Poly(cyclodextrin)‐Polydrug Nanocomplexes as Synthetic Oncolytic Virus for Locoregional Melanoma Chemoimmunotherapy

Augmenting the synergies of chemotherapy and immunotherapy through drug delivery

(2019) Jihoon Kim et al.   Acta Biomaterialia

Antitumor effect of oncolytic virus and paclitaxel encapsulated in extracellular vesicles for lung cancer treatment

(2018) M. Garofalo et al.   JOURNAL OF CONTROLLED RELEASE

Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients treated with neoadjuvant therapy

(2018) Carsten Denkert et al.   LANCET ONCOLOGY

Combining Immune Checkpoint Inhibitors With Conventional Cancer Therapy

(2018) Yiyi Yan et al.   Frontiers in Immunology

Stimuli-Responsive Nano-Architecture Drug-Delivery Systems to Solid Tumor Micromilieu: Past, Present, and Future Perspectives

(2018) Hossam S. El-Sawy et al.   ACS Nano

Paclitaxel: What has been done and the challenges remain ahead

(2017) Ezequiel Bernabeu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Combination of nitric oxide and drug delivery systems: tools for overcoming drug resistance in chemotherapy

(2017) Jihoon Kim et al.   JOURNAL OF CONTROLLED RELEASE

pH-Responsive mineralized nanoparticles as stable nanocarriers for intracellular nitric oxide delivery

(2016) Hong Jae Lee et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Flexible Macromolecule versus Rigid Particle Retention in the Injected Skin and Accumulation in Draining Lymph Nodes Are Differentially Influenced by Hydrodynamic Size

(2016) Nathan Andrew Rohner et al.   ACS Biomaterials-Science & Engineering

Flexible Macromolecule versus Rigid Particle Retention in the Injected Skin and Accumulation in Draining Lymph Nodes Are Differentially Influenced by Hydrodynamic Size

(2016) Nathan Andrew Rohner et al.   ACS Biomaterials Science & Engineering

Cancer nanomedicine: is targeting our target?

(2016) Twan Lammers et al.   Nature Reviews Materials

Into the clinic: Talimogene laherparepvec (T-VEC), a first-in-class intratumoral oncolytic viral therapy

(2016) Hasan Rehman et al.   Journal for ImmunoTherapy of Cancer

A pH-Responsive Carrier System that Generates NO Bubbles to Trigger Drug Release and Reverse P-Glycoprotein-Mediated Multidrug Resistance

(2015) Ming-Fan Chung et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Oncolytic viruses: a new class of immunotherapy drugs

(2015) Howard L. Kaufman et al.   NATURE REVIEWS DRUG DISCOVERY

Nitric oxide synthase in innate and adaptive immunity: an update

(2015) Christian Bogdan   TRENDS IN IMMUNOLOGY

Immunogenic cell death inducers as anticancer agents

(2015) Oliver Kepp et al.   Oncotarget

Mechanistic Analysis of Taxol-induced Multidrug Resistance in an Ovarian Cancer Cell Line

(2014) Ning-Ning Wang et al.   Asian Pacific Journal of Cancer Prevention

Nitric Oxide Releasing d-α-Tocopheryl Polyethylene Glycol Succinate for Enhancing Antitumor Activity of Doxorubicin

(2014) Qingle Song et al.   MOLECULAR PHARMACEUTICS

Biopolymer implants enhance the efficacy of adoptive T-cell therapy

(2014) Sirkka B Stephan et al.   NATURE BIOTECHNOLOGY

Injectable, spontaneously assembling, inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy

(2014) Jaeyun Kim et al.   NATURE BIOTECHNOLOGY

Localized Oncolytic Virotherapy Overcomes Systemic Tumor Resistance to Immune Checkpoint Blockade Immunotherapy

(2014) D. Zamarin et al.   Science Translational Medicine

Poly-cyclodextrin and poly-paclitaxel nano-assembly for anticancer therapy

(2014) Ran Namgung et al.   Nature Communications

S-Nitrosoglutathione

(2013) Katarzyna A. Broniowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Endolysosomal environment-responsive photodynamic nanocarrier to enhance cytosolic drug delivery via photosensitizer-mediated membrane disruption

(2013) Chung-Sung Lee et al.   BIOMATERIALS

Targeting the tumor-draining lymph node with adjuvanted nanoparticles reshapes the anti-tumor immune response

(2013) Susan N. Thomas et al.   BIOMATERIALS

Synergy between chemotherapeutic agents and CTLA-4 blockade in preclinical tumor models

(2013) Maria Jure-Kunkel et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Molecular mechanisms of ATP secretion during immunogenic cell death

(2013) I Martins et al.   CELL DEATH AND DIFFERENTIATION

Reciprocal Relationship between Myeloid-Derived Suppressor Cells and T Cells

(2013) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY

A platform for nitric oxide delivery

(2013) Jihoon Kim et al.   Journal of Materials Chemistry B

Modulation of MDR1 and MRP3 Gene Expression in Lung Cancer Cells after Paclitaxel and Carboplatin Exposure

(2012) Consolación Melguizo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Tumor-Expressed Inducible Nitric Oxide Synthase Controls Induction of Functional Myeloid-Derived Suppressor Cells through Modulation of Vascular Endothelial Growth Factor Release

(2012) P. Jayaraman et al.   JOURNAL OF IMMUNOLOGY

Application of paclitaxel in low non-cytotoxic doses supports vaccination with melanoma antigens in normal mice

(2012) Alexandra Sevko et al.   Journal of Immunotoxicology

Nitric Oxide Modulates TGF- -Directive Signals To Suppress Foxp3+ Regulatory T Cell Differentiation and Potentiate Th1 Development

(2011) S.-W. Lee et al.   JOURNAL OF IMMUNOLOGY

Thunder and Lightning: Immunotherapy and Oncolytic Viruses Collide

(2011) Alan Melcher et al.   MOLECULAR THERAPY

CD4+Foxp3+ Regulatory T-cell Impairment by Paclitaxel is Independent of Toll-like Receptor 4

(2011) Y. Zhu et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Differential effects of Paclitaxel on dendritic cell function

(2010) Justin John et al.   BMC IMMUNOLOGY

Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice

(2010) Lukas W. Pfannenstiel et al.   CELLULAR IMMUNOLOGY

Nitric oxide and P-glycoprotein modulate the phagocytosis of colon cancer cells

(2010) Joanna Kopecka et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells

(2010) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY

A Mechanism of Release of Calreticulin from Cells During Apoptosis

(2010) Joanna M. Tarr et al.   JOURNAL OF MOLECULAR BIOLOGY

Paclitaxel acts as an adjuvant to promote both Th1 and Th2 immune responses induced by ovalbumin in mice

(2010) Lin Yuan et al.   VACCINE

Classification of Chemotherapeutic Agents Based on Their Differential In vitro Effects on Dendritic Cells

(2009) H. Tanaka et al.   CANCER RESEARCH

Paclitaxel and immune system

(2009) Aqeel Javeed et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chemotherapeutic Agents in Noncytotoxic Concentrations Increase Antigen Presentation by Dendritic Cells via an IL-12-Dependent Mechanism

(2009) G. V. Shurin et al.   JOURNAL OF IMMUNOLOGY

Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations

(2009) Ramon Kaneno et al.   Journal of Translational Medicine

Ascorbic acid efflux and re-uptake in endothelial cells: maintenance of intracellular ascorbate

(2009) James M. May et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

iNOS activity is necessary for the cytotoxic and immunogenic effects of doxorubicin in human colon cancer cells

(2009) Sara De Boo et al.   Molecular Cancer

Differential impairment of regulatory T cells rather than effector T cells by paclitaxel-based chemotherapy

(2008) Lei Zhang et al.   CLINICAL IMMUNOLOGY

Migration of Dendritic Cell Subsets and their Precursors

(2007) Gwendalyn J. Randolph et al.   Annual Review of Immunology