In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) against Multidrug-Resistant Pseudomonas aeruginosa in the Neutropenic Murine Thigh Infection Model

Plasma and Intrapulmonary Concentrations of Cefepime and Zidebactam following Intravenous Administration of WCK 5222 to Healthy Adult Subjects

(2018) Keith A. Rodvold et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Strategic Approaches to Overcome Resistance against Gram-Negative Pathogens Using β-Lactamase Inhibitors and β-Lactam Enhancers: Activity of Three Novel Diazabicyclooctanes WCK 5153, Zidebactam (WCK 5107), and WCK 4234

(2018) Krisztina M. Papp-Wallace et al.   JOURNAL OF MEDICINAL CHEMISTRY

Assessment of the In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) Against Carbapenem-Resistant Acinetobacter baumannii in the Neutropenic Murine Lung Infection Model

(2018) Lindsay M. Avery et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In Vivo Efficacy of Humanized WCK 5222 (Cefepime-Zidebactam) Exposures against Carbapenem-Resistant Acinetobacter baumannii in the Neutropenic Thigh Model

(2018) Safa S. Almarzoky Abuhussain et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

WCK 5222 (cefepime/zidebactam) antimicrobial activity tested against Gram-negative organisms producing clinically relevant β-lactamases

(2017) Helio S. Sader et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Antimicrobial-Resistant Pathogens Associated With Healthcare-Associated Infections: Summary of Data Reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2011–2014

(2016) Lindsey M. Weiner et al.   INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY

Human Simulated Studies of Aztreonam and Aztreonam-Avibactam To Evaluate Activity against Challenging Gram-Negative Organisms, Including Metallo-β-Lactamase Producers

(2013) Jared L. Crandon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Impact of multidrug-resistantPseudomonas aeruginosainfection on patient outcomes

(2010) Elizabeth B Hirsch et al.   Expert Review of Pharmacoeconomics & Outcomes Research