Protein Biomarker Quantification by Immunoaffinity Liquid Chromatography–Tandem Mass Spectrometry: Current State and Future Vision

Measuring the Turnover Rate of Clinically Important Plasma Proteins using an Automated SISCAPA Workflow

(2019) Morteza Razavi et al.   CLINICAL CHEMISTRY

Diagnosis of Hemoglobinopathy and β-Thalassemia by 21-Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Tandem Mass Spectrometry of Hemoglobin from Blood

(2019) Lidong He et al.   CLINICAL CHEMISTRY

Critical reagent screening and characterization: benefits and approaches for protein biomarker assays by hybrid LC–MS

(2019) Rasa Santockyte et al.   Bioanalysis

Human FcRn Tissue Expression Profile and Half-Life in PBMCs

(2019) Yao-Yun Fan et al.   Biomolecules

Improved LC-MS/MS method for the quantification of hepcidin-25 in clinical samples

(2018) Ioana M. Abbas et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Slow Off-Rate Modified Aptamer (SOMAmer) as a Novel Reagent in Immunoassay Development for Accurate Soluble Glypican-3 Quantification in Clinical Samples

(2018) Jia Duo et al.   ANALYTICAL CHEMISTRY

Liquid Chromatography-High Resolution Mass Spectrometry Analysis of Platelet Frataxin as a Protein Biomarker for the Rare Disease Friedreich’s Ataxia

(2018) Lili Guo et al.   ANALYTICAL CHEMISTRY

Multiplex Immuno-MALDI-TOF MS for Targeted Quantification of Protein Biomarkers and Their Proteoforms Related to Inflammation and Renal Dysfunction

(2018) Jie Gao et al.   ANALYTICAL CHEMISTRY

Quantification of Serum High Mobility Group Box 1 by Liquid Chromatography/High-Resolution Mass Spectrometry: Implications for Its Role in Immunity, Inflammation, and Cancer

(2018) Liwei Weng et al.   ANALYTICAL CHEMISTRY

Comprehensive Single-Shot Proteomics with FAIMS on a Hybrid Orbitrap Mass Spectrometer

(2018) Alexander S. Hebert et al.   ANALYTICAL CHEMISTRY

Assessment of Plasma Proteomics Biomarker’s Ability to Distinguish Benign From Malignant Lung Nodules

(2018) Gerard A. Silvestri et al.   CHEST

Resolution of Spurious Immunonephelometric IgG Subclass Measurement Discrepancies by LC-MS/MS

(2018) Grace van der Gugten et al.   CLINICAL CHEMISTRY

Measurement of Lipoprotein-Associated Phospholipase A2 by Use of 3 Different Methods: Exploration of Discordance between ELISA and Activity Assays

(2018) Celalettin Topbas et al.   CLINICAL CHEMISTRY

Direct Quantification of Cytochromes P450 and Drug Transporters—A Rapid, Targeted Mass Spectrometry-Based Immunoassay Panel for Tissues and Cell Culture Lysates

(2018) Frederik Weiß et al.   DRUG METABOLISM AND DISPOSITION

Nano-flow vs standard-flow: Which is the more suitable LC/MS method for quantifying hepcidin-25 in human serum in routine clinical settings?

(2018) Jérôme Vialaret et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Translational Pharmacokinetic/Pharmacodynamic Characterization and Target-Mediated Drug Disposition Modeling of an Anti–Tissue Factor Pathway Inhibitor Antibody, PF-06741086

(2018) Chuenlei Parng et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Rapid Affinity Enrichment of Human Apolipoprotein A-I Associated Lipoproteins for Proteome Analysis

(2018) Timothy S. Collier et al.   JOURNAL OF PROTEOME RESEARCH

Top-down mass spectrometric immunoassay for human insulin and its therapeutic analogs

(2018) Dobrin Nedelkov et al.   Journal of Proteomics

A novel differential ion mobility device expands the depth of proteome coverage and the sensitivity of multiplex proteomic measurements

(2018) Sibylle Pfammatter et al.   MOLECULAR & CELLULAR PROTEOMICS

Highly selective and sensitive measurement of active forms of FGF21 using novel immunocapture enrichment with LC–MS/MS

(2018) Yue Zhao et al.   Bioanalysis

Assessing the Feasibility of Neutralizing Osteopontin with Various Therapeutic Antibody Modalities

(2018) Vahid Farrokhi et al.   Scientific Reports

Development of a 25-Hydroxyvitamin D Liquid Chromatography–Tandem Mass Spectrometry Assay, Cleared by the Food and Drug Administration, via the De Novo Pathway

(2018) Nicole V. Tolan   CLINICS IN LABORATORY MEDICINE

Development and Validation of Apolipoprotein AI-Associated Lipoprotein Proteome Panel for the Prediction of Cholesterol Efflux Capacity and Coronary Artery Disease

(2018) Zhicheng Jin et al.   CLINICAL CHEMISTRY

Understanding extracellular vesicle diversity – current status

(2018) David W. Greening et al.   Expert Review of Proteomics

Online Parallel Accumulation–Serial Fragmentation (PASEF) with a Novel Trapped Ion Mobility Mass Spectrometer

(2018) Florian Meier et al.   MOLECULAR & CELLULAR PROTEOMICS

To elute or not to elute in immunocapture bottom-up LC–MS

(2017) Maren Christin Stillesby Levernæs et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Plasma PCSK9 measurement by liquid chromatography–Tandem mass spectrometry and comparison with conventional ELISA

(2017) Mikaël Croyal et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Anti-MAdCAM Antibody Increases ß7+ T Cells and CCR9 Gene Expression in the Peripheral Blood of Patients With Crohn’s Disease

(2017) Mina Hassan-Zahraee et al.   Journal of Crohns & Colitis

On-column trypsin digestion coupled with LC-MS/MS for quantification of apolipoproteins

(2017) Christopher A Toth et al.   Journal of Proteomics

Biomeasures and mechanistic modeling highlight PK/PD risks for a monoclonal antibody targeting Fn14 in kidney disease

(2017) Xiaoying Chen et al.   mAbs

Parallelism experiments to evaluate matrix effects, selectivity and sensitivity in ligand-binding assay method development: pros and cons

(2017) Jing Tu et al.   Bioanalysis

Immunoaffinity LC–MS/MS for quantitative determination of a free and total protein target as a target engagement biomarker

(2017) Hongwei Zhang et al.   Bioanalysis

Workshop Report: Crystal City VI—Bioanalytical Method Validation for Biomarkers

(2016) Mark E. Arnold et al.   AAPS Journal

Quantitative Analysis of Human Neonatal Fc Receptor (FcRn) Tissue Expression in Transgenic Mice by Online Peptide Immuno-Affinity LC-HRMS

(2016) Yao-Yun Fan et al.   ANALYTICAL CHEMISTRY

Automated Microchromatography Enables Multiplexing of Immunoaffinity Enrichment of Peptides to Greater than 150 for Targeted MS-Based Assays

(2016) Paul J. Ippoliti et al.   ANALYTICAL CHEMISTRY

A high-throughput mass spectrometry assay to simultaneously measure intact insulin and C-peptide

(2016) Steven W. Taylor et al.   CLINICA CHIMICA ACTA

Comprehensive Assessment of M-Proteins Using Nanobody Enrichment Coupled to MALDI-TOF Mass Spectrometry

(2016) J. R. Mills et al.   CLINICAL CHEMISTRY

Surrogate analyte approach for quantitation of endogenous NAD+ in human acidified blood samples using liquid chromatography coupled with electrospray ionization tandem mass spectrometry

(2016) Liling Liu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Tissue expression profile of human neonatal Fc receptor (FcRn) in Tg32 transgenic mice

(2016) Yao-Yun Fan et al.   mAbs

Simultaneous Proteomic Discovery and Targeted Monitoring using Liquid Chromatography, Ion Mobility Spectrometry, and Mass Spectrometry

(2016) Kristin E. Burnum-Johnson et al.   MOLECULAR & CELLULAR PROTEOMICS

Six alternative proteases for mass spectrometry–based proteomics beyond trypsin

(2016) Piero Giansanti et al.   Nature Protocols

High precision quantification of human plasma proteins using the automated SISCAPA Immuno-MS workflow

(2016) Morteza Razavi et al.   New Biotechnology

Quantitative measurements of GDF-8 using immunoaffinity LC-MS/MS

(2016) Joe Palandra et al.   Proteomics Clinical Applications

Quantitative analysis of factor P (Properdin) in monkey serum using immunoaffinity capturing in combination with LC–MS/MS

(2016) Xinliu Gao et al.   Bioanalysis

Multiplexed longitudinal measurement of protein biomarkers in DBS using an automated SISCAPA workflow

(2016) Morteza Razavi et al.   Bioanalysis

Ultrasensitive quantitative LC–MS/MS of an inhibitor of apoptosis protein's antagonist in plasma using protein target affinity extraction

(2016) Lorell N Discenza et al.   Bioanalysis

Quantification of protein biomarkers in tissues: new capabilities with pellet digestion peptide immunoaffinity LC–MS/MS

(2016) Hendrik Neubert et al.   Bioanalysis

Characterization and quantification of oxyntomodulin in human and rat plasma using high-resolution accurate mass LC–MS

(2016) Jennifer M Cox et al.   Bioanalysis

Development and validation of an IA-LC/MS method to quantitate active and total B-type natriuretic peptide in human plasma

(2016) Derek L Chappell et al.   Bioanalysis

An evaluation of an aptamer for use as an affinity reagent with MS: PCSK9 as an example protein

(2016) Vinita Gupta et al.   Bioanalysis

Parallelism experiments in biomarker ligand-binding assays to assess immunological similarity

(2016) Lindsay E King   Bioanalysis

LC–MS quantification of protein drugs: validating protein LC–MS methods with predigestion immunocapture

(2016) Jeffrey Duggan et al.   Bioanalysis

Large-scale implementation of sequential protein and peptide immunoaffinity enrichment LC/nanoLC–MS/MS for human β-nerve growth factor

(2016) Gary A Schultz et al.   Bioanalysis

Quantitative Performance of Internal Standard Platforms for Absolute Protein Quantification Using Multiple Reaction Monitoring-Mass Spectrometry

(2015) Kerry Bauer Scott et al.   ANALYTICAL CHEMISTRY

Quantitative assessment of human serum transferrin receptor in breast cancer patients pre- and post-chemotherapy using peptide immunoaffinity enrichment coupled with targeted proteomics

(2015) Qingqing Xu et al.   CLINICA CHIMICA ACTA

LC-MS/MS Measurement of Parathyroid Hormone-Related Peptide

(2015) M. M. Kushnir et al.   CLINICAL CHEMISTRY

Multiplexed Quantification of Proglucagon-Derived Peptides by Immunoaffinity Enrichment and Tandem Mass Spectrometry after a Meal Tolerance Test

(2015) A. Y. H. Lee et al.   CLINICAL CHEMISTRY

Recommendations for the Generation, Quantification, Storage, and Handling of Peptides Used for Mass Spectrometry-Based Assays

(2015) A. N. Hoofnagle et al.   CLINICAL CHEMISTRY

Applications of MALDI Mass Spectrometry in Clinical Chemistry

(2015) M. W. Duncan et al.   CLINICAL CHEMISTRY

Measurement by a Novel LC-MS/MS Methodology Reveals Similar Serum Concentrations of Vitamin D-Binding Protein in Blacks and Whites

(2015) C. M. Henderson et al.   CLINICAL CHEMISTRY

Automated Multiplex LC-MS/MS Assay for Quantifying Serum Apolipoproteins A-I, B, C-I, C-II, C-III, and E with Qualitative Apolipoprotein E Phenotyping

(2015) I. van den Broek et al.   CLINICAL CHEMISTRY

Utility of free and total target measurements as target engagement and efficacy biomarkers in biotherapeutic development-Opportunities and challenges

(2015) Songmao Zheng et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Development of multiplex mass spectrometric immunoassay for detection and quantification of apolipoproteins C-I, C-II, C-III and their proteoforms

(2015) Olgica Trenchevska et al.   METHODS

Quantification of serum apolipoproteins A-I and B-100 in clinical samples using an automated SISCAPA–MALDI-TOF-MS workflow

(2015) Irene van den Broek et al.   METHODS

LC–MS-based quantification of intact proteins: perspective for clinical and bioanalytical applications

(2015) Irene van den Broek et al.   Bioanalysis

Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry

(2015) Frederik Weiß et al.   Scientific Reports

Ligand Binding Assay Critical Reagents and Their Stability: Recommendations and Best Practices from the Global Bioanalysis Consortium Harmonization Team

(2014) Lindsay E. King et al.   AAPS Journal

Recommendations for Validation of LC-MS/MS Bioanalytical Methods for Protein Biotherapeutics

(2014) Rand Jenkins et al.   AAPS Journal

Multiplexing Determination of Small Cell Lung Cancer Biomarkers and Their Isovariants in Serum by Immunocapture LC-MS/MS

(2014) Silje B. Torsetnes et al.   ANALYTICAL CHEMISTRY

Quantitative Analysis of Prostate Specific Antigen Isoforms Using Immunoprecipitation and Stable Isotope Labeling Mass Spectrometry

(2014) Yi-Ting Chen et al.   ANALYTICAL CHEMISTRY

Practical Immunoaffinity-Enrichment LC-MS for Measuring Protein Kinetics of Low-Abundance Proteins

(2014) M. E. Lassman et al.   CLINICAL CHEMISTRY

Quantification of Serum IgG Subclasses by Use of Subclass-Specific Tryptic Peptides and Liquid Chromatography-Tandem Mass Spectrometry

(2014) P. M. Ladwig et al.   CLINICAL CHEMISTRY

From Lost in Translation to Paradise Found: Enabling Protein Biomarker Method Transfer by Mass Spectrometry

(2014) R. P. Grant et al.   CLINICAL CHEMISTRY

Immunoextraction-Tandem Mass Spectrometry Method for Measuring Intact Human Chorionic Gonadotropin, Free  -Subunit, and  -Subunit Core Fragment in Urine

(2014) G. A. Woldemariam et al.   CLINICAL CHEMISTRY

Quantification of Tau in Cerebrospinal Fluid by Immunoaffinity Enrichment and Tandem Mass Spectrometry

(2014) T. McAvoy et al.   CLINICAL CHEMISTRY

Mass Spectrometry-Based Candidate Reference Measurement Procedure for Quantification of Amyloid-  in Cerebrospinal Fluid

(2014) A. Leinenbach et al.   CLINICAL CHEMISTRY

High-Affinity Recombinant Antibody Fragments (Fabs) Can Be Applied in Peptide Enrichment Immuno-MRM Assays

(2014) Jeffrey R. Whiteaker et al.   JOURNAL OF PROTEOME RESEARCH

Metrological traceability in mass spectrometry-based targeted protein quantitation: A proof-of-principle study for serum apolipoproteins A-I and B100

(2014) Nico P.M. Smit et al.   Journal of Proteomics

Single-step Enrichment by Ti4+-IMAC and Label-free Quantitation Enables In-depth Monitoring of Phosphorylation Dynamics with High Reproducibility and Temporal Resolution

(2014) Erik L. de Graaf et al.   MOLECULAR & CELLULAR PROTEOMICS

Mass spectrometry based biomarker discovery, verification, and validation - Quality assurance and control of protein biomarker assays

(2014) Carol E. Parker et al.   Molecular Oncology

Serum β-nerve growth factor concentrations in pregnant female, nonpregnant female, and male cynomolgus monkeys

(2014) Hendrik Neubert et al.   NEUROREPORT

Parallel Workflow for High-Throughput (>1,000 Samples/Day) Quantitative Analysis of Human Insulin-Like Growth Factor 1 Using Mass Spectrometric Immunoassay

(2014) Paul E. Oran et al.   PLoS One

Mass Spectrometric Immunoassay for the qualitative and quantitative analysis of the cytokine Macrophage Migration Inhibitory Factor (MIF)

(2014) Nisha D Sherma et al.   Proteome Science

Quantitative proteomics using the high resolution accurate mass capabilities of the quadrupole-orbitrap mass spectrometer

(2014) Sebastien Gallien et al.   Bioanalysis

Parallelism: considerations for the development, validation and implementation of PK and biomarker ligand-binding assays

(2014) Lauren F Stevenson et al.   Bioanalysis

Development of a high-throughput UHPLC–MS/MS (SRM) method for the quantitation of endogenous glucagon from human plasma

(2014) James W Howard et al.   Bioanalysis

Highly Specific and Sensitive Measurements of Human and Monkey Interleukin 21 Using Sequential Protein and Tryptic Peptide Immunoaffinity LC-MS/MS

(2013) Joe Palandra et al.   ANALYTICAL CHEMISTRY

Fully Validated LC-MS/MS Assay for the Simultaneous Quantitation of Coadministered Therapeutic Antibodies in Cynomolgus Monkey Serum

(2013) Hao Jiang et al.   ANALYTICAL CHEMISTRY

Multidimensional LC-MS/MS Enables Simultaneous Quantification of Intact Human Insulin and Five Recombinant Analogs in Human Plasma

(2013) Erin E. Chambers et al.   ANALYTICAL CHEMISTRY

Rapid development of sensitive, high-throughput, quantitative and highly selective mass spectrometric targeted immunoassays for clinically important proteins in human plasma and serum

(2013) Bryan Krastins et al.   CLINICAL BIOCHEMISTRY

Quantification of a Proteotypic Peptide from Protein C Inhibitor by Liquid Chromatography-Free SISCAPA-MALDI Mass Spectrometry: Application to Identification of Recurrence of Prostate Cancer

(2013) M. Razavi et al.   CLINICAL CHEMISTRY

Measurement of Thyroglobulin by Liquid Chromatography-Tandem Mass Spectrometry in Serum and Plasma in the Presence of Antithyroglobulin Autoantibodies

(2013) M. M. Kushnir et al.   CLINICAL CHEMISTRY

Quantification of free and total desmosine and isodesmosine in human urine by liquid chromatography tandem mass spectrometry: A comparison of the surrogate-analyte and the surrogate-matrix approach for quantitation

(2013) Sara Ongay et al.   JOURNAL OF CHROMATOGRAPHY A

High sensitivity LC–MS/MS method for direct quantification of human parathyroid 1–34 (teriparatide) in human plasma

(2013) Erin E. Chambers et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Evaluation of Interspecimen Trypsin Digestion Efficiency Prior to Multiple Reaction Monitoring-Based Absolute Protein Quantification with Native Protein Calibrators

(2013) Irene van den Broek et al.   JOURNAL OF PROTEOME RESEARCH

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Improved Mass Spectrometry Assay For Plasma Hepcidin: Detection and Characterization of a Novel Hepcidin Isoform

(2013) Coby M. M. Laarakkers et al.   PLoS One

Mass spectrometric immunoassay and MRM as targeted MS-based quantitative approaches in biomarker development: Potential applications to cardiovascular disease and diabetes

(2013) Hussein Yassine et al.   Proteomics Clinical Applications

A Blood-Based Proteomic Classifier for the Molecular Characterization of Pulmonary Nodules

(2013) X.-j. Li et al.   Science Translational Medicine

Characterization of critical reagents in ligand-binding assays: enabling robust bioanalytical methods and lifecycle management

(2013) Brian J Geist et al.   Bioanalysis

2013 White Paper on recent issues in bioanalysis: ‘hybrid’ – the best of LBA and LCMS

(2013) Lauren Stevenson et al.   Bioanalysis

High-Throughput Method Development for Sensitive, Accurate, and Reproducible Quantification of Therapeutic Monoclonal Antibodies in Tissues Using Orthogonal Array Optimization and Nano Liquid Chromatography/Selected Reaction Monitoring Mass Spectrometry

(2012) Xiaotao Duan et al.   ANALYTICAL CHEMISTRY

Sequential Protein and Peptide Immunoaffinity Capture for Mass Spectrometry-Based Quantification of Total Human β-Nerve Growth Factor

(2012) Hendrik Neubert et al.   ANALYTICAL CHEMISTRY

As Sample Prep Improves, So Does Mass Spec

(2012) John Russell   Genetic Engineering & Biotechnology News

Nano-scale liquid chromatography/mass spectrometry and on-the-fly orthogonal array optimization for quantification of therapeutic monoclonal antibodies and the application in preclinical analysis

(2012) Xiaotao Duan et al.   JOURNAL OF CHROMATOGRAPHY A

Characterizing Ubiquitination Sites by Peptide-based Immunoaffinity Enrichment

(2012) Daisy Bustos et al.   MOLECULAR & CELLULAR PROTEOMICS

Clinical Utility of Insulin-Like Growth Factor 1 and 2; Determination by High Resolution Mass Spectrometry

(2012) Cory Bystrom et al.   PLoS One

Comparison of the quantification of a therapeutic protein using nominal and accurate mass MS/MS

(2012) Robert S Plumb et al.   Bioanalysis

Development and validation of an ultra-sensitive method for the measurement of plasma renin activity in human plasma via LC–MS/MS

(2012) Derek L Chappell et al.   Bioanalysis

Surrogate matrix and surrogate analyte approaches for definitive quantitation of endogenous biomolecules

(2012) Barry R Jones et al.   Bioanalysis

Bioanalytical Approaches to Quantify “Total” and “Free” Therapeutic Antibodies and Their Targets: Technical Challenges and PK/PD Applications Over the Course of Drug Development

(2011) Jean W. Lee et al.   AAPS Journal

Quantitation of amyloid beta peptides Aβ1–38, Aβ1–40, and Aβ1–42 in human cerebrospinal fluid by ultra-performance liquid chromatography–tandem mass spectrometry

(2011) Mary E. Lame et al.   ANALYTICAL BIOCHEMISTRY

Narrow Mass Extraction of Time-of-Flight Data for Quantitative Analysis of Proteins: Determination of Insulin-Like Growth Factor-1

(2011) Cory E. Bystrom et al.   ANALYTICAL CHEMISTRY

An immunoaffinity liquid chromatography–tandem mass spectrometry assay for the quantitation of matrix metalloproteinase 9 in mouse serum

(2010) Mireia Fernández Ocaña et al.   ANALYTICAL BIOCHEMISTRY

Immunoprecipitation on magnetic beads and liquid chromatography–tandem mass spectrometry for carbonic anhydrase II quantification in human serum

(2010) Luciano Callipo et al.   ANALYTICAL BIOCHEMISTRY

Online High-Flow Peptide Immunoaffinity Enrichment and Nanoflow LC-MS/MS: Assay Development for Total Salivary Pepsin/Pepsinogen

(2010) H. Neubert et al.   CLINICAL CHEMISTRY

Plasma Renin Activity by LC-MS/MS: Development of a Prototypical Clinical Assay Reveals a Subpopulation of Human Plasma Samples with Substantial Peptidase Activity

(2010) C. E. Bystrom et al.   CLINICAL CHEMISTRY

Validation and application of an LC–MS/MS method for quantitation of three fatty acid ethanolamides as biomarkers for fatty acid hydrolase inhibition in human plasma

(2010) Wenying Jian et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

A Quantitative Study of the Effects of Chaotropic Agents, Surfactants, and Solvents on the Digestion Efficiency of Human Plasma Proteins by Trypsin

(2010) Jennifer L. Proc et al.   JOURNAL OF PROTEOME RESEARCH

Method validation and application of protein biomarkers: basic similarities and differences from biotherapeutics

(2010) Jean W Lee   Bioanalysis

Generic approach to validation of small-molecule LC–MS/MS biomarker assays

(2010) Richard Houghton et al.   Bioanalysis

Stable-isotope dilution LC–MS for quantitative biomarker analysis

(2010) Eugene Ciccimaro et al.   Bioanalysis

Automated Detection of Inaccurate and Imprecise Transitions in Peptide Quantification by Multiple Reaction Monitoring Mass Spectrometry

(2009) S. E. Abbatiello et al.   CLINICAL CHEMISTRY

The fundamental flaws of immunoassays and potential solutions using tandem mass spectrometry

(2009) Andrew N. Hoofnagle et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Multiple Reaction Monitoring-based, Multiplexed, Absolute Quantitation of 45 Proteins in Human Plasma

(2009) Michael A. Kuzyk et al.   MOLECULAR & CELLULAR PROTEOMICS

How specific is my SRM?: The issue of precursor and product ion redundancy

(2009) Jamie Sherman et al.   PROTEOMICS

Detection of Endogenous B-Type Natriuretic Peptide at Very Low Concentrations in Patients With Heart Failure

(2008) Eric E. Niederkofler et al.   Circulation-Heart Failure

Pitfalls and Prevention Strategies for Liquid Chromatography-Tandem Mass Spectrometry in the Selected Reaction- Monitoring Mode for Drug Analysis

(2008) F.-L. Sauvage et al.   CLINICAL CHEMISTRY

Quantification of Thyroglobulin, a Low-Abundance Serum Protein, by Immunoaffinity Peptide Enrichment and Tandem Mass Spectrometry

(2008) A. N. Hoofnagle et al.   CLINICAL CHEMISTRY

The SCX/IMAC enrichment approach for global phosphorylation analysis by mass spectrometry

(2008) Judit Villén et al.   Nature Protocols

Quantification of human insulin-like growth factor-1 and qualitative detection of its analogues in plasma using liquid chromatography/electrospray ionisation tandem mass spectrometry

(2008) Michael Bredehöft et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Enrichment of low molecular weight serum proteins using acetonitrile precipitation for mass spectrometry based proteomic analysis

(2008) Richard Kay et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY