An NIR‐Responsive DNA‐Mediated Nanotetrahedron Enhances the Clearance of Senescent Cells

Granzyme B Functionalized Nanoparticles Targeting Membrane Hsp70‐Positive Tumors for Multimodal Cancer Theranostics

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Quantitative zeptomolar imaging of miRNA cancer markers with nanoparticle assemblies

(2019) Aihua Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A NIR Light Gated DNA Nanodevice for Spatiotemporally Controlled Imaging of MicroRNA in Cells and Animals

(2019) Jian Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The mechanisms of boronate ester formation and fluorescent turn-on in ortho-aminomethylphenylboronic acids

(2019) Xiaolong Sun et al.   Nature Chemistry

Targeting normal and cancer senescent cells as a strategy of senotherapy

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Prediction of Drug-Induced Nephrotoxicity with a Hydroxyl Radical and Caspase Light-Up Dual-Signal Nanoprobe

(2018) Yuling Tong et al.   ANALYTICAL CHEMISTRY

Active Intracellular Delivery of a Cas9/sgRNA Complex Using Ultrasound-Propelled Nanomotors

(2018) Malthe Hansen-Bruhn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

Building superlattices from individual nanoparticles via template-confined DNA-mediated assembly

(2018) Qing-Yuan Lin et al.   SCIENCE

Lysosome activation clears aggregates and enhances quiescent neural stem cell activation during aging

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Near-infrared deep brain stimulation via upconversion nanoparticle–mediated optogenetics

(2018) Shuo Chen et al.   SCIENCE

Self-Assembled Aptamer-Grafted Hyperbranched Polymer Nanocarrier for Targeted and Photoresponsive Drug Delivery

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Direct observation of selective autophagy induction in cells and tissues by self-assembled chiral nanodevice

(2018) Maozhong Sun et al.   Nature Communications

Targeting cellular senescence prevents age-related bone loss in mice

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Cell-targetable DNA nanocapsules for spatiotemporal release of caged bioactive small molecules

(2017) Aneesh T. Veetil et al.   Nature Nanotechnology

Senescent cells: an emerging target for diseases of ageing

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Host response: Granzyme B's roundhouse kick against bacteria

(2017) Ursula Hofer   NATURE REVIEWS MICROBIOLOGY

DNA nanotechnology

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Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice

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Autophagy maintains stemness by preventing senescence

(2016) Laura García-Prat et al.   NATURE

Lattice engineering through nanoparticle–DNA frameworks

(2016) Ye Tian et al.   NATURE MATERIALS

Quantum dot-loaded monofunctionalized DNA icosahedra for single-particle tracking of endocytic pathways

(2016) Dhiraj Bhatia et al.   Nature Nanotechnology

A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood

(2016) Justin Rebo et al.   Nature Communications

Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL

(2016) Reut Yosef et al.   Nature Communications

Bioresponsive materials

(2016) Yue Lu et al.   Nature Reviews Materials

Carbon Nanomaterials for Biological Imaging and Nanomedicinal Therapy

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Dual-Mode Ultrasensitive Quantification of MicroRNA in Living Cells by Chiroplasmonic Nanopyramids Self-Assembled from Gold and Upconversion Nanoparticles

(2015) Si Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Long-term wheel running changes on sensorimotor activity and skeletal muscle in male and female mice of accelerated senescence

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DNA assembly of nanoparticle superstructures for controlled biological delivery and elimination

(2014) Leo Y. T. Chou et al.   Nature Nanotechnology

Characterization of novel markers of senescence and their prognostic potential in cancer

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Stimuli-responsive nanocarriers for drug delivery

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pH- and Photo-Switched Release of Guest Molecules from Mesoporous Silica Supports

(2009) Elena Aznar et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY