Immunogenicity and Protection from Receptor-Binding Domains of Toxins as Potential Vaccine Candidates for Clostridium difficile

Clostridium difficile Toxoid Vaccine Candidate Confers Broad Protection against a Range of Prevalent Circulating Strains in a Nonclinical Setting

(2018) Laurence Quemeneur et al.   INFECTION AND IMMUNITY

Protection Against Helicobacter pylori Infection in BALB/c Mouse Model by Oral Administration of Multivalent Epitope-Based Vaccine of Cholera Toxin B Subunit-HUUC

(2018) Xing Pan et al.   Frontiers in Immunology

Optimization of the Production Process and Characterization of the Yeast-Expressed SARS-CoV Recombinant Receptor-Binding Domain (RBD219-N1), a SARS Vaccine Candidate

(2017) Wen-Hsiang Chen et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Clostridium difficile chimeric toxin receptor binding domain vaccine induced protection against different strains in active and passive challenge models

(2017) Jing-Hui Tian et al.   VACCINE

Safety and immunogenicity of Clostridium difficile toxoid vaccine in Japanese adults

(2017) Osamu Matsuoka et al.   Human Vaccines & Immunotherapeutics

Frizzled proteins are colonic epithelial receptors for C. difficile toxin B

(2016) Liang Tao et al.   NATURE

A Combination of Three Fully Human Toxin A- and Toxin B-Specific Monoclonal Antibodies Protects against Challenge with Highly Virulent Epidemic Strains of Clostridium difficile in the Hamster Model

(2015) Natalie G. Anosova et al.   Clinical and Vaccine Immunology

Burden of Clostridium difficile Infection in the United States

(2015) Fernanda C. Lessa et al.   NEW ENGLAND JOURNAL OF MEDICINE

Identification of an epithelial cell receptor responsible forClostridium difficileTcdB-induced cytotoxicity

(2015) Michelle E. LaFrance et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression, purification and characterization of the receptor-binding domain of botulinum neurotoxin serotype B as a vaccine candidate

(2015) Alon Ben David et al.   PROTEIN EXPRESSION AND PURIFICATION

Passive and active immunization strategies against Clostridium difficile infections: State of the art

(2014) Assaf Mizrahi et al.   ANAEROBE

Chondroitin sulfate proteoglycan 4 functions as the cellular receptor for Clostridium difficile toxin B

(2014) Pengfei Yuan et al.   CELL RESEARCH

Clostridium difficileinfection: molecular pathogenesis and novel therapeutics

(2014) Ardeshir Rineh et al.   Expert Review of Anti-Infective Therapy

Clostridium difficileInfection: A Worldwide Disease

(2014) Kristin E. Burke et al.   Gut and Liver

An Optimized, Synthetic DNA Vaccine Encoding the Toxin A and Toxin B Receptor Binding Domains of Clostridium difficile Induces Protective Antibody ResponsesIn Vivo

(2014) Scott M. Baliban et al.   INFECTION AND IMMUNITY

Cholera toxin B subunit acts as a potent systemic adjuvant for HIV-1 DNA vaccination intramuscularly in mice

(2014) Jue Hou et al.   Human Vaccines & Immunotherapeutics

Protective Efficacy Induced by Recombinant Clostridium difficile Toxin Fragments

(2013) Rosanna Leuzzi et al.   INFECTION AND IMMUNITY

Systemic antibody responses induced by a two-component Clostridium difficile toxoid vaccine protect against C. difficile-associated disease in hamsters

(2013) N. G. Anosova et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Duodenal Infusion of Donor Feces for Recurrent Clostridium difficile

(2013) Els van Nood et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Chimeric Toxin Vaccine Protects against Primary and Recurrent Clostridium difficile Infection

(2012) Haiying Wang et al.   INFECTION AND IMMUNITY

Clostridium difficile: Development of a novel candidate vaccine

(2012) Ginamarie Foglia et al.   VACCINE

Advances in pathogenesis, diagnosis and management of CDI

(2011) Dale N. Gerding et al.   Nature Reviews Gastroenterology & Hepatology

Adenovirus-based vaccination against Clostridium difficile toxin A allows for rapid humoral immunity and complete protection from toxin A lethal challenge in mice

(2011) Sergey S. Seregin et al.   VACCINE

Structural organization of the functional domains of Clostridium difficile toxins A and B

(2010) R. N. Pruitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium

(2009) Richard A Stabler et al.   GENOME BIOLOGY

Functional properties of the carboxy-terminal host cell-binding domains of the two toxins, TcdA and TcdB, expressed by Clostridium difficile

(2008) T. Dingle et al.   GLYCOBIOLOGY