Aging, Osteocytes, and Mechanotransduction

Accuracy and reproducibility of mouse cortical bone microporosity as quantified by desktop microcomputed tomography

(2017) Haniyeh Hemmatian et al.   PLoS One

Osteocyte lacunar properties and cortical microstructure in human iliac crest as a function of age and sex

(2016) Fiona Linnea Bach-Gansmo et al.   BONE

Lactation-Induced Changes in the Volume of Osteocyte Lacunar-Canalicular Space Alter Mechanical Properties in Cortical Bone Tissue

(2016) Serra Kaya et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Multi-level characterization of human femoral cortices and their underlying osteocyte network reveal trends in quality of young, aged, osteoporotic and antiresorptive-treated bone

(2015) Petar Milovanovic et al.   BIOMATERIALS

Novel approaches for two and three dimensional multiplexed imaging of osteocytes

(2015) Suzan A. Kamel-ElSayed et al.   BONE

Quantifying the osteocyte network in the human skeleton

(2015) Pascal R. Buenzli et al.   BONE

Bone cell mechanosensitivity, estrogen deficiency, and osteoporosis

(2015) Jenneke Klein-Nulend et al.   JOURNAL OF BIOMECHANICS

Osteocyte lacunar properties in rat cortical bone: Differences between lamellar and central bone

(2015) Fiona Linnea Bach-Gansmo et al.   JOURNAL OF STRUCTURAL BIOLOGY

3D X-ray ultra-microscopy of bone tissue

(2015) M. Langer et al.   OSTEOPOROSIS INTERNATIONAL

Osteocytic Canalicular Networks: Morphological Implications for Altered Mechanosensitivity

(2013) Petar Milovanovic et al.   ACS Nano

Fluid flow in the osteocyte mechanical environment: a fluid–structure interaction approach

(2013) Stefaan W. Verbruggen et al.   Biomechanics and Modeling in Mechanobiology

Measurement and estimation of osteocyte mechanical strain

(2013) Amber Rath Stern et al.   BONE

Studying osteocytes within their environment

(2013) Duncan J. Webster et al.   BONE

3D osteocyte lacunar morphometric properties and distributions in human femoral cortical bone using synchrotron radiation micro-CT images

(2013) Pei Dong et al.   BONE

The Osteocyte: An Endocrine Cell … and More

(2013) Sarah L. Dallas et al.   ENDOCRINE REVIEWS

Age-related changes in the 3D hierarchical structure of rat tibia cortical bone characterized by high-resolution micro-CT

(2013) John Jast et al.   JOURNAL OF APPLIED PHYSIOLOGY

3D Assessment of Cortical Bone Porosity and Tissue Mineral Density Using High-Resolution µCT: Effects of Resolution and Threshold Method

(2013) Paolo E Palacio-Mancheno et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Femoral osteocyte lacunar density, volume and morphology in women across the lifespan

(2013) Yasmin Carter et al.   JOURNAL OF STRUCTURAL BIOLOGY

Age- and Menopause-Related Bone Loss Compromise Cortical and Trabecular Microstructure

(2013) E. Seeman   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Osteoporosis in the European Union: medical management, epidemiology and economic burden

(2013) E. Hernlund et al.   Archives of Osteoporosis

Prolonged unloading in growing rats reduces cortical osteocyte lacunar density and volume in the distal tibia

(2012) Hayley M. Britz et al.   BONE

The early mouse 3D osteocyte network in the presence and absence of mechanical loading

(2012) Yasuyo Sugawara et al.   BONE

Mechanosensation and transduction in osteocytes

(2012) Jenneke Klein-Nulend et al.   BONE

Variation in osteocyte lacunar morphology and density in the human femur — a synchrotron radiation micro-CT study

(2012) Yasmin Carter et al.   BONE

The importance of the intracortical canal network for murine bone mechanics

(2012) Philipp Schneider et al.   BONE

IMAGE-BASED FINITE ELEMENT MODELS FOR THE INVESTIGATION OF OSTEOCYTE MECHANOTRANSDUCTION

(2012) Philipp Schneider et al.   JOURNAL OF BIOMECHANICS

Advances in assessment of bone porosity, permeability and interstitial fluid flow

(2012) Luis Cardoso et al.   JOURNAL OF BIOMECHANICS

Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation

(2012) Hai Qing et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Serial FIB/SEM imaging for quantitative 3D assessment of the osteocyte lacuno-canalicular network

(2011) Philipp Schneider et al.   BONE

The importance of murine cortical bone microstructure for microcrack initiation and propagation

(2011) R. Voide et al.   BONE

The Three-Dimensional Morphometry and Cell–Cell Communication of the Osteocyte Network in Chick and Mouse Embryonic Calvaria

(2011) Yasuyo Sugawara et al.   CALCIFIED TISSUE INTERNATIONAL

Matrix-embedded cells control osteoclast formation

(2011) Jinhu Xiong et al.   NATURE MEDICINE

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

(2011) Tomoki Nakashima et al.   NATURE MEDICINE

Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone

(2010) Björn Busse et al.   AGING CELL

Effects of cyclic hydraulic pressure on osteocytes

(2010) Chao Liu et al.   BONE

Towards quantitative 3D imaging of the osteocyte lacuno-canalicular network

(2010) Philipp Schneider et al.   BONE

Bimodal distribution of osteocyte lacunar size in the human femoral cortex as revealed by micro-CT

(2010) K.M. Hannah et al.   BONE

Inhibition of Osteoclastogenesis by Mechanically Loaded Osteocytes: Involvement of MEPE

(2010) Rishikesh N. Kulkarni et al.   CALCIFIED TISSUE INTERNATIONAL

β1 Integrins Mediate Mechanosensitive Signaling Pathways in Osteocytes

(2010) Julie B. Litzenberger et al.   CALCIFIED TISSUE INTERNATIONAL

Cellular responses to mechanical loading in vitro

(2010) Alicia J. El Haj et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Real-time measurement of solute transport within the lacunar-canalicular system of mechanically loaded bone: Direct evidence for load-induced fluid flow

(2010) Christopher Price et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Structure and remodelling of the human parietal bone: An age and gender histomorphometric study

(2010) Daniel Torres-Lagares et al.   JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY

Ptychographic X-ray computed tomography at the nanoscale

(2010) Martin Dierolf et al.   NATURE

Attachment of Osteocyte Cell Processes to the Bone Matrix

(2009) L.M. McNamara et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Early activation of the β-catenin pathway in osteocytes is mediated by nitric oxide, phosphatidyl inositol-3 kinase/Akt, and focal adhesion kinase

(2009) Ana Santos et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Osteocyte morphology in human tibiae of different bone pathologies with different bone mineral density — Is there a role for mechanosensing?

(2009) Ruud P. van Hove et al.   BONE

Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes

(2009) Ana Santos et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Methodological assessment of acid-etching for visualizing the osteocyte lacunar-canalicular networks using scanning electron microscopy

(2009) Daniel J. Kubek et al.   MICROSCOPY RESEARCH AND TECHNIQUE

Hierarchical microimaging of bone structure and function

(2009) Ralph Müller   Nature Reviews Rheumatology

Fluid and Solute Transport in Bone: Flow-Induced Mechanotransduction

(2008) Susannah P. Fritton et al.   Annual Review of Fluid Mechanics

Paxillin localisation in osteocytes—Is it determined by the direction of loading?

(2008) A. Vatsa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Osteocyte morphology in fibula and calvaria — Is there a role for mechanosensing?

(2008) Aviral Vatsa et al.   BONE

The alteration of a mechanical property of bone cells during the process of changing from osteoblasts to osteocytes

(2008) Yasuyo Sugawara et al.   BONE

Round versus flat: Bone cell morphology, elasticity, and mechanosensing

(2008) Rommel G. Bacabac et al.   JOURNAL OF BIOMECHANICS

Quantitative associations between osteocyte density and biomechanics, microcrack and microstructure in OVX rats vertebral trabeculae

(2008) Yu-Lin Ma et al.   JOURNAL OF BIOMECHANICS

Idealization of pericellular fluid space geometry and dimension results in a profound underprediction of nano-microscale stresses imparted by fluid drag on osteocytes

(2008) Eric J. Anderson et al.   JOURNAL OF BIOMECHANICS

Osteocytes as mechanosensors in the inhibition of bone resorption due to mechanical loading

(2007) Lidan You et al.   BONE