansson et al.   BMC BIOINFORMATICS

Proinflammatory Homeobox Gene, ISX, Regulates Tumor Growth and Survival in Hepatocellular Carcinoma

(2012) S.-H. Hsu et al.   CANCER RESEARCH

The p53-HAT connection: PCAF rules?

(2012) Oleg Laptenko et al.   CELL CYCLE

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Twist1-Induced Invadopodia Formation Promotes Tumor Metastasis

(2011) Mark A. Eckert et al.   CANCER CELL

ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading

(2010) Paul Mak et al.   CANCER CELL

Ubiquitin carboxyl-terminal hydrolase L1 (UCHL1) regulates the level of SMN expression through ubiquitination in primary spinal muscular atrophy fibroblasts

(2010) Shih-Hsien Hsu et al.   CLINICA CHIMICA ACTA

Tumorigenesis: Twist1 links EMT to self-renewal

(2010) Alberto Martin et al.   NATURE CELL BIOLOGY

Cancer Metastasis Is Accelerated through Immunosuppression during Snail-Induced EMT of Cancer Cells

(2009) Chie Kudo-Saito et al.   CANCER CELL

The Transcriptional Repressor ZEB1 Promotes Metastasis and Loss of Cell Polarity in Cancer

(2008) S. Spaderna et al.   CANCER RESEARCH