Mechanism of sphingosine 1-phosphate clearance from blood

Saccharomyces cerevisiae as a platform for assessing sphingolipid lipid kinase inhibitors

(2018) Yugesh Kharel et al.   PLoS One

The phosphatidic acid–binding, polybasic domain is responsible for the differences in the phosphoregulation of lipins 1 and 3

(2017) Salome Boroda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets

(2017) Thiet M. Vu et al.   NATURE

Tetracyclines increase lipid phosphate phosphatase expression on plasma membranes and turnover of plasma lysophosphatidate

(2016) Xiaoyun Tang et al.   JOURNAL OF LIPID RESEARCH

Sphingosine-1-phosphate promotes erythrocyte glycolysis and oxygen release for adaptation to high-altitude hypoxia

(2016) Kaiqi Sun et al.   Nature Communications

Quantification of sphingosine 1-phosphate by validated LC-MS/MS method revealing strong correlation with apolipoprotein M in plasma but not in serum due to platelet activation during blood coagulation

(2015) Cecilia Frej et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Lipid phosphate phosphatases and their roles in mammalian physiology and pathology

(2015) Xiaoyun Tang et al.   JOURNAL OF LIPID RESEARCH

Structure−Activity Relationship Studies and in Vivo Activity of Guanidine-Based Sphingosine Kinase Inhibitors: Discovery of SphK1- and SphK2-Selective Inhibitors

(2015) Neeraj N. Patwardhan et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mice With Targeted Inactivation of Ppap2b in Endothelial and Hematopoietic Cells Display Enhanced Vascular Inflammation and Permeability

(2014) Manikandan Panchatcharam et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Characterization of Human Antiviral Adaptive Immune Responses during Hepatotropic Virus Infection in HLA-Transgenic Human Immune System Mice

(2013) E. Billerbeck et al.   JOURNAL OF IMMUNOLOGY

Mechanism of rapid elimination of lysophosphatidic acid and related lipids from the circulation of mice

(2013) Abdel K. Salous et al.   JOURNAL OF LIPID RESEARCH

Simultaneous quantitation of sphingoid bases and their phosphates in biological samples by liquid chromatography/electrospray ionization tandem mass spectrometry

(2012) Daisuke Saigusa et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Sphingosine kinase type 2 inhibition elevates circulating sphingosine 1-phosphate

(2012) Yugesh Kharel et al.   BIOCHEMICAL JOURNAL

Sphingosine kinase type 1 inhibition reveals rapid turnover of circulating sphingosine 1-phosphate

(2011) Yugesh Kharel et al.   BIOCHEMICAL JOURNAL

Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development

(2011) Alejandro López-Juárez et al.   GLIA

Lipid phosphate phosphatase 3 enables efficient thymic egress

(2011) Béatrice Bréart et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sphingosine 1-Phosphate Lyase Deficiency Disrupts Lipid Homeostasis in Liver

(2010) Meryem Bektas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Erythrocytes serve as a reservoir for cellular and extracellular sphingosine 1-phosphate

(2010) Constantin Bode et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Redistribution of Sphingosine 1-Phosphate by Sphingosine Kinase 2 Contributes to Lymphopenia

(2010) S. C. Sensken et al.   JOURNAL OF IMMUNOLOGY

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

FTY720 (fingolimod) in Multiple Sclerosis: therapeutic effects in the immune and the central nervous system

(2009) Volker Brinkmann   BRITISH JOURNAL OF PHARMACOLOGY

Sphingosine-1-phosphate in the plasma compartment regulates basal and inflammation-induced vascular leak in mice

(2009) Eric Camerer et al.   JOURNAL OF CLINICAL INVESTIGATION

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake

(2008) Ulrike Peest et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Quantitative analysis of sphingolipids for lipidomics using triple quadrupole and quadrupole linear ion trap mass spectrometers

(2008) Rebecca L. Shaner et al.   JOURNAL OF LIPID RESEARCH