Predicting associations among drugs, targets and diseases by tensor decomposition for drug repositioning

Computational Drug Repositioning for Gastric Cancer using Reversal Gene Expression Profiles

(2019) In-Wha Kim et al.   Scientific Reports

Drug repositioning through integration of prior knowledge and projections of drugs and diseases

(2019) Ping Xuan et al.   BIOINFORMATICS

Computational drug repositioning using low-rank matrix approximation and randomized algorithms

(2018) Huimin Luo et al.   BIOINFORMATICS

Nano-engineering of biomedical prednisolone liposomes: evaluation of the cytotoxic effect on human colon carcinoma cell lines

(2018) Cristina Lorente et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Interaction of antidiabetic α-glucosidase inhibitors and gut bacteria α-glucosidase

(2018) Kemin Tan et al.   PROTEIN SCIENCE

Galantamine anti-colitic effect: Role of alpha-7 nicotinic acetylcholine receptor in modulating Jak/STAT3, NF-κB/HMGB1/RAGE and p-AKT/Bcl-2 pathways

(2018) Shakeeb A. Wazea et al.   Scientific Reports

Use of N-nitrosodimethylamine (NDMA) contaminated valsartan products and risk of cancer: Danish nationwide cohort study

(2018) Anton Pottegård et al.   BMJ-British Medical Journal

Drug repositioning using drug-disease vectors based on an integrated network

(2018) Taekeon Lee et al.   BMC BIOINFORMATICS

Computational drug repositioning using meta-path-based semantic network analysis

(2018) Zhen Tian et al.   BMC Systems Biology

Pathway-Based Drug Repositioning for Cancers: Computational Prediction and Experimental Validation

(2018) Michio Iwata et al.   JOURNAL OF MEDICINAL CHEMISTRY

New approach for understanding genome variations in KEGG

(2018) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Accurate Drug Repositioning through Non-tissue-Specific Core Signatures from Cancer Transcriptomes

(2018) Chi Xu et al.   Cell Reports

Deep-Learning-Based Drug–Target Interaction Prediction

(2017) Ming Wen et al.   JOURNAL OF PROTEOME RESEARCH

Tumor microenvironment confers mTOR inhibitor resistance in invasive intestinal adenocarcinoma

(2017) T Fujishita et al.   ONCOGENE

Using a novel computational drug-repositioning approach (DrugPredict) to rapidly identify potent drug candidates for cancer treatment

(2017) A B Nagaraj et al.   ONCOGENE

A network integration approach for drug-target interaction prediction and computational drug repositioning from heterogeneous information

(2017) Yunan Luo et al.   Nature Communications

Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data

(2016) Alexander Aliper et al.   MOLECULAR PHARMACEUTICS

Can you teach old drugs new tricks?

(2016) Nicola Nosengo   NATURE

Target-Based Drug Repositioning Using Large-Scale Chemical–Protein Interactome Data

(2015) Ryusuke Sawada et al.   Journal of Chemical Information and Modeling

Arsenic downregulates gene expression at the postsynaptic density in mouse cerebellum, including genes responsible for long-term potentiation and depression

(2014) Cong Zhang et al.   TOXICOLOGY LETTERS

Focus on mTOR inhibitors and tacrolimus in renal transplantation: Pharmacokinetics, exposure–response relationships, and clinical outcomes

(2014) Fuad Shihab et al.   TRANSPLANT IMMUNOLOGY

Drug–target interaction prediction through domain-tuned network-based inference

(2013) Salvatore Alaimo et al.   BIOINFORMATICS

Predicting Drug–Target Interactions Using Probabilistic Matrix Factorization

(2013) Murat Can Cobanoglu et al.   Journal of Chemical Information and Modeling

Predicting Drug-Target Interactions for New Drug Compounds Using a Weighted Nearest Neighbor Profile

(2013) Twan van Laarhoven et al.   PLoS One

Drug–target interaction prediction by learning from local information and neighbors

(2012) Jian-Ping Mei et al.   BIOINFORMATICS

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug

(2012) Hee Lee et al.   BMC Systems Biology

Drug–target interaction prediction by random walk on the heterogeneous network

(2012) Xing Chen et al.   Molecular BioSystems

The Comparative Toxicogenomics Database: update 2013

(2012) Allan Peter Davis et al.   NUCLEIC ACIDS RESEARCH

Malignant Transformation of Rat Kidney Induced by Environmental Substances and Estrogen

(2012) Susana Alfaro-Lira et al.   International Journal of Environmental Research and Public Health

Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

(2012) Feixiong Cheng et al.   PLoS Computational Biology