Genomic prediction of depression risk and resilience under stress

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

(2019) David M. Howard et al.   NATURE NEUROSCIENCE

Prospective study of polygenic risk, protective factors, and incident depression following combat deployment in US Army soldiers

(2019) Karmel W. Choi et al.   PSYCHOLOGICAL MEDICINE

Accuracy of Patient Health Questionnaire-9 (PHQ-9) for screening to detect major depression: individual participant data meta-analysis

(2019) Brooke Levis et al.   BMJ-British Medical Journal

County-Level Trends in Suicide Rates in the U.S., 2005–2015

(2018) Lauren M. Rossen et al.   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Personalized medicine: Prediction of disease vulnerability in mood disorders

(2018) Stefania Prendes-Alvarez et al.   NEUROSCIENCE LETTERS

The value of polygenic analyses in psychiatry

(2018) Christel M. Middeldorp et al.   World Psychiatry

Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways

(2018) David M. Howard et al.   Nature Communications

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Genetic risk of major depressive disorder: the moderating and mediating effects of neuroticism and psychological resilience on clinical and self-reported depression

(2017) L. B. Navrady et al.   PSYCHOLOGICAL MEDICINE

Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

(2016) Aysu Okbay et al.   NATURE GENETICS

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

(2016) Craig L Hyde et al.   NATURE GENETICS

Developing and evaluating polygenic risk prediction models for stratified disease prevention

(2016) Nilanjan Chatterjee et al.   NATURE REVIEWS GENETICS

Prevalence of Depression and Depressive Symptoms Among Resident Physicians

(2015) Douglas A. Mata et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Sparse whole-genome sequencing identifies two loci for major depressive disorder

(2015) Na Cai et al.   NATURE

Protective alleles and modifier variants in human health and disease

(2015) Andrew R. Harper et al.   NATURE REVIEWS GENETICS

Web-Based Cognitive Behavioral Therapy Intervention for the Prevention of Suicidal Ideation in Medical Interns

(2015) Constance Guille et al.   JAMA Psychiatry

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

mediation:RPackage for Causal Mediation Analysis

(2015) Dustin Tingley et al.   Journal of Statistical Software

PRSice: Polygenic Risk Score software

(2014) Jack Euesden et al.   BIOINFORMATICS

Effect of polygenic risk scores on depression in childhood trauma

(2014) Wouter J. Peyrot et al.   BRITISH JOURNAL OF PSYCHIATRY

Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis

(2014) K. L. Musliner et al.   PSYCHOLOGICAL MEDICINE

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

The Science of Resilience: Implications for the Prevention and Treatment of Depression

(2012) S. M. Southwick et al.   SCIENCE

A Prospective Cohort Study Investigating Factors Associated With Depression During Medical Internship

(2010) Srijan Sen et al.   ARCHIVES OF GENERAL PSYCHIATRY