Ectopia associated MN1 fusions and aberrant activation in myeloid neoplasms with t(12;22)(p13;q12)

A novel NPM1-RARG-NPM1 chimeric fusion in acute myeloid leukaemia resembling acute promyelocytic leukaemia but resistant to all-trans retinoic acid and arsenic trioxide

(2019) Xue Chen et al.   BRITISH JOURNAL OF CANCER

Analysis of overlapping heterozygous novel submicroscopic CNVs and FANCA–VPS9D1 fusion transcripts in a Fanconi anemia patient

(2019) Daijing Nie et al.   JOURNAL OF HUMAN GENETICS

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

(2019) Tim Pieters et al.   Scientific Reports

Trisomy 8 in acute myeloid leukemia

(2019) Anette Lodvir Hemsing et al.   Expert Review of Hematology

CSF3R mutations are frequently associated with abnormalities of RUNX1, CBFB, CEBPA, and NPM1 genes in acute myeloid leukemia

(2018) Yang Zhang et al.   CANCER

Identification of novel recurrent ETV6-IgH fusions in primary central nervous system lymphoma

(2018) Aurélie Bruno et al.   NEURO-ONCOLOGY

SEdb: a comprehensive human super-enhancer database

(2018) Yong Jiang et al.   NUCLEIC ACIDS RESEARCH

Acute Myeloid Leukemia, Version 3.2017, NCCN Clinical Practice Guidelines in Oncology

(2017) Margaret R. O'Donnell et al.   Journal of the National Comprehensive Cancer Network

ETV6 in hematopoiesis and leukemia predisposition

(2017) Hanno Hock et al.   SEMINARS IN HEMATOLOGY

The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia

(2016) D. A. Arber et al.   BLOOD

Myelodysplastic Syndromes, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology

(2016) Peter L. Greenberg et al.   Journal of the National Comprehensive Cancer Network

High MN1 expression increases the in vitro clonogenic activity of primary mouse B-cells

(2015) Masashi Numata et al.   LEUKEMIA RESEARCH

Mediator kinase inhibition further activates super-enhancer-associated genes in AML

(2015) Henry E. Pelish et al.   NATURE

MN1–Fli1 oncofusion transforms murine hematopoietic progenitor cells into acute megakaryoblastic leukemia cells

(2015) D V Wenge et al.   Oncogenesis

Genomic Dark Matter Sheds Light on EVI1-Driven Leukemia

(2014) Richard P. Koche et al.   CANCER CELL

A Remote GATA2 Hematopoietic Enhancer Drives Leukemogenesis in inv(3)(q21;q26) by Activating EVI1 Expression

(2014) Hiromi Yamazaki et al.   CANCER CELL

A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia

(2014) Stefan Gröschel et al.   CELL

The clinical characteristics and prognostic significance of MN1 gene and MN1-associated microRNA expression in adult patients with de novo acute myeloid leukemia

(2013) Lili Xiang et al.   ANNALS OF HEMATOLOGY

ETV6 fusion genes in hematological malignancies: A review

(2012) Etienne De Braekeleer et al.   LEUKEMIA RESEARCH

Establishment of a novel human myeloid leukemia cell line, AMU-AML1, carrying t(12;22)(p13;q11) without chimeric MN1-TEL and with high expression of MN1

(2011) Mayuko Gotou et al.   GENES CHROMOSOMES & CANCER

Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyperproliferation and restores myeloid differentiation

(2009) A. Kandilci et al.   BLOOD

The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes

(2009) J. W. Vardiman et al.   BLOOD

Prognostic Importance ofMN1Transcript Levels, and Biologic Insights FromMN1-Associated Gene and MicroRNA Expression Signatures in Cytogenetically Normal Acute Myeloid Leukemia: A Cancer and Leukemia Group B Study

(2009) Christian Langer et al.   JOURNAL OF CLINICAL ONCOLOGY