Engineered Nanoplatelets for Targeted Delivery of Plasminogen Activators to Reverse Thrombus in Multiple Mouse Thrombosis Models

Platelet decoys inhibit thrombosis and prevent metastatic tumor formation in preclinical models

(2019) Anne-Laure Papa et al.   Science Translational Medicine

Biomimetic Metal-Organic Framework Nanoparticles for Cooperatively Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy

(2019) Huan Min et al.   ADVANCED MATERIALS

Engineering Biomimetic Platesomes for pH‐Responsive Drug Delivery and Enhanced Antitumor Activity

(2019) Guangna Liu et al.   ADVANCED MATERIALS

Erythrocyte Membrane Modified Janus Polymeric Motors for Thrombus Therapy

(2018) Jingxin Shao et al.   ACS Nano

Targeted Treatment of Ischemic and Fibrotic Complications of Myocardial Infarction Using a Dual-Delivery Microgel Therapeutic

(2018) Emily Mihalko et al.   ACS Nano

Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production

(2018) Yukitaka Ito et al.   CELL

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo

(2018) Suping Li et al.   NATURE BIOTECHNOLOGY

2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

(2018) William J. Powers et al.   STROKE

Targeted repair of heart injury by stem cells fused with platelet nanovesicles

(2018) Junnan Tang et al.   Nature Biomedical Engineering

Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis

(2018) Qiangzhe Zhang et al.   Nature Nanotechnology

Platelet bio-nanobubbles as microvascular recanalization nanoformulation for acute ischemic stroke lesion theranostics

(2018) Mingxi Li et al.   Theranostics

Erythrocyte-Inspired Discoidal Polymeric Nanoconstructs Carrying Tissue Plasminogen Activator for the Enhanced Lysis of Blood Clots

(2018) Marianna Colasuonno et al.   ACS Nano

Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy

(2018) Quanyin Hu et al.   Nature Biomedical Engineering

Nanoparticle-mediated local depletion of tumour-associated platelets disrupts vascular barriers and augments drug accumulation in tumours

(2017) Suping Li et al.   Nature Biomedical Engineering

In situ activation of platelets with checkpoint inhibitors for post-surgical cancer immunotherapy

(2017) Chao Wang et al.   Nature Biomedical Engineering

Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus

(2016) Quanyin Hu et al.   ADVANCED MATERIALS

Alternatives to allogeneic platelet transfusion

(2016) Michael J. R. Desborough et al.   BRITISH JOURNAL OF HAEMATOLOGY

Antithrombotic Therapy for VTE Disease

(2016) Clive Kearon et al.   CHEST

Liposomal nanocarriers for plasminogen activators

(2016) Stepan Koudelka et al.   JOURNAL OF CONTROLLED RELEASE

Multifunctional Thrombin-Activatable Polymer Capsules for Specific Targeting to Activated Platelets

(2015) Sylvia T. Gunawan et al.   ADVANCED MATERIALS

Smart Albumin-Biomineralized Nanocomposites for Multimodal Imaging and Photothermal Tumor Ablation

(2015) Yong Wang et al.   ADVANCED MATERIALS

Nanoparticle biointerfacing by platelet membrane cloaking

(2015) Che-Ming J. Hu et al.   NATURE

Progress in Intravenous Thrombolytic Therapy for Acute Stroke

(2015) Randolph S. Marshall   JAMA Neurology

Platelet-like Nanoparticles: Mimicking Shape, Flexibility, and Surface Biology of Platelets To Target Vascular Injuries

(2014) Aaron C. Anselmo et al.   ACS Nano

A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling

(2014) Daniel C Leslie et al.   NATURE BIOTECHNOLOGY

The aryl hydrocarbon receptor directs hematopoietic progenitor cell expansion and differentiation

(2013) B. W. Smith et al.   BLOOD

t-PA-specific modulation of a human blood-brain barrier model involves plasmin-mediated activation of the Rho kinase pathway in astrocytes

(2012) B. Niego et al.   BLOOD

Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels

(2012) N. Korin et al.   SCIENCE

Mechanisms underlying FeCl3-induced arterial thrombosis

(2011) A. ECKLY et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Arterial thrombus formation in cardiovascular disease

(2011) Giuseppe Lippi et al.   Nature Reviews Cardiology

Improved Prediction of Poor Outcome After Thrombolysis Using Conservative Definitions of Symptomatic Hemorrhage

(2011) Christoph Gumbinger et al.   STROKE

Cerebrovascular Thromboprophylaxis in Mice by Erythrocyte-Coupled Tissue-Type Plasminogen Activator

(2008) Kristina Danielyan et al.   CIRCULATION

Triggers, targets and treatments for thrombosis

(2008) Nigel Mackman   NATURE

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

(2008) Enming J Su et al.   NATURE MEDICINE

Mechanisms of Thrombus Formation

(2008) Bruce Furie et al.   NEW ENGLAND JOURNAL OF MEDICINE