Network architecture strongly influences the fluid flow pattern through the lacunocanalicular network in human osteons

Towards a Connectomic Description of the Osteocyte Lacunocanalicular Network in Bone

(2019) Richard Weinkamer et al.   Current Osteoporosis Reports

The contribution of the pericanalicular matrix to mineral content in human osteonal bone

(2019) A. Roschger et al.   BONE

Integrins in Osteocyte Biology and Mechanotransduction

(2019) Ivor P. Geoghegan et al.   Current Osteoporosis Reports

Microstructural changes associated with osteoporosis negatively affect loading-induced fluid flow around osteocytes in cortical bone

(2018) Vittorio Gatti et al.   JOURNAL OF BIOMECHANICS

Understanding Age-Induced Cortical Porosity in Women: The Accumulation and Coalescence of Eroded Cavities Upon Existing Intracortical Canals Is the Main Contributor

(2018) Christina Møller Andreasen et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Brief communication: Test of a method to identify double-zonal osteon in polarized light microscopy

(2018) Emeline Raguin et al.   AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY

Coalignment of osteocyte canaliculi and collagen fibers in human osteonal bone

(2017) Felix Repp et al.   JOURNAL OF STRUCTURAL BIOLOGY

Osteocyte calcium signals encode strain magnitude and loading frequency in vivo

(2017) Karl J. Lewis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aging, Osteocytes, and Mechanotransduction

(2017) Haniyeh Hemmatian et al.   Current Osteoporosis Reports

Osteocyte Mechanobiology

(2017) Yuhei Uda et al.   Current Osteoporosis Reports

Mathematically modeling fluid flow and fluid shear stress in the canaliculi of a loaded osteon

(2016) Xiaogang Wu et al.   Biomedical Engineering Online

Three-dimensional reconstruction of Haversian systems in human cortical bone using synchrotron radiation-based micro-CT: morphology and quantification of branching and transverse connections across age

(2016) Isabel S. Maggiano et al.   JOURNAL OF ANATOMY

Single molecule force measurements of perlecan/HSPG2: A key component of the osteocyte pericellular matrix

(2016) Sithara S. Wijeratne et al.   MATRIX BIOLOGY

The Formation of Calcified Nanospherites during Micropetrosis Represents a Unique Mineralization Mechanism in Aged Human Bone

(2016) Petar Milovanovic et al.   Small

Monitoring in vivo (re)modeling: A computational approach using 4D microCT data to quantify bone surface movements

(2015) Annette I. Birkhold et al.   BONE

Quantifying the osteocyte network in the human skeleton

(2015) Pascal R. Buenzli et al.   BONE

Blood and interstitial flow in the hierarchical pore space architecture of bone tissue

(2015) Stephen C. Cowin et al.   JOURNAL OF BIOMECHANICS

Bone adaptation to cyclic loading in murine caudal vertebrae is maintained with age and directly correlated to the local micromechanical environment

(2015) Floor M. Lambers et al.   JOURNAL OF BIOMECHANICS

Aging Leads to a Dysregulation in Mechanically Driven Bone Formation and Resorption

(2015) Hajar Razi et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Synchrotron X-ray phase nano-tomography-based analysis of the lacunar–canalicular network morphology and its relation to the strains experienced by osteocytes in situ as predicted by case-specific finite element analysis

(2014) Peter Varga et al.   Biomechanics and Modeling in Mechanobiology

Bone cell mechanosensation of fluid flow stimulation: a fluid–structure interaction model characterising the role integrin attachments and primary cilia

(2014) T. J. Vaughan et al.   Biomechanics and Modeling in Mechanobiology

Osteocytic Canalicular Networks: Morphological Implications for Altered Mechanosensitivity

(2013) Petar Milovanovic et al.   ACS Nano

Fluid flow in the osteocyte mechanical environment: a fluid–structure interaction approach

(2013) Stefaan W. Verbruggen et al.   Biomechanics and Modeling in Mechanobiology

3D osteocyte lacunar morphometric properties and distributions in human femoral cortical bone using synchrotron radiation micro-CT images

(2013) Pei Dong et al.   BONE

Femoral osteocyte lacunar density, volume and morphology in women across the lifespan

(2013) Yasmin Carter et al.   JOURNAL OF STRUCTURAL BIOLOGY

Unique bone histology in partial large bone shafts from Aust Cliff (England, Upper Triassic): an early independent experiment in gigantism

(2012) Ragna Redelstorff   ACTA PALAEONTOLOGICA POLONICA

Interstitial fluid flow within bone canaliculi and electro-chemo-mechanical features of the canalicular milieu

(2012) Vittorio Sansalone et al.   Biomechanics and Modeling in Mechanobiology

Calcium response in osteocytic networks under steady and oscillatory fluid flow

(2012) X. Lucas Lu et al.   BONE

Emerging role of primary cilia as mechanosensors in osteocytes

(2012) An M. Nguyen et al.   BONE

Microscale fluid flow analysis in a human osteocyte canaliculus using a realistic high-resolution image-based three-dimensional model

(2012) Hiroshi Kamioka et al.   Integrative Biology

Advances in assessment of bone porosity, permeability and interstitial fluid flow

(2012) Luis Cardoso et al.   JOURNAL OF BIOMECHANICS

Strain amplification in bone mechanobiology: a computational investigation of the in vivo mechanics of osteocytes

(2012) S. W. Verbruggen et al.   Journal of the Royal Society Interface

On the paradoxical determinations of the lacuno-canalicular permeability of bone

(2011) T. Lemaire et al.   Biomechanics and Modeling in Mechanobiology

Mouse tail vertebrae adapt to cyclic mechanical loading by increasing bone formation rate and decreasing bone resorption rate as shown by time-lapsed in vivo imaging of dynamic bone morphometry

(2011) Floor M. Lambers et al.   BONE

Poorly Ordered Bone as an Endogenous Scaffold for the Deposition of Highly Oriented Lamellar Tissue in Rapidly Growing Ovine Bone

(2011) Michael Kerschnitzki et al.   CELLS TISSUES ORGANS

Direct in vivo strain measurements in human bone—A systematic literature review

(2011) R. Al Nazer et al.   JOURNAL OF BIOMECHANICS

Trabecular bone remodelling simulated by a stochastic exchange of discrete bone packets from the surface

(2011) M.A. Hartmann et al.   Journal of the Mechanical Behavior of Biomedical Materials

Imaging the 3D structure of secondary osteons in human cortical bone using phase-retrieval tomography

(2011) B D Arhatari et al.   PHYSICS IN MEDICINE AND BIOLOGY

Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone

(2010) Björn Busse et al.   AGING CELL

Osteocyte Mechanobiology and Pericellular Mechanics

(2010) Christopher R. Jacobs et al.   Annual Review of Biomedical Engineering

Perlecan/Hspg2 deficiency alters the pericellular space of the lacunocanalicular system surrounding osteocytic processes in cortical bone

(2010) William R Thompson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: Direct evidence for load-induced fluid flow

(2010) Christopher Price et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The amazing osteocyte

(2010) Lynda F Bonewald   JOURNAL OF BONE AND MINERAL RESEARCH

The organization of the osteocyte network mirrors the extracellular matrix orientation in bone

(2010) Michael Kerschnitzki et al.   JOURNAL OF STRUCTURAL BIOLOGY

Poroelastic behaviour of cortical bone under harmonic axial loading: A finite element study at the osteonal scale

(2010) Vu-Hieu Nguyen et al.   MEDICAL ENGINEERING & PHYSICS

Dendritic processes of osteocytes are mechanotransducers that induce the opening of hemichannels

(2010) S. Burra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poroelastic Evaluation of Fluid Movement Through the Lacunocanalicular System

(2009) Grant C. Goulet et al.   ANNALS OF BIOMEDICAL ENGINEERING

Calcium response in single osteocytes to locally applied mechanical stimulus: Differences in cell process and cell body

(2009) Taiji Adachi et al.   JOURNAL OF BIOMECHANICS

Boning up on Wolff's Law: Mechanical regulation of the cells that make and maintain bone

(2009) Jan-Hung Chen et al.   JOURNAL OF BIOMECHANICS

Modeling Fluorescence Recovery After Photobleaching in Loaded Bone: Potential Applications in Measuring Fluid and Solute Transport in the Osteocytic Lacunar-Canalicular System

(2008) Xiaozhou Zhou et al.   ANNALS OF BIOMEDICAL ENGINEERING

Fluid and Solute Transport in Bone: Flow-Induced Mechanotransduction

(2008) Susannah P. Fritton et al.   Annual Review of Fluid Mechanics

Do osteocytes contribute to bone mineral homeostasis? Osteocytic osteolysis revisited

(2008) Anna Teti et al.   BONE