Comparative Evaluation of the In Vitro Activities of WCK 5222 (Cefepime-Zidebactam) and Combination Antibiotic Therapies against Carbapenem-Resistant Pseudomonas aeruginosa

The clinical relevance of in vitro synergistic activity of antibiotics for MDR Gram-negative infections: A systematic review

(2019) Konstantinos Z. Vardakas et al.   Journal of Global Antimicrobial Resistance

A Combination Antibiogram Evaluation for Pseudomonas aeruginosa in Respiratory and Blood Sources from Intensive Care Unit (ICU) and Non-ICU Settings in U.S. Hospitals

(2019) Laura Puzniak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) against Multidrug-Resistant Pseudomonas aeruginosa in the Neutropenic Murine Thigh Infection Model

(2019) Marguerite L. Monogue et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Combination of MexAB-OprM overexpression and mutations in efflux regulators, PBPs and chaperone proteins is responsible for ceftazidime/avibactam resistance in Pseudomonas aeruginosa clinical isolates from US hospitals

(2019) Mariana Castanheira et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Single β-lactams versus combinations as empiric therapy for infections with Pseudomonas aeruginosa: assessing the in vitro susceptibility

(2019) Safa S. Almarzoky Abuhussain et al.   Infectious Diseases

Feasibility of routine synergy testing using antibiotic gradient diffusion strips in the clinical laboratory

(2018) Lindsay M Avery et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234

(2018) Krisztina M. Papp-Wallace et al.   JOURNAL OF MEDICINAL CHEMISTRY

OUP accepted manuscript

(2018)   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

WCK 5222 (cefepime/zidebactam) antimicrobial activity tested against Gram-negative organisms producing clinically relevant β-lactamases

(2017) Helio S. Sader et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Potency of parenteral antimicrobials including ceftolozane/tazobactam against nosocomial respiratory tract pathogens: considerations for empiric and directed therapy

(2017) Christina A. Sutherland et al.   Journal of Thoracic Disease

Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

(2016) Andre C. Kalil et al.   CLINICAL INFECTIOUS DISEASES

Is double coverage of gram-negative organisms necessary?

(2011) S. J. Johnson et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY