Pros and Cons of Use of Mitochondria-Targeted Antioxidants

Physiologic Implications of Reactive Oxygen Species Production by Mitochondrial Complex I Reverse Electron Transport

(2019) John O. Onukwufor et al.   Antioxidants

Mitochondria-targeted antioxidant therapy with MitoQ ameliorates aortic stiffening in old mice

(2018) Rachel A. Gioscia-Ryan et al.   JOURNAL OF APPLIED PHYSIOLOGY

Oxygen-dependence of mitochondrial ROS production as detected by Amplex Red assay

(2018) Vera G. Grivennikova et al.   Redox Biology

Neuroprotective Effects of Mitochondria-Targeted Plastoquinone in a Rat Model of Neonatal Hypoxic–Ischemic Brain Injury

(2018) Denis Silachev et al.   MOLECULES

Mitochondrial superoxide generation induces a parkinsonian phenotype in zebrafish and huntingtin aggregation in human cells

(2018) Brígida R. Pinho et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondria-Targeted Drugs

(2018) Roman A. Zinovkin et al.   Current Molecular Pharmacology

ROS homeostasis and metabolism: a dangerous liason in cancer cells

(2016) E Panieri et al.   Cell Death & Disease

The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients

(2016) Irene Escribano-Lopez et al.   Redox Biology

Cardiomyocyte mitochondrial oxidative stress and cytoskeletal breakdown in the heart with a primary volume overload

(2015) Danielle M. Yancey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The mitochondria-targeted anti-oxidant MitoQ decreases ischemia-reperfusion injury in a murine syngeneic heart transplant model

(2015) Anna J. Dare et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

The Mitochondrion as a Key Regulator of Ischaemic Tolerance and Injury

(2014) Denis N. Silachev et al.   Heart Lung and Circulation

Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release

(2014) Dmitry B. Zorov et al.   PHYSIOLOGICAL REVIEWS

Role of oxidative stress and mitochondria in onset of urinary bladder dysfunction under acute urine retention

(2013) V. I. Kirpatovsky et al.   BIOCHEMISTRY-MOSCOW

Protective effect of mitochondria-targeted antioxidants in an acute bacterial infection

(2013) E. Y. Plotnikov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria-targeted antioxidant SkQR1 ameliorates gentamycin-induced renal failure and hearing loss

(2012) S. S. Jankauskas et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone antioxidant SkQR1 decreases trauma-induced neurological deficit in rat

(2012) N. K. Isaev et al.   BIOCHEMISTRY-MOSCOW

Mild uncoupling of respiration and phosphorylation as a mechanism providing nephro- and neuroprotective effects of penetrating cations of the SkQ family

(2012) E. Y. Plotnikov et al.   BIOCHEMISTRY-MOSCOW

Mitochondrial-Targeted Plastoquinone Derivatives. Effect on Senescence and Acute Age-Related Pathologies

(2011) M. V. Skulachev et al.   CURRENT DRUG TARGETS

New-generation Skulachev ions exhibiting nephroprotective and neuroprotective properties

(2010) E. Y. Plotnikov et al.   BIOCHEMISTRY-MOSCOW

Mechanisms and Function of DUOX in Epithelia of the Lung

(2009) Horst Fischer   ANTIOXIDANTS & REDOX SIGNALING

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and Age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke)

(2009) L. E. Bakeeva et al.   BIOCHEMISTRY-MOSCOW