A potential role for protein palmitoylation and zDHHC16 in DNA damage response

Mechanisms of ATM Activation

(2015) Tanya T. Paull   Annual Review of Biochemistry

Deciphering the DNA Damage Response

(2015) James E. Haber   CELL

DNA damage foci: Meaning and significance

(2015) Kai Rothkamm et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The DNA Damage Response—Self-awareness for DNA

(2015) Stephen J. Elledge   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Oncolytic reovirus induces intracellular redistribution of Ras to promote apoptosis and progeny virus release

(2015) K A Garant et al.   ONCOGENE

p53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers

(2015) Xinsen Ruan et al.   Journal of Molecular Cell Biology

Mechanistic effects of protein palmitoylation and the cellular consequences thereof

(2014) Sanja Blaskovic et al.   CHEMISTRY AND PHYSICS OF LIPIDS

2-Bromopalmitate modulates neuronal differentiation through the regulation of histone acetylation

(2014) Xueran Chen et al.   Stem Cell Research

Profiling Targets of the Irreversible Palmitoylation Inhibitor 2-Bromopalmitate

(2013) Dahvid Davda et al.   ACS Chemical Biology

Local palmitoylation cycles define activity-regulated postsynaptic subdomains

(2013) Yuko Fukata et al.   JOURNAL OF CELL BIOLOGY

2-Bromopalmitate Analogues as Activity-Based Probes To Explore Palmitoyl Acyltransferases

(2013) Baohui Zheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Histone H4 deacetylation facilitates 53BP1 DNA damage signaling and double-strand break repair

(2013) K.-Y. Hsiao et al.   Journal of Molecular Cell Biology

 -H2AX Foci Formation as a Pharmacodynamic Marker of DNA Damage Produced by DNA Cross-Linking Agents: Results from 2 Phase I Clinical Trials of SJG-136 (SG2000)

(2012) J. Wu et al.   CLINICAL CANCER RESEARCH

A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response

(2012) Jenny Fung Ling Chau et al.   Nature Communications

DNA damage response: The emerging role of c-Abl as a regulatory switch?

(2011) Emiliano Maiani et al.   BIOCHEMICAL PHARMACOLOGY

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Human DHHC proteins: A spotlight on the hidden player of palmitoylation

(2011) Justyna Korycka et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Global profiling of dynamic protein palmitoylation

(2011) Brent R Martin et al.   NATURE METHODS

The Role of Palmitoylation in Signalling, Cellular Trafficking and Plasma Membrane Localization of Protease-Activated Receptor-2

(2011) Mark N. Adams et al.   PLoS One

DHHC palmitoyl transferases: substrate interactions and (patho)physiology

(2011) Jennifer Greaves et al.   TRENDS IN BIOCHEMICAL SCIENCES

c-Abl tyrosine kinase in the DNA damage response: cell death and more

(2010) V Meltser et al.   CELL DEATH AND DIFFERENTIATION

A positive role for c-Abl in Atm and Atr activation in DNA damage response

(2010) X Wang et al.   CELL DEATH AND DIFFERENTIATION

Mice with Alopecia, Osteoporosis, and Systemic Amyloidosis Due to Mutation in Zdhhc13, a Gene Coding for Palmitoyl Acyltransferase

(2010) Amir N. Saleem et al.   PLoS Genetics

Doxorubicin: The Good, the Bad and the Ugly Effect

(2009) Cristina Carvalho et al.   CURRENT MEDICINAL CHEMISTRY

Proteome Scale Characterization of HumanS-Acylated Proteins in Lipid Raft-enriched and Non-raft Membranes

(2009) Wei Yang et al.   MOLECULAR & CELLULAR PROTEOMICS

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Protein Palmitoylation Regulates Osteoblast Differentiation through BMP-Induced Osterix Expression

(2009) Wai Fook Leong et al.   PLoS One

Palmitoylation Regulates Epidermal Homeostasis and Hair Follicle Differentiation

(2009) Pleasantine Mill et al.   PLoS Genetics

2-Bromopalmitate and 2-(2-hydroxy-5-nitro-benzylidene)-benzo[b]thiophen-3-one inhibit DHHC-mediated palmitoylation in vitro

(2008) Benjamin C. Jennings et al.   JOURNAL OF LIPID RESEARCH