Article
Engineering, Environmental
Wenxing Gao, Qiang Li, Qi- Long Yan, Wencheng Zhong, Xiaomeng Zhou, Li Shang
Summary: The development of reliable sensors for explosive detection is crucial for reducing safety risks and environmental concerns. However, achieving on-site detection of multiple analytes in a simple and efficient way remains highly challenging.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Food Science & Technology
Hong-Xin Ren, Min-Xin Mao, Min Li, Cun-Zheng Zhang, Chi-Fang Peng, Jiang-Guo Xu, Xin-Lin Wei
Summary: This report proposed a fluorescent sensing method for paraquat based on gold nanoclusters. The modification of beta-cyclodextrins on the surface of AuNCs enhanced the sensitivity and selectivity of the detection. With optimized conditions, the method demonstrated a linear response and high recoveries when applied to paraquat-spiked water samples. This study highlights the potential of host molecule modification of fluorescent metal NC surfaces in developing robust sensors.
Article
Chemistry, Applied
Yongqiang Shi, Wenting Li, Xuping Feng, Lei Lin, Pengcheng Nie, Jiyong Shi, Xiaobo Zou, Yong He
Summary: A novel aptamer-modified Copper @ Gold nanoclusters based ratiometric fluorescent probe was developed for mercury ions determination in Porphyra, with a detection limit of 4.92 nM. Additionally, a homemade device for colorimetric determination of Hg2+ was designed, showing good portability and usefulness. The study suggests the considerable potential of these methods for evaluating Hg2+ levels in aquatic products.
Article
Chemistry, Multidisciplinary
Wencheng Zhong, Kangqiang Liang, Wenfeng Liu, Li Shang
Summary: In this study, a new design of Forster resonance energy transfer-based dual-color photoswitchable fluorescent nanoparticles (DPF NPs) was reported by using ligand-protected gold nanoclusters (AuNCs). The ultrasmall-sized AuNCs act as the FRET donors and also regulate the properties of spiropyran through ligand-spiropyran interactions. These DPF NPs exhibit high fluorescence on/off ratios for both green and red fluorescence emission, and show good reversibility during cycled photo-stimulation. Cell imaging experiments demonstrated that DPF NPs can specifically accumulate in lipid droplets and enable photoswitchable dual-color imaging in living cells.
Article
Engineering, Environmental
Pengjuan Ni, Siyuan Liu, Bo Wang, Chuanxia Chen, Yuanyuan Jiang, Chenghui Zhang, Jianbin Chen, Yizhong Lu
Summary: A fluorescent assay for total antioxidant capacity detection has been developed using the light-responsive oxidase-like activity of BSA-AuNCs. This method enables the rapid oxidation of TH under neutral conditions and has been successfully utilized for detecting antioxidants and vitamin C tablets.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Chemistry, Analytical
Bo Fu, Xinyu Zheng, Huihui Li, Lu Ding, Fuxiang Wang, Dong-Yu Guo, Weiting Yang, Qinhe Pan
Summary: This study developed a fluorescent probe for highly stable, rapid, and sensitive determination of CIP through Al3+-enhanced fluorescence of gold nanoclusters, exhibiting ratiometric response and the ability to avoid analyte-independent interference.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Applied
Feiyan Liu, Xuandi Lai, Shengliang Zhao, Zhiyang Lu, Peigang Han, Liqiong Chen
Summary: A simple and rapid fluorescent method based on gold nanoclusters (AuNCs) was developed for the determination of Cr6+. The method exhibited good sensitivity and selectivity, and showed favorable recovery and accuracy in actual samples.
Article
Chemistry, Analytical
Mengke Wang, Yaqing Han, Rui Huang, Zhonghao Wang, Guannan Wang
Summary: The confinement effect of AuNCs@HDS significantly improves the fluorescence properties of AuNCs and enables versatile fluorescent sensing strategy for bio-enzymes.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Applied
Yahui Guo, Helena T. N. N. Amunyela, Yuliang Cheng, Yunfei Xie, Hang Yu, Weirong Yao, Hung-Wing Li, He Qian
Summary: Metal nanoclusters, especially protein-templated gold nanoclusters, have attracted significant interest for their unique properties and potential applications. Natural proteins serve as ideal templates for the synthesis of these nanoclusters, allowing for exploration of their properties and applications in various fields.
Article
Materials Science, Multidisciplinary
Liyun Yang, Yuanping Liao, Zhiqiang Zhou
Summary: In this study, a fluorescent probe for detecting glutathione (GSH) was developed by capping 11-mercaptoundecanoic acid (11-MUA) on gold nanoclusters (AuNCs) and combining them with copper ions (Cu2+). The fluorescence of AuNCs was quenched in the presence of Cu2+, and the addition of GSH resulted in the detachment of Cu2+ and fluorescence recovery. The detection range of GSH was 0.05-5 μM with a detection limit of 33.3 nM. The proposed sensor showed potential applicability for accurate GSH detection in commercial drugs and cell lysate.
Review
Chemistry, Applied
Huang Shuai, Cheng Xiang, Lei Qian, Feng Bin, Liu Xiaohui, Ding Jipeng, Zhong Chang, Liang Jiahui, Zeng Wenbin
Summary: The study summarizes recent efforts in developing fluorescent probes for detecting mercury ions, highlighting strategies, methods, and capabilities of the probes, as well as proposing prospects for future research.
Article
Chemistry, Analytical
Hong-Xin Ren, Zhi-Juan Qian, Min Li, Chi-Fang Peng, Zhou-Ping Wang, Xin-Lin Wei, Jian-Guo Xu
Summary: By preparing a core-shell QDs@mSiO(2)@y-AuNCs nanoprobe, a new ratiometric fluorescent sensor for thiram detection was successfully developed. The mechanism of thiram sensing was attributed to the formation of Au-S bonds between thiram and Au atoms on y-AuNCs surface, leading to the dissociation of 11-MUA ligand from the y-AuNCs surface and the charge transfer between thiram and y-AuNCs. The ratiometric fluorescence detection of thiram based on QDs@mSiO(2)@y-AuNCs showed a 3-fold enhanced sensitivity compared to fluorescence detection based on y-AuNCs, with a linear range of 0.5-60 ng/mL and a LOD of 0.19 ng/mL.
Article
Chemistry, Analytical
Xue Zou, Jie Hu, Huanhuan Zhu, Qiumeng Chen, Zhengjun Gong
Summary: A novel fluorescence turn-off sensing strategy was developed for I- ions detection using CDs/His-AuNCs hybrid probes. The fluorescence of the probes was effectively turned off by I- ions through internal filtration effect. Quantitative analysis of I- ions can be achieved by analyzing the fluorescence quenching degree. The established sensing platform has been successfully applied for the detection of I- ions in practical water samples. This work provides new insight into the determination of anions using fluorescent nanoparticles.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Physical
Gyongyi Gombar, Peter Simon, Ditta Ungor, Istvan Szatmari, Edit Csapo
Summary: A new biomolecule, HisHA, is demonstrated to produce few-atomic fluorescent gold nanoclusters (Au NCs) in water. The preparation protocol is optimized by studying various factors, and the role of citrate as a reducing agent is explored. The stability of these NCs under high salt concentration and their ability to detect metal ions (copper and zinc) is confirmed.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Physical
Jun Zhang, Ruchun Chen, Qizhen Chen, Yongmei Hu, Shuang Pan, Xiaoli Hu
Summary: This work presents an ascorbic acid sensing platform using MnO2 nanosheets and gold nanocluster as a ratiometric fluorescent probe, achieving a sensitive method for AA detection with a low limit of detection.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Nanoscience & Nanotechnology
Jie Feng, Wen-Xiu Ren, Jia-Lin Gao, Fei Li, Fei Kong, Bing-Jian Yao, Yu-Bin Dong
Summary: The study introduced a COF-based nanocomposite Fe3O4@COF-DhaTph as a multifunctional nanoagent for cancer theranostics under single 660 nm NIR irradiation. Apart from photothermal and photodynamic effects, this nanoagent also allows triple-modal magnetic resonance/photoacoustic/near-infrared thermal imaging, potentially advancing the application of COF-based multifunctional nanomaterials in cancer theranostics.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Qing Wang, Kaiyue Tan, Hong Wang, Jinhua Shang, Yeqing Wan, Xiaoqing Liu, Xiaocheng Weng, Fuan Wang
Summary: The study introduces an epigenetically responsive DNAzyme system that can be specifically activated by FTO demethylation for precise intracellular imaging-directed gene regulation, offering a versatile toolbox for programmable gene regulation in synthetic biology.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Nanoscience & Nanotechnology
Tianhui Shi, Jialing Hu, Wenxiao Wang, Qunying Jiang, Zhen Xu, Shuyi Yu, Fuan Wang, Xiaoqing Liu
Summary: A Met-targeted nanoinhibitor was developed to efficiently suppress metastasis by multiple blockading HGF/Met signaling pathway. This method showed remarkable inhibition of tumor metastasis in an orthotopic breast tumor model.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Chemistry, Multidisciplinary
Zhen Xu, Li Zhang, Min Pan, Qunying Jiang, Yunjie Huang, Fuan Wang, Xiaoqing Liu
Summary: Nanozymes have great potential in nanomedicine, but their clinical translation is limited by biotoxicity. A new type of bionanozyme with ultrahigh and light-controlled catalytic activity has been developed through self-assembly and in situ polymerization, showing potential for tumor-specific therapy with minimal biotoxicity.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Analytical
Yeqing Wan, Gaiping Li, Lina Zou, Hong Wang, Qing Wang, Kaiyue Tan, Xiaoqing Liu, Fuan Wang
Summary: A self-catalytic DNA assembly (SDA) machine was developed for programmable assembly of functional DNA nanostructures in living cells, enabling sensitive detection of cancer biomarkers such as miR-21. The system combines catalytic self-assembly (CSA) and DNAzyme amplification modules to achieve a self-catalytic amplification reaction, leading to precise intracellular imaging and potential for early cancer diagnosis.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
Shuang Li, Qunying Jiang, Yahua Liu, Wenxiao Wang, Wenqian Yu, Fuan Wang, Xiaoqing Liu
Summary: Accurate diagnosis and targeted therapy are important for precision theranostics. This study presents an activatable DNA nanosphere for specific sensing of cancer biomarker FEN1 and modulating drug release, showing good stability, sensitivity, and specificity, providing a reliable method for FEN1 imaging and suggesting a powerful strategy for precision medicine.
ANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Wenqian Yu, Junlin Sun, Xiuyuan Wang, Shuyi Yu, Mingzhu Yan, Fuan Wang, Xiaoqing Liu
Summary: This study reports a convenient tumor-specific A2AR inhibition strategy to improve antitumor immune responses using a photo-modulated nanoreactor for spatiotemporally controlled oxygen supply. This nanoreactor not only relieves A2AR-mediated immunosuppression, but also enhances antitumor immunity through photothermal ablation of the tumor and immunogenic cell deaths.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Huimin Wang, Yuqiu He, Jie Wei, Hong Wang, Kang Ma, Yangjie Zhou, Xiaoqing Liu, Xiang Zhou, Fuan Wang
Summary: This study developed a versatile autocatalytic DNA circuit for high-performance in vivo bioanalysis. The circuit showed sensitive and selective detection of analytes, and enabled robust miRNA imaging in living cells and mice. These findings expand the toolbox for accurate diagnosis and programmable therapeutics.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2022)
Article
Biophysics
Yunzhe Cao, Fengye Mo, Yahua Liu, Yu Liu, Gaiping Li, Wenqian Yu, Xiaoqing Liu
Summary: We constructed a portable and sensitive platform that can detect non-glucose target by combining enzyme-encapsulated zeolitic imidazole framework-90 (ZIF-90) with personal glucose meter. This method determined ATP with a remarkably sensitivity of 233 nM and effective recovery in real serum samples.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Materials Science, Multidisciplinary
Jie Feng, Wen-Xiu Ren, Fei Kong, Ce Zhang, Yu-Bin Dong
Summary: The development of photothermal strategies with excellent therapeutic efficiencies under low-temperature conditions is crucial for tumor treatments. By using a multimodal therapeutic agent GA@PCOF@PDA, which combines photodynamic therapy, heat-shock protein down-regulation, and chemotherapy, this study illustrates an efficient approach to design high-performance nanoagents for improved cancer theranostics at low temperatures.
SCIENCE CHINA-MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Jie Wei, Jinhua Shang, Shizhen He, Yu Ouyang, Itamar Willner, Fuan Wang
Summary: In this study, a simple yet versatile enthalpy-driven autocatalytic hybridization chain reaction (AHCR) machinery was constructed for accurate intracellular microRNA imaging in live cells. By introducing two differently designed HCR modules, autonomous cross-invasion and assembly of hyperbranched dsDNA nanostructures were achieved, enabling precise signal localization. The AHCR machinery can be extended for analyzing diverse biomarkers, providing a powerful tool for clinical diagnosis and therapeutic assessment.
Review
Biochemistry & Molecular Biology
Jie Feng, Qing-Yun Huang, Ce Zhang, Seeram Ramakrishna, Yu-Bin Dong
Summary: This article introduces the method of enzyme immobilization using covalent organic frameworks (COFs) and discusses its potential and advantages in improving enzyme stability, recyclability, reducing enzyme contamination, and expanding enzyme applications in the biomedical field. The article summarizes the preparation methods, performances, and latest research applications of various COF-enzyme composites, and also explores the future opportunities and challenges of COF enzyme immobilization technology.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Wen-Xiu Ren, Fei Kong, Yu-Qing Shao, Qing-Yun Huang, Long-Fei Sun, Jie Feng, Yu-Bin Dong
Summary: External light-independent antitumor photodynamic therapy has been successfully achieved using a covalent organic framework (COF)-based host-guest nanosystem. Its highly effective antitumor behavior is fully demonstrated in both H2O2-overexpressed 4T1 and H2O2-less expressed HCT116 and MCF-7 xenograft models.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Yingying Chen, Xue Gong, Yuhui Gao, Yu Shang, Jinhua Shang, Shanshan Yu, Ruomeng Li, Shizhen He, Xiaoqing Liu, Fuan Wang
Summary: Introducing a novel endogenous DNA repairing enzyme-powered pre-selection strategy, a cancer cell-selective catalytic DNA circuit for imaging microRNA with high anti-interference capacity was developed. This circuit offers a reliable amplification strategy for intracellular biomarker assays in living systems.
Article
Chemistry, Multidisciplinary
Chen Hong, Qing Wang, Yingying Chen, Yuhui Gao, Jinhua Shang, Xiaocheng Weng, Xiaoqing Liu, Fuan Wang
Summary: The article introduces a novel method for accurate intracellular imaging of metal ions by utilizing an epigenetic demethylation-regulating DNAzyme system, which repairs and activates DNAzyme to achieve accurate imaging of metal ions.
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
