The Sphkl/SlP pathway regulates angiogenesis via NOS/NO synthesis following cerebral ischemia‐reperfusion

Role of Perivascular Oligodendrocyte Precursor Cells in Angiogenesis After Brain Ischemia

(2019) Natsue Kishida et al.   Journal of the American Heart Association

Protective Effects of Curcumin Against Ischemia-Reperfusion Injury in the Nervous System

(2018) Kowsar Bavarsad et al.   MOLECULAR NEUROBIOLOGY

Sphk1 mediates neuroinflammation and neuronal injury via TRAF2/NF-κB pathways in activated microglia in cerebral ischemia reperfusion

(2017) Danying Su et al.   JOURNAL OF NEUROIMMUNOLOGY

Vascular expression of angiopoietin1, α5β1 integrin and tight junction proteins is tightly regulated during vascular remodeling in the post-ischemic brain

(2017) Jialan Sun et al.   NEUROSCIENCE

Sphingosine kinase 1/sphingosine-1-phosphate regulates the expression of interleukin-17A in activated microglia in cerebral ischemia/reperfusion

(2016) Manhua Lv et al.   INFLAMMATION RESEARCH

SIRT1 mediates Sphk1/S1P-induced proliferation and migration of endothelial cells

(2016) Zhan Gao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Simvastatin Reduces Lipopolysaccharides-Accelerated Cerebral Ischemic Injury via Inhibition of Nuclear Factor-kappa B Activity

(2015) Angela M. A. Anthony Jalin et al.   Biomolecules & Therapeutics

Coupling of neurogenesis and angiogenesis after ischemic stroke

(2015) Linhui Ruan et al.   BRAIN RESEARCH

The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling

(2015) Graeme M. Birdsey et al.   DEVELOPMENTAL CELL

Selective modulation of microglia polarization to M2 phenotype for stroke treatment

(2015) Cong-Yuan Xia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Remodeling of Cerebral Microcirculation after Ischemia-Reperfusion

(2015) Dominga Lapi et al.   JOURNAL OF VASCULAR RESEARCH

Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke

(2015) Gab Seok Kim et al.   Nature Communications

G-Protein-Coupled Receptor Cell Signaling Pathways Mediating Embryonic Chick Retinal Growth Cone Collapse Induced by Lysophosphatidic Acid and Sphingosine-1-Phosphate

(2014) Jarod Fincher et al.   DEVELOPMENTAL NEUROSCIENCE

The activation of RhoC in vascular endothelial cells is required for the S1P receptor type 2-induced inhibition of angiogenesis

(2013) Sabrina Del Galdo et al.   CELLULAR SIGNALLING

Sphingosine 1-phosphate signalling

(2013) K. Mendelson et al.   DEVELOPMENT

Sphingosine-1-phosphate protects against bisphosphonate-induced HUVEC cell death via regulation of c-Jun-N-terminal kinase signaling

(2013) YOU-JIN LEE et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Fenretinide Causes Emphysema, Which Is Prevented by Sphingosine 1-Phoshate

(2013) Masanori Yasuo et al.   PLoS One

Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: Review of sphingosine kinase inhibitors

(2012) K. Alexa Orr Gandy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

The functional roles of S1P in immunity

(2012) Y. Hisano et al.   JOURNAL OF BIOCHEMISTRY

ETS-related Gene (ERG) Controls Endothelial Cell Permeability via Transcriptional Regulation of the Claudin 5 (CLDN5) Gene

(2012) Lei Yuan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Angiogenesis induced by CNS inflammation promotes neuronal remodeling through vessel-derived prostacyclin

(2012) Rieko Muramatsu et al.   NATURE MEDICINE

The transcription factor Erg regulates expression of histone deacetylase 6 and multiple pathways involved in endothelial cell migration and angiogenesis

(2011) G. M. Birdsey et al.   BLOOD

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Treatment of Acute Ischemic Stroke: Beyond Thrombolysis and Supportive Care

(2011) Neelofer Shafi et al.   Neurotherapeutics

Medical Therapy for Ischemic Stroke: Review of Intravenous and Intra-Arterial Treatment Options

(2011) Philipp Taussky et al.   World Neurosurgery

Roles of inflammation response in microglia cell through Toll-like receptors 2/interleukin-23/interleukin-17 pathway in cerebral ischemia/reperfusion injury

(2010) M. Lv et al.   NEUROSCIENCE

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

(2009) C. L. Allen et al.   International Journal of Stroke

Remapping of the somatosensory cortex after a photothrombotic stroke: dynamics of the compensatory reorganization

(2009) J.A. Jablonka et al.   NEUROSCIENCE

Sphingosine kinase 1 regulates the expression of proinflammatory cytokines and nitric oxide in activated microglia

(2009) D. Nayak et al.   NEUROSCIENCE

Sphingosine-1-Phosphate and Its Analogue FTY720 Diminish Acute Pulmonary Injury in Rats With Acute Necrotizing Pancreatitis

(2009) Hong-Bin Liu et al.   PANCREAS

Cerebral Blood Flow Regulation by Nitric Oxide: Recent Advances

(2009) N. Toda et al.   PHARMACOLOGICAL REVIEWS

Overlapping and distinct roles for PI3Kβ and γ isoforms in S1P-induced migration of human and mouse endothelial cells

(2008) Regine Heller et al.   CARDIOVASCULAR RESEARCH

Activation of Sphingosine Kinase-1 Reverses the Increase in Lung Vascular Permeability Through Sphingosine-1-Phosphate Receptor Signaling in Endothelial Cells

(2008) Mohammad Tauseef et al.   CIRCULATION RESEARCH