The protective role of autophagy in experimental osteoarthritis, and the therapeutic effects of Torin 1 on osteoarthritis by activating autophagy

Shiga toxins induce autophagic cell death in intestinal epithelial cells via the endoplasmic reticulum stress pathway

(2015) Bin Tang et al.   Autophagy

A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90

(2015) Christopher NJ Young et al.   Autophagy

­­­­­Insulin-Like Growth Factor II (IGF-II) Inhibits IL-1β-Induced Cartilage Matrix Loss and Promotes Cartilage Integrity in Experimental Osteoarthritis

(2015) Tomoya Uchimura et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Injury of primary afferent neurons may contribute to osteoarthritis induced pain: an experimental study using the collagenase model in rats

(2015) S. Adães et al.   OSTEOARTHRITIS AND CARTILAGE

Mitochondrial Membrane Potential and Nuclear and Gene Expression Changes During Human Disc Cell Apoptosis

(2015) Helen E. Gruber et al.   SPINE

Defective autophagy in chondrocytes with Kashin-Beck disease but higher than osteoarthritis

(2014) C. Wu et al.   OSTEOARTHRITIS AND CARTILAGE

Intra-articular injection of collagenase in the knee of rats as an alternative model to study nociception associated with osteoarthritis

(2014) Sara Adães et al.   ARTHRITIS RESEARCH & THERAPY

Enhancement of chondrocyte autophagy is an early response in the degenerative cartilage of the temporomandibular joint to biomechanical dental stimulation

(2013) Mian Zhang et al.   APOPTOSIS

Osteoarthritis — A Silent Problem that Needs Our Attention!

(2013) Thomas M. Best et al.   Current Sports Medicine Reports

Autophagy Prior to Chondrocyte Cell Death During the Degeneration of Meckel's Cartilage

(2012) Rong-Tao Yang et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Autophagic proteins

(2012) Yang Jin et al.   Autophagy

Trapeziectomy and tendon suspension with or without a Mitek anchor fixation in the thumb basal joint osteoarthritis

(2012) S. Nordback et al.   Journal of Hand Surgery-European Volume

Autophagy: A New Therapeutic Target in Cartilage Injury and Osteoarthritis

(2012) Martin Lotz et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Repeated measurements, bilateral observations and pseudoreplicates, why does it matter?

(2012) J. Ranstam   OSTEOARTHRITIS AND CARTILAGE

Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF

(2012) Stefanie Haas et al.   ARTHRITIS RESEARCH & THERAPY

Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage

(2012) Valeria M Dejica et al.   ARTHRITIS RESEARCH & THERAPY

TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro

(2012) Jun Qin et al.   ARTHRITIS RESEARCH & THERAPY

Autophagy activation by rapamycin reduces severity of experimental osteoarthritis

(2011) Beatriz Caramés et al.   ANNALS OF THE RHEUMATIC DISEASES

Chasing the elusive mammalian microautophagy

(2011) Laura Santambrogio et al.   Autophagy

Autophagy-Is it a preferred route for lifespan extension?

(2011) Meenakshi Dwivedi et al.   BMB Reports

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Chaperone-mediated autophagy at a glance

(2011) S. Kaushik et al.   JOURNAL OF CELL SCIENCE

Cell death of chondrocytes is a combination between apoptosis and autophagy during the pathogenesis of Osteoarthritis within an experimental model

(2010) M. Almonte-Becerril et al.   APOPTOSIS

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

(2010) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

c-Jun N-terminal kinase and nuclear factor κB mediate nitric oxide-induced expression of matrix metalloproteinase-13

(2010) Lin Yang et al.   INTERNATIONAL ORTHOPAEDICS

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting cartilage erosion in OA

(2010) Jenny Buckland   Nature Reviews Rheumatology

Analysis of early changes in the articular cartilage transcriptisome in the rat meniscal tear model of osteoarthritis: pathway comparisons with the rat anterior cruciate transection model and with human osteoarthritic cartilage

(2010) T. Wei et al.   OSTEOARTHRITIS AND CARTILAGE

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Physiological role of autophagy as an intracellular recycling system: With an emphasis on nutrient metabolism

(2010) Akiko Kuma et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MT3-MMP (MMP-16) is Downregulated byIn VitroCytokine Stimulation of Cartilage, but Unaltered in Naturally Occurring Equine Osteoarthritis and Osteochondrosis

(2008) E. R. Garvican et al.   CONNECTIVE TISSUE RESEARCH

Role of proinflammatory cytokines in cisplatin-induced vestibular hair cell damage

(2008) Hyung-Jin Kim et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Autophagy and aging: keeping that old broom working

(2008) Ana Maria Cuervo   TRENDS IN GENETICS