FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
FRAX597, a PAK1 inhibitor, synergistically reduces pancreatic cancer growth when combined with gemcitabine
Authors
Keywords
Pancreatic adenocarcinoma, PAK1, Gemcitabine, Proliferation, Orthotopic murine model
Journal
BMC CANCER
Volume 16, Issue 1, Pages -
Publisher
Springer Nature
Online
2016-01-16
DOI
10.1186/s12885-016-2057-z
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Role of p21-Activated Kinases in Pancreatic Cancer
- (2015) Dannel Yeo et al. PANCREAS
- High Expression of HIF1a Is a Predictor of Clinical Outcome in Patients with Pancreatic Ductal Adenocarcinomas and Correlated to PDGFA, VEGF, and bFGF
- (2015) Andreas-Claudius Hoffmann et al. NEOPLASIA
- Reduced expression of p21-activated protein kinase 1 correlates with poor histological differentiation in pancreatic cancer
- (2014) Juan Han et al. BMC CANCER
- Glaucarubinone and gemcitabine synergistically reduce pancreatic cancer growth via down-regulation of P21-activated kinases
- (2014) Dannel Yeo et al. CANCER LETTERS
- Projecting Cancer Incidence and Deaths to 2030: The Unexpected Burden of Thyroid, Liver, and Pancreas Cancers in the United States
- (2014) L. Rahib et al. CANCER RESEARCH
- Gemcitabine: Metabolism and molecular mechanisms of action, sensitivity and chemoresistance in pancreatic cancer
- (2014) Lucas de Sousa Cavalcante et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Transcriptional regulation of fibronectin by p21-activated kinase-1 modulates pancreatic tumorigenesis
- (2014) S Jagadeeshan et al. ONCOGENE
- p21-Activated Kinase 4 (PAK4) as a Predictive Marker of Gemcitabine Sensitivity in Pancreatic Cancer Cell Lines
- (2014) Sung-Ung Moon et al. Cancer Research and Treatment
- P21-activated kinase 1 promotes colorectal cancer survival by up-regulation of hypoxia-inducible factor-1α
- (2013) Kevin H. Liu et al. CANCER LETTERS
- FRAX597, a Small Molecule Inhibitor of the p21-activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-associated Schwannomas
- (2013) Silvia Licciulli et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Comparison of Two Syngeneic Orthotopic Murine Models of Pancreatic Adenocarcinoma
- (2013) Mehrdad Nikfarjam et al. JOURNAL OF INVESTIGATIVE SURGERY
- p21-Activated Kinase 1 Is Required for Efficient Tumor Formation and Progression in a Ras-Mediated Skin Cancer Model
- (2012) H. Y. Chow et al. CANCER RESEARCH
- Genomic Sequencing of Key Genes in Mouse Pancreatic Cancer Cells
- (2012) Y. Wang et al. CURRENT MOLECULAR MEDICINE
- MUC13 Mucin Augments Pancreatic Tumorigenesis
- (2011) S. C. Chauhan et al. MOLECULAR CANCER THERAPEUTICS
- Pancreatic cancer: Overview of descriptive epidemiology
- (2011) Cristina Bosetti et al. MOLECULAR CARCINOGENESIS
- Molecular biology of pancreatic cancer
- (2011) Miroslav Zavoral WORLD JOURNAL OF GASTROENTEROLOGY
- P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways
- (2010) Nhi Huynh et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Development of an Orthotopic Model of Invasive Pancreatic Cancer in an Immunocompetent Murine Host
- (2010) W. W. Tseng et al. CLINICAL CANCER RESEARCH
- Phenotype and Genotype of Pancreatic Cancer Cell Lines
- (2010) Emily L. Deer et al. PANCREAS
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation