Cancer-FOXP3 directly activated CCL5 to recruit FOXP3+Treg cells in pancreatic ductal adenocarcinoma

Current progress in immunotherapy for pancreatic cancer

(2016) Kelly Foley et al.   CANCER LETTERS

Downregulation of FOXP3 inhibits invasion and immune escape in cholangiocarcinoma

(2015) Chao Ma et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Phase Ia Study of FoxP3+ CD4 Treg Depletion by Infusion of a Humanized Anti-CCR4 Antibody, KW-0761, in Cancer Patients

(2015) K. Kurose et al.   CLINICAL CANCER RESEARCH

Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma

(2015) Tiansuo Zhao et al.   Oncotarget

The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer

(2014) S T Ward et al.   BRITISH JOURNAL OF CANCER

Transient Ablation of Regulatory T cells Improves Antitumor Immunity in Colitis-Associated Colon Cancer

(2014) E. Pastille et al.   CANCER RESEARCH

Foxp3+ T Cells Inhibit Antitumor Immune Memory Modulated by mTOR Inhibition

(2014) Yanping Wang et al.   CANCER RESEARCH

Human Circulating CD4+CD25highFoxp3+ Regulatory T Cells Kill Autologous CD8+ but Not CD4+ Responder Cells by Fas-Mediated Apoptosis

(2014) L. Strauss et al.   JOURNAL OF IMMUNOLOGY

Disruption of CCR5-Dependent Homing of Regulatory T Cells Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer

(2014) M. C. B. Tan et al.   JOURNAL OF IMMUNOLOGY

An Increased Abundance of Tumor-Infiltrating Regulatory T Cells Is Correlated with the Progression and Prognosis of Pancreatic Ductal Adenocarcinoma

(2014) Yichen Tang et al.   PLoS One

The pancreatic cancer microenvironment: an immunologic battleground

(2014) Venu G Pillarisetty   OncoImmunology

Priming the pancreatic cancer tumor microenvironment for checkpoint-inhibitor immunotherapy

(2014) Eric R Lutz et al.   OncoImmunology

Immune cell infiltration as an indicator of the immune microenvironment of pancreatic cancer

(2013) Y Ino et al.   BRITISH JOURNAL OF CANCER

Inflammatory networks and immune surveillance of pancreatic carcinoma

(2013) Robert H Vonderheide et al.   CURRENT OPINION IN IMMUNOLOGY

Activated Pancreatic Stellate Cells Sequester CD8+ T Cells to Reduce Their Infiltration of the Juxtatumoral Compartment of Pancreatic Ductal Adenocarcinoma

(2013) Abasi Ene–Obong et al.   GASTROENTEROLOGY

TGF-β-miR-34a-CCL22 Signaling-Induced Treg Cell Recruitment Promotes Venous Metastases of HBV-Positive Hepatocellular Carcinoma

(2012) Pengyuan Yang et al.   CANCER CELL

T-Regulatory Cells: Key Players in Tumor Immune Escape and Angiogenesis

(2012) A. Facciabene et al.   CANCER RESEARCH

The Prognostic Value of FoxP3+ Tumor-Infiltrating Lymphocytes in Cancer: A Critical Review of the Literature

(2012) R. J. deLeeuw et al.   CLINICAL CANCER RESEARCH

FOXP3 expression in tumor cells and implications for cancer progression

(2012) Tiziana Triulzi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor-Infiltrating Monocytic Myeloid-Derived Suppressor Cells Mediate CCR5-Dependent Recruitment of Regulatory T Cells Favoring Tumor Growth

(2012) E. Schlecker et al.   JOURNAL OF IMMUNOLOGY

Innate immune recognition of breast tumor cells mediates CCL22 secretion favoring Treg recruitment within tumor environment

(2012) Christine Ménétrier-Caux et al.   OncoImmunology

CXCL12/CXCR4 Blockade Induces Multimodal Antitumor Effects That Prolong Survival in an Immunocompetent Mouse Model of Ovarian Cancer

(2011) E. Righi et al.   CANCER RESEARCH

Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells

(2011) Andrea Facciabene et al.   NATURE

Checkpoint control and cancer

(2011) R H Medema et al.   ONCOGENE

Circulating CD4+CD25+ Regulatory T Cells in Patients With Pancreatic Cancer

(2011) Tomohisa Yamamoto et al.   PANCREAS

Dendritic Cell Vaccination in Combination with Anti-CD25 Monoclonal Antibody Treatment: A Phase I/II Study in Metastatic Melanoma Patients

(2010) J. F. M. Jacobs et al.   CLINICAL CANCER RESEARCH

Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma

(2010) Richard E. Royal et al.   JOURNAL OF IMMUNOTHERAPY

Human FOXP3 and cancer

(2010) F Martin et al.   ONCOGENE

FOXP3 Defines Regulatory T Cells in Human Tumor and Autoimmune Disease

(2009) I. Kryczek et al.   CANCER RESEARCH

Immunomodulation of FOXP3+ Regulatory T Cells by the Aromatase Inhibitor Letrozole in Breast Cancer Patients

(2009) D. Generali et al.   CLINICAL CANCER RESEARCH

CCL22 Recruits CD4-positive CD25-positive Regulatory T Cells into Malignant Pleural Effusion

(2009) X.-J. Qin et al.   CLINICAL CANCER RESEARCH

Effector/Memory but Not Naive Regulatory T Cells Are Responsible for the Loss of Concomitant Tumor Immunity

(2009) Yung-Chang Lin et al.   JOURNAL OF IMMUNOLOGY

Tumor-derived TGF-β Mediates Conversion of CD4+Foxp3+ Regulatory T Cells in a Murine Model of Pancreas Cancer

(2008) Tricia A. Moo-Young et al.   JOURNAL OF IMMUNOTHERAPY

Foxp3 expression in human cancer cells

(2008) Vaios Karanikas et al.   Journal of Translational Medicine

In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination

(2008) J. Bayry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T Cells: Mechanisms of Differentiation and Function

(2007) Steven Z. Josefowicz et al.   Annual Review of Immunology