The role of the key autophagy kinase ULK1 in hepatocellular carcinoma and its validation as a treatment target

Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma

(2019) Xiu-Tao Fu et al.   Cancer Cell International

Combination of ULK1 and LC3B improve prognosis assessment of hepatocellular carcinoma

(2018) Dong-hao Wu et al.   BIOMEDICINE & PHARMACOTHERAPY

CD24 regulates sorafenib resistance via activating autophagy in hepatocellular carcinoma

(2018) Shuai Lu et al.   Cell Death & Disease

Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo

(2017) Lan Zhang et al.   Chemical Science

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

AMPK–ULK1-Mediated Autophagy Confers Resistance to BET Inhibitor JQ1 in Acute Myeloid Leukemia Stem Cells

(2016) Ji Eun Jang et al.   CLINICAL CANCER RESEARCH

Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors

(2015) Michael B. Lazarus et al.   ACS Chemical Biology

PSMD10/gankyrin induces autophagy to promote tumor progression through cytoplasmic interaction with ATG7 and nuclear transactivation of ATG7 expression

(2015) Tao Luo et al.   Autophagy

Pharmacological Inhibition of ULK1 Kinase Blocks Mammalian Target of Rapamycin (mTOR)-dependent Autophagy

(2015) Katy J. Petherick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy in cellular metabolism and cancer

(2015) Xuejun Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

(2015) Daniel F. Egan et al.   MOLECULAR CELL

Inhibition of Akt Reverses the Acquired Resistance to Sorafenib by Switching Protective Autophagy to Autophagic Cell Death in Hepatocellular Carcinoma

(2014) B. Zhai et al.   MOLECULAR CANCER THERAPEUTICS

Autophagy: A novel therapeutic target for hepatocarcinoma (Review)

(2014) ZHANGGUI WANG et al.   Oncology Letters

TRIB2 Acts Downstream of Wnt/TCF in Liver Cancer Cells to Regulate YAP and C/EBPα Function

(2013) Jiayi Wang et al.   MOLECULAR CELL

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Sorafenib in treatment of patients with advanced hepatocellular carcinoma: a systematic review

(2012) Xin Zhang et al.   Hepatobiliary & Pancreatic Diseases International

Hepatocellular carcinoma

(2012) Alejandro Forner et al.   LANCET

Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis

(2011) Ying-Hong Shi et al.   Autophagy

A General Framework for Inhibitor Resistance in Protein Kinases

(2011) Deborah Balzano et al.   CHEMISTRY & BIOLOGY

Inhibition of autophagy potentiates the antitumor effect of the multikinase inhibitor sorafenib in hepatocellular carcinoma

(2011) Satoshi Shimizu et al.   INTERNATIONAL JOURNAL OF CANCER

MicroRNA-30a Sensitizes Tumor Cells to cis-Platinum via Suppressing Beclin 1-mediated Autophagy

(2011) Zhenyou Zou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

A novel quantitative flow cytometry-based assay for autophagy

(2010) Kai Er Eng et al.   Autophagy

Hepatocellular carcinoma: a global view

(2010) Ju Dong Yang et al.   Nature Reviews Gastroenterology & Hepatology

Liver Transplantation

(2009) Deok-Bog Moon et al.   Gut and Liver

Surgery for malignant liver tumors

(2009) ParulJ Shukla et al.   Journal of Cancer Research and Therapeutics