Myelin Pathology: Involvement of Molecular Chaperones and the Promise of Chaperonotherapy

Heat Shock Proteins in Alzheimer’s Disease: Role and Targeting

(2018) Claudia Campanella et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

T-complex protein 1-ring complex enhances retrograde axonal transport by modulating tau phosphorylation

(2018) Xu-Qiao Chen et al.   TRAFFIC

Targeting chaperonin containing TCP1 (CCT) as a molecular therapeutic for small cell lung cancer

(2017) Ana C. Carr et al.   Oncotarget

Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy

(2017) Jose H. Pereira et al.   Scientific Reports

Hypomyelinating Leukodystrophy due to HSPD1 Mutations: A New Patient

(2016) Maria Kusk et al.   NEUROPEDIATRICS

Hypomyelinating leukodystrophy-associated missense mutation in HSPD1 blunts mitochondrial dynamics

(2015) Yuki Miyamoto et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A Human Interactome in Three Quantitative Dimensions Organized by Stoichiometries and Abundances

(2015) Marco Y. Hein et al.   CELL

Leukoencephalopathy and early death associated with an Ashkenazi-Jewish founder mutation in the Hikeshi gene

(2015) Simon Edvardson et al.   JOURNAL OF MEDICAL GENETICS

Biochemical Characterization of Mutants in Chaperonin Proteins CCT4 and CCT5 Associated with Hereditary Sensory Neuropathy

(2014) Oksana A. Sergeeva et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A human CCT5 gene mutation causing distal neuropathy impairs hexadecamer assembly in an archaeal model

(2014) Wonki Min et al.   Scientific Reports

Molecular Chaperone Dysfunction in Neurodegenerative Diseases and Effects of Curcumin

(2014) Panchanan Maiti et al.   Biomed Research International

Molecular Chaperone Disorders: Defective Hsp60 in Neurodegeneration

(2013) Peter Bross et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

The Chaperonopathies - Diseases with Defective Molecular Chaperones

(2013) Giovanni Li Volti   EUROPEAN JOURNAL OF HISTOCHEMISTRY

Systematic approaches to central nervous system myelin

(2012) Patricia de Monasterio-Schrader et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pharmacological chaperones for human  -N-acetylgalactosaminidase

(2012) N. E. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A method and server for predicting damaging missense mutations

(2010) Ivan A Adzhubei et al.   NATURE METHODS

Molecular architecture of myelinated peripheral nerves is supported by calorie restriction with aging

(2009) Sunitha Rangaraju et al.   AGING CELL

Mitochondrial Hsp60 Chaperonopathy Causes an Autosomal-Recessive Neurodegenerative Disorder Linked to Brain Hypomyelination and Leukodystrophy

(2008) Daniella Magen et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Hsp60-(p.V98I) Mutation Associated with Hereditary Spastic Paraplegia SPG13 Compromises Chaperonin Function Bothin Vitroandin Vivo

(2008) Peter Bross et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structure of CCT–Hsc70NBD suggests a mechanism for Hsp70 delivery of substrates to the chaperonin

(2008) Jorge Cuéllar et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pharmacological induction of the heat shock response improves myelination in a neuropathic model

(2008) Sunitha Rangaraju et al.   NEUROBIOLOGY OF DISEASE