Maintaining protein stability of ∆Np63 via USP 28 is required by squamous cancer cells

LUBAC determines chemotherapy resistance in squamous cell lung cancer

(2019) E. Josue Ruiz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Protocol Update for large-scale genome and gene function analysis with the PANTHER classification system (v.14.0)

(2019) Huaiyu Mi et al.   Nature Protocols

Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities

(2019) Florian Sauer et al.   MOLECULAR CELL

Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity

(2019) Malte Gersch et al.   MOLECULAR CELL

OTULIN deficiency in ORAS causes cell type‐specific LUBAC degradation, dysregulated TNF signalling and cell death

(2019) Rune Busk Damgaard et al.   EMBO Molecular Medicine

ΔNp63α modulates phosphorylation of p38 MAP kinase in regulation of cell cycle progression and cell growth

(2019) Liang Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeting Transcription Factors for Cancer Treatment

(2018) Mélanie Lambert et al.   MOLECULES

Targeting deubiquitinase USP28 for cancer therapy

(2018) Xiaofang Wang et al.   Cell Death & Disease

Validation of miRNA prognostic power in hepatocellular carcinoma using expression data of independent datasets

(2018) Ádám Nagy et al.   Scientific Reports

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas

(2018) Christopher G. Abraham et al.   Cell Reports

Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?

(2018) Venus Sosa Iglesias et al.   Frontiers in Oncology

DeltaNp63-dependent super enhancers define molecular identity in pancreatic cancer by an interconnected transcription factor network

(2018) Feda H. Hamdan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma

(2018) Tim D.D. Somerville et al.   Cell Reports

Prediction of potent shRNAs with a sequential classification algorithm

(2017) Raphael Pelossof et al.   NATURE BIOTECHNOLOGY

GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses

(2017) Zefang Tang et al.   NUCLEIC ACIDS RESEARCH

Active site-targeted covalent irreversible inhibitors of USP7 impair the functions of Foxp3+ T-regulatory cells by promoting ubiquitination of Tip60

(2017) Feng Wang et al.   PLoS One

Multiplexed in vivo homology-directed repair and tumor barcoding enables parallel quantification of Kras variant oncogenicity

(2017) Ian P. Winters et al.   Nature Communications

Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle

(2017) Gabriele Büchel et al.   Cell Reports

Lung Cancer: Understanding Its Molecular Pathology and the 2015 WHO Classification

(2017) Kentaro Inamura   Frontiers in Oncology

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin

(2016) Giustina Ferone et al.   CANCER CELL

The recognition of ubiquitinated proteins by the proteasome

(2016) Guinevere L. Grice et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A USP28–53BP1–p53–p21 signaling axis arrests growth after centrosome loss or prolonged mitosis

(2016) Bramwell G. Lambrus et al.   JOURNAL OF CELL BIOLOGY

53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration

(2016) Franz Meitinger et al.   JOURNAL OF CELL BIOLOGY

Oncogenic mutations in the FBXW7 gene of adult T-cell leukemia patients

(2016) Chien-Hung Yeh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance

(2016) Catherine A. Cremona et al.   SEMINARS IN CANCER BIOLOGY

53BP1 and USP28 mediate p53-dependent cell cycle arrest in response to centrosome loss and prolonged mitosis

(2016) Chii Shyang Fong et al.   eLife

Targeting the ubiquitin pathway for cancer treatment

(2015) Jia Liu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Usp28 Counteracts Fbw7 in Intestinal Homeostasis and Cancer

(2015) M. E. Diefenbacher et al.   CANCER RESEARCH

Quantitative Analysis of Histological Staining and Fluorescence Using ImageJ

(2014) Ellen C. Jensen   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Targeting molecular addictions in cancer

(2014) I Vivanco   BRITISH JOURNAL OF CANCER

Loss of Lkb1 and Pten Leads to Lung Squamous Cell Carcinoma with Elevated PD-L1 Expression

(2014) Chunxiao Xu et al.   CANCER CELL

The cell of origin and subtype of K-Ras-induced lung tumors are modified by Notch and Sox2

(2014) Xia Xu et al.   GENES & DEVELOPMENT

The deubiquitinase USP28 controls intestinal homeostasis and promotes colorectal cancer

(2014) Markus E. Diefenbacher et al.   JOURNAL OF CLINICAL INVESTIGATION

Sox2 Cooperates with Lkb1 Loss in a Mouse Model of Squamous Cell Lung Cancer

(2014) Anandaroop Mukhopadhyay et al.   Cell Reports

Dual Regulation of Fbw7 Function and Oncogenic Transformation by Usp28

(2014) Christina Schülein-Völk et al.   Cell Reports

FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

(2013) Matthew R. Ramsey et al.   JOURNAL OF CLINICAL INVESTIGATION

OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling

(2013) Berthe Katrine Fiil et al.   MOLECULAR CELL

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

p63 regulates cell proliferation and cell cycle progression-associated genes in stromal cells of giant cell tumor of the bone

(2012) CAROL PO YING LAU et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Quantification of AAV Particle Titers by Infrared Fluorescence Scanning of Coomassie-Stained Sodium Dodecyl Sulfate–Polyacrylamide Gels

(2012) Erik Kohlbrenner et al.   Human Gene Therapy Methods

Ubiquitination of E3 ligases: self-regulation of the ubiquitin system via proteolytic and non-proteolytic mechanisms

(2011) P de Bie et al.   CELL DEATH AND DIFFERENTIATION

p63 maintains keratinocyte proliferative capacity through regulation of Skp2-p130 levels

(2011) S. S. McDade et al.   JOURNAL OF CELL SCIENCE

The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages

(2010) Angelo Peschiaroli et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lung Squamous Cell Carcinoma mRNA Expression Subtypes Are Reproducible, Clinically Important, and Correspond to Normal Cell Types

(2010) M. D. Wilkerson et al.   CLINICAL CANCER RESEARCH

MDM2 and Fbw7 cooperate to induce p63 protein degradation following DNA damage and cell differentiation

(2010) F. Galli et al.   JOURNAL OF CELL SCIENCE

ΔNp63 transcriptionally regulates ATM to control p53 Serine-15 phosphorylation

(2010) Ashley L Craig et al.   Molecular Cancer

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Efficient protection and isolation of ubiquitylated proteins using tandem ubiquitin-binding entities

(2009) Roland Hjerpe et al.   EMBO REPORTS