Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration

Distribution of insulin in trigeminal nerve and brain after intranasal administration

(2019) Jeffrey J. Lochhead et al.   Scientific Reports

Glymphatic System Function in Relation to Anesthesia and Sleep States

(2019) Helene Benveniste et al.   ANESTHESIA AND ANALGESIA

Anatomical basis and physiological role of cerebrospinal fluid transport through the murine cribriform plate

(2019) Jordan N Norwood et al.   eLife

Lymphatic clearance is the main drainage route of lamotrigine‐loaded micelles following delivery to the brain

(2019) Jiaqi Yan et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Meningeal lymphatic vessels at the skull base drain cerebrospinal fluid

(2019) Ji Hoon Ahn et al.   NATURE

Convective influx/glymphatic system: tracers injected into the CSF enter and leave the brain along separate periarterial basement membrane pathways

(2018) Nazira J. Albargothy et al.   ACTA NEUROPATHOLOGICA

The role of brain barriers in fluid movement in the CNS: is there a ‘glymphatic’ system?

(2018) N. Joan Abbott et al.   ACTA NEUROPATHOLOGICA

The Route by Which Intranasally Delivered Stem Cells Enter the Central Nervous System

(2018) Carlos Galeano et al.   CELL TRANSPLANTATION

Delivery of immunoglobulin G antibodies to the rat nervous system following intranasal administration: Distribution, dose-response, and mechanisms of delivery

(2018) Niyanta N. Kumar et al.   JOURNAL OF CONTROLLED RELEASE

Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain

(2018) Qiaoli Ma et al.   ACTA NEUROPATHOLOGICA

Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

(2018) Humberto Mestre et al.   Nature Communications

Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery

(2017) Michelle E. Pizzo et al.   JOURNAL OF PHYSIOLOGY-LONDON

Lymphatic Clearance of the Brain: Perivascular, Paravascular and Significance for Neurodegenerative Diseases

(2016) Erik N. T. P. Bakker et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Specificity, Size, and Frequency of Spaces That Characterize the Mechanism of Bulk Transepithelial Transport of Prions in the Nasal Cavities of Hamsters and Mice

(2016) A. E. Kincaid et al.   JOURNAL OF VIROLOGY

Drug Transporters in the Central Nervous System

(2015) Bruno Stieger et al.   CLINICAL PHARMACOKINETICS

Rapid Transport within Cerebral Perivascular Spaces Underlies Widespread Tracer Distribution in the Brain after Intranasal Administration

(2015) Jeffrey J Lochhead et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

(2015) Aleksanteri Aspelund et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural and functional features of central nervous system lymphatic vessels

(2015) Antoine Louveau et al.   NATURE

Pathogens Penetrating the Central Nervous System: Infection Pathways and the Cellular and Molecular Mechanisms of Invasion

(2014) Samantha J. Dando et al.   CLINICAL MICROBIOLOGY REVIEWS

Cerebral Arterial Pulsation Drives Paravascular CSF-Interstitial Fluid Exchange in the Murine Brain

(2013) J. J. Iliff et al.   JOURNAL OF NEUROSCIENCE

Migration of monocytes after intracerebral injection at entorhinal cortex lesion site

(2012) Miriam Kaminski et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Intranasal delivery of insulin via the olfactory nerve pathway

(2012) Dan B. Renner et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid  

(2012) J. J. Iliff et al.   Science Translational Medicine

Effects of Localized Hydrophilic Mannitol and Hydrophobic Nelfinavir Administration Targeted to Olfactory Epithelium on Brain Distribution

(2011) John Douglas Hoekman et al.   AAPS PHARMSCITECH

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

Enhanced Analgesic Responses After Preferential Delivery of Morphine and Fentanyl to the Olfactory Epithelium in Rats

(2011) John D. Hoekman et al.   ANESTHESIA AND ANALGESIA

Microbes' roadmap to neurons

(2011) Krister Kristensson   NATURE REVIEWS NEUROSCIENCE

Topographic study on nerve-associated lymphatic vessels in the murine craniofacial region by immunohistochemistry and electron microscopy

(2009) Masahide Furukawa et al.   BIOMEDICAL RESEARCH-TOKYO

The olfactory vector hypothesis of neurodegenerative disease: Is it viable?

(2008) Richard L. Doty   ANNALS OF NEUROLOGY

Intranasal delivery of transforming growth factor-beta1 in mice after stroke reduces infarct volume and increases neurogenesis in the subventricular zone

(2008) Minmin Ma et al.   BMC NEUROSCIENCE

Epithelial and endothelial barriers in the olfactory region of the nasal cavity of the rat

(2008) Hartwig Wolburg et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Molecular composition of tight and adherens junctions in the rat olfactory epithelium and fila

(2008) Axel Steinke et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Delivery of interferon-β to the monkey nervous system following intranasal administration

(2008) R.G. Thorne et al.   NEUROSCIENCE

Direct transport of VEGF from the nasal cavity to brain

(2008) Ji-Ping Yang et al.   NEUROSCIENCE LETTERS