Plant-Produced Anti-Enterovirus 71 (EV71) Monoclonal Antibody Efficiently Protects Mice Against EV71 Infection

Monoclonal antibody against EV71 3Dpol inhibits the polymerase activity of RdRp and virus replication

(2019) Yaoming Li et al.   BMC IMMUNOLOGY

Identification and production of mouse scFv to specific epitope of enterovirus-71 virion protein-2 (VP2)

(2018) Jeeraphong Thanongsaksrikul et al.   ARCHIVES OF VIROLOGY

The Effect of School Closure on Hand, Foot, and Mouth Disease Transmission in Singapore: A Modeling Approach

(2018) Yirong Chen et al.   AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Clinical and aetiological study of hand, foot and mouth disease in southern Vietnam, 2013–2015: Inpatients and outpatients

(2018) Minh Tu Van Hoang et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Effective in vivo therapeutic IgG antibody against VP3 of enterovirus 71 with receptor-competing activity

(2017) Qiang Jia et al.   Scientific Reports

EV71 vaccine, a new tool to control outbreaks of hand, foot and mouth disease (HFMD)

(2016) Qun-ying Mao et al.   Expert Review of Vaccines

Techno-economic analysis of a transient plant-based platform for monoclonal antibody production

(2016) Somen Nandi et al.   mAbs

Structural Basis for Recognition of Human Enterovirus 71 by a Bivalent Broadly Neutralizing Monoclonal Antibody

(2016) Xiaohua Ye et al.   PLoS Pathogens

A synthetic biology standard for Chinese Hamster Ovary cell genome monitoring and contaminant detection by polymerase chain reaction

(2016) Alexander Templar et al.   SpringerPlus

Generation and characterization of a protective mouse monoclonal antibody against human enterovirus 71

(2015) Yong-Qiang Deng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Plant-made vaccines against West Nile virus are potent, safe, and economically feasible

(2015) Qiang Chen   Biotechnology Journal

Single Neutralizing Monoclonal Antibodies Targeting the VP1 GH Loop of Enterovirus 71 Inhibit both Virus Attachment and Internalization during Viral Entry

(2015) Zhiqiang Ku et al.   JOURNAL OF VIROLOGY

Regulatory approval and a first-in-human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants

(2015) Julian K-C. Ma et al.   PLANT BIOTECHNOLOGY JOURNAL

A bivalent virus-like particle based vaccine induces a balanced antibody response against both enterovirus 71 and norovirus in mice

(2015) Xiaoli Wang et al.   VACCINE

High-yield production of recombinant virus-like particles of enterovirus 71 in Pichia pastoris and their protective efficacy against oral viral challenge in mice

(2015) Chao Zhang et al.   VACCINE

Clinical Safety and Immunogenicity of Tumor-Targeted, Plant-Made Id-KLH Conjugate Vaccines for Follicular Lymphoma

(2015) Daniel Tusé et al.   Biomed Research International

Plant-made vaccines against West Nile virus are potent, safe, and economically feasible

(2015) Qiang Chen   Biotechnology Journal

Monoclonal neutralizing antibodies against EV71 screened from mice immunized with yeast-produced virus-like particles

(2015) Tao Lin et al.   VIROLOGICA SINICA

A combination vaccine comprising of inactivated enterovirus 71 and coxsackievirus A16 elicits balanced protective immunity against both viruses

(2014) Yicun Cai et al.   VACCINE

A Novel Universal Neutralizing Monoclonal Antibody against Enterovirus 71 That Targets the Highly Conserved “Knob” Region of VP3 Protein

(2014) Tanja K. Kiener et al.   PLoS Neglected Tropical Diseases

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans

(2013) Leonard Both et al.   FASEB JOURNAL

Neutralizing Antibodies Induced by Recombinant Virus-Like Particles of Enterovirus 71 Genotype C4 Inhibit Infection at Pre- and Post-attachment Steps

(2013) Zhiqiang Ku et al.   PLoS One

Study of the Integrated Immune Response Induced by an Inactivated EV71 Vaccine

(2013) Longding Liu et al.   PLoS One

Development of murine monoclonal antibodies with potent neutralization effects on enterovirus 71

(2012) Zhiqiang Ku et al.   JOURNAL OF VIROLOGICAL METHODS

Characterization of an Isotype-Dependent Monoclonal Antibody against Linear Neutralizing Epitope Effective for Prophylaxis of Enterovirus 71 Infection

(2012) Xiao Fang Lim et al.   PLoS One

Optimized development of a candidate strain of inactivated EV71 vaccine and analysis of its immunogenicity in rhesus monkeys

(2011) Chenghong Dong et al.   Human vaccines & immunotherapeutics

Formalin-inactivated vaccine provokes cross-protective immunity in a mouse model of human enterovirus 71 infection

(2011) Emily Jane Bek et al.   VACCINE

Identification and characterization of a cross-neutralization epitope of Enterovirus 71

(2011) Chia-Chyi Liu et al.   VACCINE

Immunoprotection elicited by an enterovirus type 71 experimental inactivated vaccine in mice and rhesus monkeys

(2011) Chenghong Dong et al.   VACCINE

High-level rapid production of full-size monoclonal antibodies in plants by a single-vector DNA replicon system

(2010) Zhong Huang et al.   BIOTECHNOLOGY AND BIOENGINEERING

Clinical features, diagnosis, and management of enterovirus 71

(2010) Mong How Ooi et al.   LANCET NEUROLOGY

Monoclonal antibody produced in plants efficiently treats West Nile virus infection in mice

(2010) H. Lai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined peptides of human enterovirus 71 protect against virus infection in mice

(2010) Jiang Ning Liu et al.   VACCINE

Enterovirus 71 virus-like particle vaccine: Improved production conditions for enhanced yield

(2010) Cheng-Yu Chung et al.   VACCINE

Monoclonal antibody induced with inactived EV71-Hn2 virus protects mice against lethal EV71-Hn2 virus infection

(2010) Guo-hui Chang et al.   Virology Journal

Immunization with virus-like particles of enterovirus 71 elicits potent immune responses and protects mice against lethal challenge

(2008) Yao-Chi Chung et al.   VACCINE