Associations of plasma trimethylamine N-oxide, choline, carnitine, and betaine with inflammatory and cardiometabolic risk biomarkers and the fecal microbiome in the Multiethnic Cohort Adiposity Phenotype Study

Fecal Microbial Diversity and Structure Are Associated with Diet Quality in the Multiethnic Cohort Adiposity Phenotype Study

(2019) Gertraud Maskarinec et al.   JOURNAL OF NUTRITION

Temporal variability and stability of the fecal microbiome: the Multiethnic Cohort Study

(2018) Benjamin C Fu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Divergent Associations of Plasma Choline and Betaine with Components of Metabolic Syndrome in Middle Age and Elderly Men and Women

(2018) Svetlana V. Konstantinova et al.   JOURNAL OF NUTRITION

Gut Colonization with Methanogenic Archaea Lowers Plasma Trimethylamine N-oxide Concentrations in Apolipoprotein e−/− Mice

(2018) Ali Ramezani et al.   Scientific Reports

Propensity for Intra-abdominal and Hepatic Adiposity Varies Among Ethnic Groups

(2018) Unhee Lim et al.   GASTROENTEROLOGY

Genomics and metagenomics of trimethylamine-utilizing Archaea in the human gut microbiome

(2017) Guillaume Borrel et al.   ISME Journal

Gut Microbiota Metabolites and Risk of Major Adverse Cardiovascular Disease Events and Death: A Systematic Review and Meta‐Analysis of Prospective Studies

(2017) Yoriko Heianza et al.   Journal of the American Heart Association

Uncovering the trimethylamine-producing bacteria of the human gut microbiota

(2017) Silke Rath et al.   Microbiome

Characterization of the gut microbiome in epidemiologic studies: the multiethnic cohort experience

(2016) Benjamin C. Fu et al.   ANNALS OF EPIDEMIOLOGY

Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels

(2016) M. Dambrova et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Trimethylamine-N-oxide (TMAO) response to animal source foods varies among healthy young men and is influenced by their gut microbiota composition: A randomized controlled trial

(2016) Clara E. Cho et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resveratrol Attenuates Trimethylamine- N -Oxide (TMAO)-Induced Atherosclerosis by Regulating TMAO Synthesis and Bile Acid Metabolism via Remodeling of the Gut Microbiota

(2016) Ming-liang Chen et al.   mBio

Microbiota‐Dependent Metabolite Trimethylamine N‐Oxide and Coronary Artery Calcium in the Coronary Artery Risk Development in Young Adults Study (CARDIA)

(2016) Katie A. Meyer et al.   Journal of the American Heart Association

Trimethylamine N‐Oxide Promotes Vascular Inflammation Through Signaling of Mitogen‐Activated Protein Kinase and Nuclear Factor‐κB

(2016) Marcus M. Seldin et al.   Journal of the American Heart Association

Serum Trimethylamine-N-Oxide Is Strongly Related to Renal Function and Predicts Outcome in Chronic Kidney Disease

(2016) Catharina Missailidis et al.   PLoS One

Dietary Phosphatidylcholine Intake and Type 2 Diabetes in Men and Women: Figure 1

(2015) Yanping Li et al.   DIABETES CARE

Serum Trimethylamine-N-Oxide is Elevated in CKD and Correlates with Coronary Atherosclerosis Burden

(2015) J. R. Stubbs et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

(2015) Kymberleigh A. Romano et al.   mBio

Flavin-containing monooxygenase 3 as a potential player in diabetes-associated atherosclerosis

(2015) Ji Miao et al.   Nature Communications

Regression Models for Count Data inR

(2015) Achim Zeileis et al.   Journal of Statistical Software

Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry

(2014) Zeneng Wang et al.   ANALYTICAL BIOCHEMISTRY

Plasma Choline Metabolites and Colorectal Cancer Risk in the Women's Health Initiative Observational Study

(2014) S. Bae et al.   CANCER RESEARCH

Insights Into the Role of the Microbiome in Obesity and Type 2 Diabetes

(2014) Annick V. Hartstra et al.   DIABETES CARE

Dietary trimethylamine N-oxide exacerbates impaired glucose tolerance in mice fed a high fat diet

(2014) Xiang Gao et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

The contributory role of gut microbiota in cardiovascular disease

(2014) W.H. Wilson Tang et al.   JOURNAL OF CLINICAL INVESTIGATION

Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study

(2014) Michael Lever et al.   PLoS One

Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota

(2014) Y. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dietary Choline and Betaine Intakes Vary in an Adult Multiethnic Population

(2013) Kim M. Yonemori et al.   JOURNAL OF NUTRITION

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

(2013) W.H. Wilson Tang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Measurement of marine osmolytes in mammalian serum by liquid chromatography–tandem mass spectrometry

(2011) Crystal C. Lenky et al.   ANALYTICAL BIOCHEMISTRY

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Plasma Lipids and Betaine Are Related in an Acute Coronary Syndrome Cohort

(2011) Michael Lever et al.   PLoS One

Effect of homeostasis model assessment computational method on the definition and associations of insulin resistance

(2010) Olusegun A. Mojiminiyi et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Choline: an essential nutrient for public health

(2009) Steven H Zeisel et al.   NUTRITION REVIEWS