Functional Characterization of LIPA (Lysosomal Acid Lipase) Variants Associated With Coronary Artery Disease

LAL (Lysosomal Acid Lipase) Promotes Reverse Cholesterol Transport In Vitro and In VivoHighlights

(2018) Kristin L. Bowden et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis

(2018) Li-Hao Huang et al.   Cell Metabolism

Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens

(2016) Yohann Nédélec et al.   CELL

Degradation of aggregated LDL occurs in complex extracellular sub-compartments of the lysosomal synapse

(2016) Rajesh K. Singh et al.   JOURNAL OF CELL SCIENCE

Prediction of Causal Candidate Genes in Coronary Artery Disease LociSignificance

(2015) Ingrid Brænne et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Degradation and beyond

(2015) Ismail Sergin et al.   CURRENT OPINION IN LIPIDOLOGY

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

Induction of Lysosomal Biogenesis in Atherosclerotic Macrophages Can Rescue Lipid-Induced Lysosomal Dysfunction and Downstream Sequelae

(2014) Roy Emanuel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Exome Sequencing and Directed Clinical Phenotyping Diagnose Cholesterol Ester Storage Disease Presenting as Autosomal Recessive Hypercholesterolemia

(2013) Nathan O. Stitziel et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice

(2013) Catherine Martel et al.   JOURNAL OF CLINICAL INVESTIGATION

Cholesteryl ester storage disease: Review of the findings in 135 reported patients with an underdiagnosed disease

(2013) Donna L. Bernstein et al.   JOURNAL OF HEPATOLOGY

Single Nucleotide Polymorphisms within LIPA (Lysosomal Acid Lipase A) Gene Are Associated with Susceptibility to Premature Coronary Artery Disease. A Replication in the Genetic of Atherosclerotic Disease (GEA) Mexican Study

(2013) Gilberto Vargas-Alarcón et al.   PLoS One

A new method for the measurement of lysosomal acid lipase in dried blood spots using the inhibitor Lalistat 2

(2012) John Hamilton et al.   CLINICA CHIMICA ACTA

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

A Genome-Wide Association Study Identifies LIPA as a Susceptibility Gene for Coronary Artery Disease

(2011) Philipp S. Wild et al.   Circulation-Cardiovascular Genetics

Wolman Disease (LIPA p.G87V) Genotype Frequency in People of Iranian-Jewish Ancestry

(2011) Yadira Valles-Ayoub et al.   Genetic Testing and Molecular Biomarkers

Lysosomal Acid Lipase Deficiency Impairs Regulation ofABCA1Gene and Formation of High Density Lipoproteins in Cholesteryl Ester Storage Disease

(2011) Kristin L. Bowden et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A sensitive assay for ABCA1-mediated cholesterol efflux using BODIPY-cholesterol

(2011) Sandhya Sankaranarayanan et al.   JOURNAL OF LIPID RESEARCH

A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease

(2011) John F Peden et al.   NATURE GENETICS

Short Report on DNA Marker at Candidate Locus

(2010) H. Wiebusch et al.   CLINICAL GENETICS

A simple and sensitive enzymatic method for cholesterol quantification in macrophages and foam cells

(2010) Peggy Robinet et al.   JOURNAL OF LIPID RESEARCH

Sorting of lysosomal proteins

(2008) Thomas Braulke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH