Light‐Activated Rhenium Complexes with Dual Mode of Action against Bacteria

Polymyxin Derivatives that Sensitize Gram-Negative Bacteria to Other Antibiotics

(2019) Martti Vaara   MOLECULES

The Infectious Diseases Society of America’s 10 × ’20 Initiative (Ten New Systemic Antibacterial Agents FDA-approved by 2020): Is 20 × ’20 a Possibility?

(2019) George H Talbot et al.   CLINICAL INFECTIOUS DISEASES

Using Nanoscopy To Probe the Biological Activity of Antimicrobial Leads That Display Potent Activity against Pathogenic, Multidrug Resistant, Gram-Negative Bacteria

(2019) Kirsty L. Smitten et al.   ACS Nano

Bio‐Organometallic Derivatives of Antibacterial Drugs

(2019) Miguel A. Sierra et al.   CHEMISTRY-A EUROPEAN JOURNAL

A CuAAC Click Approach for the Introduction of Bidentate Metal Complexes to a Sulfanilamide-Derived Antibiotic Fragment

(2019) Reece G. Miller et al.   INORGANIC CHEMISTRY

Deciphering molecular mechanism of silver by integrated omic approaches enables enhancing its antimicrobial efficacy in E. coli

(2019) Haibo Wang et al.   PLOS BIOLOGY

Selective photoinactivation of methicillin‐resistant Staphylococcus aureus by highly positively charged Ru(II) complexes

(2019) Yang Feng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organometallic and coordination rhenium compounds and their potential in cancer therapy

(2019) Elisabeth B. Bauer et al.   COORDINATION CHEMISTRY REVIEWS

Prospective study on human fecal carriage of Enterobacteriaceae possessing mcr-1 and mcr-2 genes in a regional hospital in Hong Kong

(2018) Wai-Sing Chan et al.   BMC INFECTIOUS DISEASES

Anticancer activity of complexes of the third row transition metals, rhenium, osmium, and iridium

(2018) Chilaluck C. Konkankit et al.   DALTON TRANSACTIONS

Spectrofluorimetric quantification of antibiotic drug concentration in bacterial cells for the characterization of translocation across bacterial membranes

(2018) Julia Vergalli et al.   Nature Protocols

Sublethal Photodynamic Treatment Does Not Lead to Development of Resistance

(2018) Rawan Al-Mutairi et al.   Frontiers in Microbiology

Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433

(2018) Susan Monro et al.   CHEMICAL REVIEWS

Ru(II)-Complex-Based DNA Photocleaver Having Intense Absorption in the Phototherapeutic Window

(2017) Yangyang Zhang et al.   INORGANIC CHEMISTRY

Antimicrobial Properties of Mono- and Di-fac-rhenium Tricarbonyl 2-Pyridyl-1,2,3-triazole Complexes

(2016) Sreedhar V. Kumar et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

A Gestalt approach to Gram-negative entry

(2016) Lynn L. Silver   BIOORGANIC & MEDICINAL CHEMISTRY

Evolving medicinal chemistry strategies in antibiotic discovery

(2016) Andrew C Pawlowski et al.   CURRENT OPINION IN BIOTECHNOLOGY

Antibiotics in the clinical pipeline at the end of 2015

(2016) Mark S Butler et al.   JOURNAL OF ANTIBIOTICS

Membrane Insertion of a Dinuclear Polypyridylruthenium(II) Complex Revealed by Solid-State NMR and Molecular Dynamics Simulation: Implications for Selective Antibacterial Activity

(2016) Daniel K. Weber et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A bivalent cationic dye enabling selective photo-inactivation against Gram-negative bacteria

(2015) Ke Li et al.   CHEMICAL COMMUNICATIONS

Ruthenium complexes as antimicrobial agents

(2015) Fangfei Li et al.   CHEMICAL SOCIETY REVIEWS

An organometallic structure-activity relationship study reveals the essential role of a Re(CO)3 moiety in the activity against gram-positive pathogens including MRSA

(2015) Malay Patra et al.   Chemical Science

Synthesis, Spectroscopic, and Photophysical Characterization and Photosensitizing Activity toward Prokaryotic and Eukaryotic Cells of Porphyrin-Magainin and -Buforin Conjugates

(2014) Ryan Dosselli et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis, Characterization, and Biological Evaluation of New Ru(II) Polypyridyl Photosensitizers for Photodynamic Therapy

(2014) Angelo Frei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Selective Photodynamic Inactivation of Bacterial Cells over Mammalian Cells by New Triarylmethanes

(2014) Ke Li et al.   LANGMUIR

[Re(CO)3]+ Complexes of exo-Functionalized Tridentate “Click” Macrocycles: Synthesis, Stability, Photophysical Properties, Bioconjugation, and Antibacterial Activity

(2014) Asif Noor et al.   ORGANOMETALLICS

In VitroPhotodynamic Inactivation Effects of Ru(II) Complexes on Clinical Methicillin-resistantStaphylococcus aureusPlanktonic and Biofilm Cultures

(2014) Yucheng Wang et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Analysis of the Mechanism of Action of Potent Antibacterial Hetero-tri-organometallic Compounds: A Structurally New Class of Antibiotics

(2013) Michaela Wenzel et al.   ACS Chemical Biology

Chlorido-containing ruthenium(ii) and iridium(iii) complexes as antimicrobial agents

(2013) Mallesh Pandrala et al.   DALTON TRANSACTIONS

Towards cancer cell-specific phototoxic organometallic rhenium(i) complexes

(2013) Anna Leonidova et al.   DALTON TRANSACTIONS

The antimalarial ferroquine: from bench to clinic

(2013) C. Biot et al.   Parasite

Photodynamic inactivation of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus with Ru(II)-based type I/type II photosensitizers

(2013) Yaxal Arenas et al.   Photodiagnosis and Photodynamic Therapy

Fe-S Cluster Biosynthesis Controls Uptake of Aminoglycosides in a ROS-Less Death Pathway

(2013) B. Ezraty et al.   SCIENCE

Dinuclear ruthenium(ii) antimicrobial agents that selectively target polysomes in vivo

(2013) Fangfei Li et al.   Chemical Science

Small organometallic compounds as antibacterial agents

(2012) Malay Patra et al.   DALTON TRANSACTIONS

Synthesis, Characterization, and Photoinduced Antibacterial Activity of Porphyrin-Type Photosensitizers Conjugated to the Antimicrobial Peptide Apidaecin 1b

(2012) Ryan Dosselli et al.   JOURNAL OF MEDICINAL CHEMISTRY

The antimicrobial activity of inert oligonuclear polypyridylruthenium(ii) complexes against pathogenic bacteria, including MRSA

(2011) Fangfei Li et al.   DALTON TRANSACTIONS

Continuous real-time monitoring of cationic porphyrin-induced photodynamic inactivation of bacterial membrane functions using electrochemical sensors

(2011) Keiko Komagoe et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Alterations of Escherichia coli envelope as a consequence of photosensitization with tetrakis(N-ethylpyridinium-4-yl)porphyrin tetratosylate

(2011) Birute Pudziuvyte et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Sequential insertion of three different organometallics into a versatile building block containing a PNA backbone

(2010) Malay Patra et al.   DALTON TRANSACTIONS

Antimicrobial activity of ruthenium-based intercalators

(2010) Albert Bolhuis et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Light Induced Antimicrobial Properties of a Brominated Boron Difluoride (BF2) Chelated Tetraarylazadipyrromethene Photosensitizer

(2010) Daniel O. Frimannsson et al.   JOURNAL OF MEDICINAL CHEMISTRY

High-resolution animal PET imaging of prostate cancer xenografts with three different 64Cu-labeled antibodies against native cell-adherent PSMA

(2010) Karen Alt et al.   PROSTATE

Photodynamic therapy for localized infections—State of the art

(2009) Tianhong Dai et al.   Photodiagnosis and Photodynamic Therapy

Meropenem

(2008) Claudine M Baldwin et al.   DRUGS